FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDF0201, 703 aa 1>>>pF1KSDF0201 703 - 703 aa - 703 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.8706+/-0.00135; mu= -2.8796+/- 0.082 mean_var=691.8839+/-145.956, 0's: 0 Z-trim(115.6): 207 B-trim: 414 in 1/51 Lambda= 0.048759 statistics sampled from 16008 (16209) to 16008 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.74), E-opt: 0.2 (0.498), width: 16 Scan time: 5.020 The best scores are: opt bits E(32554) CCDS403.1 COL8A2 gene_id:1296|Hs108|chr1 ( 703) 5227 383.2 7.2e-106 CCDS72756.1 COL8A2 gene_id:1296|Hs108|chr1 ( 638) 4789 352.3 1.3e-96 CCDS2934.1 COL8A1 gene_id:1295|Hs108|chr3 ( 744) 2644 201.5 3.7e-51 CCDS5105.1 COL10A1 gene_id:1300|Hs108|chr6 ( 680) 2503 191.5 3.4e-48 CCDS14543.1 COL4A5 gene_id:1287|Hs108|chrX (1685) 1599 128.5 8e-29 CCDS35366.1 COL4A5 gene_id:1287|Hs108|chrX (1691) 1599 128.5 8.1e-29 CCDS6982.1 COL5A1 gene_id:1289|Hs108|chr9 (1838) 1588 127.8 1.4e-28 CCDS75932.1 COL5A1 gene_id:1289|Hs108|chr9 (1838) 1588 127.8 1.4e-28 CCDS780.2 COL11A1 gene_id:1301|Hs108|chr1 (1690) 1531 123.7 2.2e-27 CCDS53348.1 COL11A1 gene_id:1301|Hs108|chr1 (1767) 1531 123.7 2.3e-27 CCDS778.1 COL11A1 gene_id:1301|Hs108|chr1 (1806) 1531 123.8 2.3e-27 CCDS33350.1 COL5A2 gene_id:1290|Hs108|chr2 (1499) 1525 123.2 2.8e-27 CCDS8759.1 COL2A1 gene_id:1280|Hs108|chr12 (1418) 1519 122.8 3.6e-27 CCDS41778.1 COL2A1 gene_id:1280|Hs108|chr12 (1487) 1519 122.8 3.7e-27 CCDS6376.1 COL22A1 gene_id:169044|Hs108|chr8 (1626) 1503 121.7 8.5e-27 CCDS12222.1 COL5A3 gene_id:50509|Hs108|chr19 (1745) 1476 119.9 3.3e-26 CCDS9511.1 COL4A1 gene_id:1282|Hs108|chr13 (1669) 1472 119.6 3.9e-26 CCDS41907.1 COL4A2 gene_id:1284|Hs108|chr13 (1712) 1455 118.4 9.1e-26 CCDS47447.1 COL9A1 gene_id:1297|Hs108|chr6 ( 678) 1436 116.5 1.3e-25 CCDS450.1 COL9A2 gene_id:1298|Hs108|chr1 ( 689) 1434 116.3 1.5e-25 CCDS4971.1 COL9A1 gene_id:1297|Hs108|chr6 ( 921) 1436 116.7 1.6e-25 CCDS42829.1 COL4A3 gene_id:1285|Hs108|chr2 (1670) 1426 116.3 3.7e-25 CCDS6802.1 COL27A1 gene_id:85301|Hs108|chr9 (1860) 1410 115.3 8.6e-25 CCDS76010.1 COL4A6 gene_id:1288|Hs108|chrX (1707) 1393 114.0 1.9e-24 CCDS41297.1 COL16A1 gene_id:1307|Hs108|chr1 (1604) 1364 111.9 7.4e-24 CCDS4970.1 COL19A1 gene_id:1310|Hs108|chr6 (1142) 1352 110.9 1.1e-23 CCDS41353.1 COL24A1 gene_id:255631|Hs108|chr1 (1714) 1344 110.6 2e-23 CCDS2773.1 COL7A1 gene_id:1294|Hs108|chr3 (2944) 1349 111.2 2.2e-23 CCDS42828.1 COL4A4 gene_id:1286|Hs108|chr2 (1690) 1342 110.4 2.2e-23 CCDS76649.1 COL4A1 gene_id:1282|Hs108|chr13 ( 519) 1327 108.6 2.3e-23 CCDS44424.2 COL13A1 gene_id:1305|Hs108|chr10 ( 695) 1330 109.0 2.4e-23 CCDS44425.2 COL13A1 gene_id:1305|Hs108|chr10 ( 686) 1307 107.4 7.3e-23 CCDS13505.1 COL9A3 gene_id:1299|Hs108|chr20 ( 684) 1283 105.7 2.3e-22 CCDS44419.1 COL13A1 gene_id:1305|Hs108|chr10 ( 717) 1269 104.8 4.8e-22 CCDS76008.1 COL4A6 gene_id:1288|Hs108|chrX (1633) 1261 104.7 1.1e-21 CCDS76009.1 COL4A6 gene_id:1288|Hs108|chrX (1666) 1261 104.7 1.1e-21 CCDS14542.1 COL4A6 gene_id:1288|Hs108|chrX (1690) 1261 104.7 1.2e-21 CCDS14541.1 COL4A6 gene_id:1288|Hs108|chrX (1691) 1261 104.7 1.2e-21 CCDS58922.1 COL25A1 gene_id:84570|Hs108|chr4 ( 645) 1217 101.0 5.7e-21 CCDS44427.2 COL13A1 gene_id:1305|Hs108|chr10 ( 645) 1209 100.5 8.4e-21 CCDS44428.2 COL13A1 gene_id:1305|Hs108|chr10 ( 610) 1175 98.1 4.3e-20 CCDS44423.2 COL13A1 gene_id:1305|Hs108|chr10 ( 668) 1169 97.7 6e-20 CCDS55025.1 COL21A1 gene_id:81578|Hs108|chr6 ( 957) 1065 90.6 1.2e-17 CCDS83099.1 COL21A1 gene_id:81578|Hs108|chr6 ( 954) 1053 89.7 2.1e-17 CCDS34682.1 COL1A2 gene_id:1278|Hs108|chr7 (1366) 1024 87.9 1.1e-16 CCDS42971.1 COL18A1 gene_id:80781|Hs108|chr21 (1339) 1004 86.5 2.8e-16 CCDS42972.1 COL18A1 gene_id:80781|Hs108|chr21 (1519) 1004 86.6 3e-16 CCDS77643.1 COL18A1 gene_id:80781|Hs108|chr21 (1754) 1004 86.7 3.3e-16 CCDS43553.1 COL28A1 gene_id:340267|Hs108|chr7 (1125) 997 85.9 3.6e-16 CCDS43452.1 COL11A2 gene_id:1302|Hs108|chr6 (1650) 959 83.5 2.8e-15 >>CCDS403.1 COL8A2 gene_id:1296|Hs108|chr1 (703 aa) initn: 5227 init1: 5227 opt: 5227 Z-score: 2014.1 bits: 383.2 E(32554): 7.2e-106 Smith-Waterman score: 5227; 100.0% identity (100.0% similar) in 703 aa overlap (1-703:1-703) 10 20 30 40 50 60 pF1KSD MLGTLTPLSSLLLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 MLGTLTPLSSLLLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 GQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 RMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 PGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 LDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD PGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 PGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD GLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 GLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 GPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 GLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD IAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 IAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD GHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS40 GHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQAS 610 620 630 640 650 660 670 680 690 700 pF1KSD GGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCPT ::::::::::::::::::::::::::::::::::::::::::: CCDS40 GGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCPT 670 680 690 700 >>CCDS72756.1 COL8A2 gene_id:1296|Hs108|chr1 (638 aa) initn: 4789 init1: 4789 opt: 4789 Z-score: 1848.0 bits: 352.3 E(32554): 1.3e-96 Smith-Waterman score: 4789; 100.0% identity (100.0% similar) in 638 aa overlap (66-703:1-638) 40 50 60 70 80 90 pF1KSD AGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPG :::::::::::::::::::::::::::::: CCDS72 MPLPLLPMDLKGEPGPPGKPGPRGPPGPPG 10 20 30 100 110 120 130 140 150 pF1KSD FPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 FPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLR 40 50 60 70 80 90 160 170 180 190 200 210 pF1KSD GPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 GPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGL 100 110 120 130 140 150 220 230 240 250 260 270 pF1KSD PGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 PGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPP 160 170 180 190 200 210 280 290 300 310 320 330 pF1KSD GVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 GVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGL 220 230 240 250 260 270 340 350 360 370 380 390 pF1KSD LGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 LGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGD 280 290 300 310 320 330 400 410 420 430 440 450 pF1KSD QGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 QGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQ 340 350 360 370 380 390 460 470 480 490 500 510 pF1KSD PGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 PGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSP 400 410 420 430 440 450 520 530 540 550 560 570 pF1KSD GITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 GITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATP 460 470 480 490 500 510 580 590 600 610 620 630 pF1KSD AFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 AFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWV 520 530 540 550 560 570 640 650 660 670 680 690 pF1KSD ALYKNNVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 ALYKNNVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSF 580 590 600 610 620 630 700 pF1KSD SGFLLCPT :::::::: CCDS72 SGFLLCPT >>CCDS2934.1 COL8A1 gene_id:1295|Hs108|chr3 (744 aa) initn: 5240 init1: 2003 opt: 2644 Z-score: 1031.9 bits: 201.5 E(32554): 3.7e-51 Smith-Waterman score: 2644; 57.2% identity (71.1% similar) in 671 aa overlap (42-702:88-743) 20 30 40 50 60 70 pF1KSD LLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGP-VGPPFREGKGQYLEMPLPL .:.. .: .: .: ::. :.:: CCDS29 VPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGK--EIPLA- 60 70 80 90 100 110 80 90 100 110 120 130 pF1KSD LPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGL .:.:: :: :.:::::::::::.::. : ::..:.::: : :: .:: : ::. CCDS29 ---SLRGEQGPRGEPGPRGPPGPPGLPGH---GIPGIKGKPGPQGYPG---VGKPGMPGM 120 130 140 150 160 140 150 160 170 180 190 pF1KSD PGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEP ::: : :.:: .:: : .:. : : ::: : ::: :. ::::. :.:: :: .:. CCDS29 PGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDR 170 180 190 200 210 220 200 210 220 230 240 250 pF1KSD GPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGD ::.: ::: : :: :::.: :.:: ::. : : :::: : :.::::. :.:: : CCDS29 GPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGP 230 240 250 260 270 280 260 270 280 290 300 pF1KSD KGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGE---PGTRGPP :. : :: :::.: :. : .::::. :.: :: :.:: : :.::: :: ::: CCDS29 LGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPP 290 300 310 320 330 340 310 320 330 340 350 360 pF1KSD GLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAG :: : : : ::.:::::::: .:::: :: ::: : : :: :: : : ::.:: : CCDS29 GL--P-GIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMG 350 360 370 380 390 400 370 380 390 400 410 420 pF1KSD LPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKG :: : ::::::.: :: : :: .:. : .:. :::: :: : :: .: ::: :::: CCDS29 PPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKG 410 420 430 440 450 460 430 440 450 460 470 480 pF1KSD EPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPG : : : :: ::: : :: ::. :.::. ::.:: ::::. ::.::::: :.:: ::::: CCDS29 EAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPG 470 480 490 500 510 520 490 500 510 520 530 540 pF1KSD LPGPPGEGRAGEPGTAGPTGPPGVPGSPGITG-P--PGPPGPPGPPGAPGAFDETGIA-G :::::: :.::.:: :::: ::. : : : ::::::::::: :... : : CCDS29 LPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQG 530 540 550 560 570 580 550 560 570 580 590 600 pF1KSD LHLPN-G-GVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYNG .::. : :..:. .. . : . :. ::::: ::.::: : ::::.. :::: CCDS29 EYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNG 590 600 610 620 630 640 610 620 630 640 650 660 pF1KSD HSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQASG ...::: :::::: : :::::::::: :: ::::::.::: :. :::::::::.:::::: CCDS29 RQNYNPQTGIFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASG 650 660 670 680 690 700 670 680 690 700 pF1KSD GAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCPT .::: :::.:.:..::::.:: :::. .:.::::::.:: : CCDS29 SAVLLLRPGDRVFLQMPSEQAAGLYAGQYVHSSFSGYLLYPM 710 720 730 740 >>CCDS5105.1 COL10A1 gene_id:1300|Hs108|chr6 (680 aa) initn: 3592 init1: 1912 opt: 2503 Z-score: 978.7 bits: 191.5 E(32554): 3.4e-48 Smith-Waterman score: 2503; 55.5% identity (69.9% similar) in 632 aa overlap (76-702:59-679) 50 60 70 80 90 100 pF1KSD PMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKP .: ::::: :::: ::: : :::::.:.: CCDS51 TGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSP 30 40 50 60 70 80 110 120 130 140 150 160 pF1KSD GLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPG ::.:.:: :::: : .:: : :::::: : : : .:. : : : ::::::::.:: CCDS51 GLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPG 90 100 110 120 130 140 170 180 190 200 210 220 pF1KSD PSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAP :.::..::::: :: : :: .: :: .: :: :: : ::. : : :: :: : : CCDS51 PAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQ 150 160 170 180 190 200 230 240 250 260 270 280 pF1KSD GPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGA :: : :: :.:: : .:.:: :: ::. : :: :: : :: :: : : .:.: ::: CCDS51 GPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGA 210 220 230 240 250 260 290 300 310 320 330 340 pF1KSD AGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGED :: :: : :.:: ::. : : :: :.: ::::: ::.:::::.:: : .:: : CCDS51 AGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPA 270 280 290 300 310 320 350 360 370 380 390 400 pF1KSD GEPGEQGPQGLGGPPGL--P-GSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLA : ::. : :: :::: : : :.:: .: ::::::.::.:: : :: .:..: : CCDS51 GLPGK--P-GLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSD 330 340 350 360 370 380 410 420 430 440 450 460 pF1KSD GKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPS :::: ::. :: : .: :: ::::.:: : :: :: .: : :: : :. : :: CCDS51 GKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAP 390 400 410 420 430 440 470 480 490 500 510 520 pF1KSD GIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPG :::: .:: :: : :.:: ::.:: ::::: . . : ::::::: :: : .: :: CCDS51 GIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPG 450 460 470 480 490 500 530 540 550 560 570 580 pF1KSD PPGPPGPPGAPGAFDETGIAGLHLPNGGVE-GAVLGKGGKPQFGLGE-LSAHATPAFTAV :::::::: :: .. .:.: .. : . .: : . .. ... . :::.. CCDS51 LPGPPGPPGPPGQ----AV----MPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSAFTVI 510 520 530 540 550 590 600 610 620 630 640 pF1KSD LTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKN :.. .:: : :. ::. ::: .. :.: :::::: . :.:::.::::::::.:::.:::: CCDS51 LSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFSYHVHVKGTHVWVGLYKN 560 570 580 590 600 610 650 660 670 680 690 700 pF1KSD NVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLL ..:. :::::: :::::::::.:...: :::::.:.:. ..:::::.::.::::::::. CCDS51 GTPVMYTYDEYTKGYLDQASGSAIIDLTENDQVWLQLPNAESNGLYSSEYVHSSFSGFLV 620 630 640 650 660 670 pF1KSD CPT : CCDS51 APM 680 >>CCDS14543.1 COL4A5 gene_id:1287|Hs108|chrX (1685 aa) initn: 1235 init1: 764 opt: 1599 Z-score: 630.9 bits: 128.5 E(32554): 8e-29 Smith-Waterman score: 1786; 48.7% identity (58.8% similar) in 612 aa overlap (31-591:647-1243) 10 20 30 40 50 60 pF1KSD MLGTLTPLSSLLLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGK : : : :: . : : : :.: CCDS14 IGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGD 620 630 640 650 660 670 70 80 90 100 110 pF1KSD -------GQYLEMPLPLLPMDLKGEPGPPGK--PGPRGPPGPPGFPGKPGM-GKPGLHGQ : . :: .: . ::::: :: ::: :: : ::.:: :: : :: : CCDS14 VGLPGDPGLPGQPGLPGIPGS-KGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 680 690 700 710 720 730 120 130 140 150 160 pF1KSD PGPAGPPGFSRMGKAGPPG--LPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPG------ :: ::::: : : :: ::: :::: ::..: : .::.:. ::::::: CCDS14 EGPPGPPGFP--GPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDG 740 750 760 770 780 790 170 180 190 200 210 pF1KSD LPGPSGITIP-GKPGAQGVPGPPGF--QGEPGPQGEPGP---PGDRGLKGDNG-VGQPGL ::::.: . : :.:: .: :: ::. :: ::: : ::: :: .:. :..: : ::: CCDS14 LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGL 800 810 820 830 840 850 220 230 240 250 260 pF1KSD --PGAPGQGGAPGPPGLPGPAGL-GKPGLDGLPGA---PGDKGESG---PPGVPGPRGEP :: ::. :.:: :: ::: : :.::: : :: :: ::: : ::: ::: : : CCDS14 DVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIP 860 870 880 890 900 910 270 280 290 300 310 320 pF1KSD GAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPG-----LIGPTGY-GMPGL : : : : :: . : ::::: : .:.::::: :::: :.: : : ::: CCDS14 GRSGVPGLKGDDG--LQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL 920 930 940 950 960 970 330 340 350 360 370 380 pF1KSD PGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGE :: : :: : :: :: :.:: .:.:: :: : : :::::. :: :::: :: CCDS14 PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQ---PGLIGPPGLKGT 980 990 1000 1010 1020 390 400 410 420 430 pF1KSD AGPGGPPGVPGIRGDQGPSGLAGKPGVPG------ERGLPGAH--GPPGPTGPKGEPGFT : : :: :..: ::::. :.:: :: ..: :: : :: :::::::. CCDS14 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP 1030 1040 1050 1060 1070 1080 440 450 460 470 480 490 pF1KSD GRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPP : ::.::. :..:. : :::: :: .: :.::. : :: ::.:. : :.::::: : CCDS14 GYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEP 1090 1100 1110 1120 1130 1140 500 510 520 530 540 pF1KSD GE-GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPG--APGAFDETGIAGLHLPNG : : .:.:: :: : : ::. :: :: : : :: :: :: :..: . .: CCDS14 GPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSG-QKGDG 1150 1160 1170 1180 1190 1200 550 560 570 580 590 600 pF1KSD GVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPAT :. : . :. : : :: . :. :. : : : : : CCDS14 GLPG-IPGNPGLPG-PKGEPGFHGFPG---VQGPPGPP-GSPGPALEGPKGNPGPQGPPG 1210 1220 1230 1240 1250 1260 610 620 630 640 650 660 pF1KSD GIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQASGGAVLQLRP CCDS14 RPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKG 1270 1280 1290 1300 1310 1320 >>CCDS35366.1 COL4A5 gene_id:1287|Hs108|chrX (1691 aa) initn: 1235 init1: 764 opt: 1599 Z-score: 630.9 bits: 128.5 E(32554): 8.1e-29 Smith-Waterman score: 1786; 48.7% identity (58.8% similar) in 612 aa overlap (31-591:647-1243) 10 20 30 40 50 60 pF1KSD MLGTLTPLSSLLLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGK : : : :: . : : : :.: CCDS35 IGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGD 620 630 640 650 660 670 70 80 90 100 110 pF1KSD -------GQYLEMPLPLLPMDLKGEPGPPGK--PGPRGPPGPPGFPGKPGM-GKPGLHGQ : . :: .: . ::::: :: ::: :: : ::.:: :: : :: : CCDS35 VGLPGDPGLPGQPGLPGIPGS-KGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 680 690 700 710 720 730 120 130 140 150 160 pF1KSD PGPAGPPGFSRMGKAGPPG--LPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPG------ :: ::::: : : :: ::: :::: ::..: : .::.:. ::::::: CCDS35 EGPPGPPGFP--GPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDG 740 750 760 770 780 790 170 180 190 200 210 pF1KSD LPGPSGITIP-GKPGAQGVPGPPGF--QGEPGPQGEPGP---PGDRGLKGDNG-VGQPGL ::::.: . : :.:: .: :: ::. :: ::: : ::: :: .:. :..: : ::: CCDS35 LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGL 800 810 820 830 840 850 220 230 240 250 260 pF1KSD --PGAPGQGGAPGPPGLPGPAGL-GKPGLDGLPGA---PGDKGESG---PPGVPGPRGEP :: ::. :.:: :: ::: : :.::: : :: :: ::: : ::: ::: : : CCDS35 DVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIP 860 870 880 890 900 910 270 280 290 300 310 320 pF1KSD GAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPG-----LIGPTGY-GMPGL : : : : :: . : ::::: : .:.::::: :::: :.: : : ::: CCDS35 GRSGVPGLKGDDG--LQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL 920 930 940 950 960 970 330 340 350 360 370 380 pF1KSD PGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGE :: : :: : :: :: :.:: .:.:: :: : : :::::. :: :::: :: CCDS35 PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQ---PGLIGPPGLKGT 980 990 1000 1010 1020 390 400 410 420 430 pF1KSD AGPGGPPGVPGIRGDQGPSGLAGKPGVPG------ERGLPGAH--GPPGPTGPKGEPGFT : : :: :..: ::::. :.:: :: ..: :: : :: :::::::. CCDS35 IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP 1030 1040 1050 1060 1070 1080 440 450 460 470 480 490 pF1KSD GRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPP : ::.::. :..:. : :::: :: .: :.::. : :: ::.:. : :.::::: : CCDS35 GYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEP 1090 1100 1110 1120 1130 1140 500 510 520 530 540 pF1KSD GE-GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPG--APGAFDETGIAGLHLPNG : : .:.:: :: : : ::. :: :: : : :: :: :: :..: . .: CCDS35 GPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSG-QKGDG 1150 1160 1170 1180 1190 1200 550 560 570 580 590 600 pF1KSD GVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPAT :. : . :. : : :: . :. :. : : : : : CCDS35 GLPG-IPGNPGLPG-PKGEPGFHGFPG---VQGPPGPP-GSPGPALEGPKGNPGPQGPPG 1210 1220 1230 1240 1250 1260 610 620 630 640 650 660 pF1KSD GIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQASGGAVLQLRP CCDS35 RPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPG 1270 1280 1290 1300 1310 1320 >>CCDS6982.1 COL5A1 gene_id:1289|Hs108|chr9 (1838 aa) initn: 619 init1: 619 opt: 1588 Z-score: 626.3 bits: 127.8 E(32554): 1.4e-28 Smith-Waterman score: 1662; 46.8% identity (56.9% similar) in 601 aa overlap (23-562:985-1563) 10 20 30 40 pF1KSD MLGTLTPLSSLLLLLLVLVLGCGPRASSGG-GAGGAAG-YAPVKYIQPM-QK : ....: : :..: .:. :: .. CCDS69 GPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGER 960 970 980 990 1000 1010 50 60 70 80 90 100 pF1KSD GPVGPPFREGKGQYLEMPLPLLP--MDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKP-- : ::: : :. :: : ::.::: : :: :::: :::: :. : CCDS69 GHPGPP-----GPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVG 1020 1030 1040 1050 1060 110 120 130 140 150 pF1KSD --GLHGQPGPAGPPGFSR-------MGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRG ::.:. :: :::: . : ::: :.::. :: : :: :: : :..: .: CCDS69 ALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQG 1070 1080 1090 1100 1110 1120 160 170 180 190 200 pF1KSD PPG------PPGLPGPSG-ITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG : : : :::::.: . ::. : .: : :: .: : .:: :::: : .: CCDS69 PAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGP-- 1130 1140 1150 1160 1170 1180 210 220 230 240 250 pF1KSD VGQPGLPGA---PG----QG-----GAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESG-- .:::: :: :: :: : :: :.::: : ::.:::: ::.:::.: CCDS69 IGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPP--GPVGLQGLPGPPGEKGETGDV 1190 1200 1210 1220 1230 1240 260 270 280 290 300 pF1KSD ----PPGVPGPRGE---PGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPG ::: ::::: ::: ::.:::: :.: :::.: : : .: : :: :::: CCDS69 GQMGPPGPPGPRGPSGAPGADGPQGPPG--GIGNPGAVGEKGEPGEAGEPGLPGEGGPPG 1250 1260 1270 1280 1290 1300 310 320 330 340 350 pF1KSD ---------LIGPTGY-GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGG ::.: : :: :: :: :: : :: .: ::. : ::: :: : : CCDS69 PKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVG---FPGDPGPPGEPGPAGQDG 1310 1320 1330 1340 1350 1360 360 370 380 390 400 410 pF1KSD PPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHG ::: :. : ::. : ::: :: ::.:::: :: ::.: :. : : .: : .: CCDS69 PPGDKGDDGEPGQTGSPGPTGEPGPSGPPGK---RGPPGPAGPEGRQGEKGAKGEAGLEG 1370 1380 1390 1400 1410 420 430 440 450 460 470 pF1KSD PPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSG------IPGLQGPAG ::: ::: : : :.:: :. : : :. ::::.:: :: : .:::.: .: CCDS69 PPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSG 1420 1430 1440 1450 1460 1470 480 490 500 510 520 530 pF1KSD PIGPQGLPGLKGEPGLPGPPGE-GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPG : : .: ::: :: ::::: :. :. : :: : : : ::::: :: ::::::: CCDS69 PKGEKGHPGL---IGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPG 1480 1490 1500 1510 1520 1530 540 550 560 570 580 590 pF1KSD APGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMP :: : : :.: .: . :. : : CCDS69 LPGPPGPKGAKGSSGPTGP-KGEA-GHPGPPGPPGPPGEVIQPLPIQASRTRRNIDASQL 1540 1550 1560 1570 1580 1590 600 610 620 630 640 650 pF1KSD VKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEY CCDS69 LDDGNGENYVDYADGMEEIFGSLNSLKLEIEQMKRPLGTQQNPARTCKDLQLCHPDFPDG 1600 1610 1620 1630 1640 1650 >-- initn: 603 init1: 603 opt: 1117 Z-score: 447.3 bits: 94.6 E(32554): 1.4e-18 Smith-Waterman score: 1484; 46.8% identity (54.5% similar) in 547 aa overlap (48-539:451-984) 20 30 40 50 60 70 pF1KSD LVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPL-PLLPMDLK .:: : : :. .: : : : : CCDS69 YDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLP 430 440 450 460 470 480 80 90 100 110 pF1KSD GEPG---PPGK---PGPRGPPGPPGFPGKPGM-GKPGLH-------GQPGPAGPPGF--- : :: : :. :: ::::: ::.:: :. : :: : : :: : CCDS69 GPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVS 490 500 510 520 530 540 120 130 140 150 160 pF1KSD ------------SRM---GKAGPPGL---PGKVGPPGQPGLRGEPGIRGDQGLRGPPGPP .:. : ::: :: :: :::::. ::.:::: : :: :: ::: CCDS69 AQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPP 550 560 570 580 590 600 170 180 190 200 210 220 pF1KSD GLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGV-GQPGLPGAPG : :.: ::: .: : : .: : :. :: ::::. : :. :. : : :: CCDS69 G---PAG-----KPGRRGRAGSDGARGMP---GQTGPKGDRGFDGLAGLPGEKGHRGDPG 610 620 630 640 230 240 250 260 270 pF1KSD QGGAPGPPGLPGPAGL-GKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDG .: ::::: : : :. : :::: :: .: :: : ::: : ::..: : :: : CCDS69 PSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKG 650 660 670 680 690 700 280 290 300 310 320 330 pF1KSD -VGVPGAAGLPGPQGPSGAKGEPGTRG---PPGLIGPTGYGMPGLPGPKGDRGPAGVPGL :: : : :: :: ::.: :: .: ::: :: : ::::: : :: : :: CCDS69 NVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGK--PGLPGMPGADGPPGHPGK 710 720 730 740 750 760 340 350 360 370 380 390 pF1KSD LGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAG-PG--GPPGVPGI : :: : .: :: ::: : :: :. :. :. : .: : ::: : :: : :. : CCDS69 EGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGD 770 780 790 800 810 820 400 410 420 430 440 450 pF1KSD RGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGL ::. :: : :. : : .: : .: ::: :: :: : : :: :: : : ::..:. CCDS69 RGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGF 830 840 850 860 870 880 460 470 480 490 500 pF1KSD PGQPGL------RGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG----EGRAGEPGT :: :: :: : :: .: :: ::.: : .: : ::: : .: :: :: CCDS69 PGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGE 890 900 910 920 930 940 510 520 530 540 550 560 pF1KSD AGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKP ::.:: : : :: ::::::: : :: :: :: CCDS69 RGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGE 950 960 970 980 990 1000 570 580 590 600 610 620 pF1KSD QFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYF CCDS69 TGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGP 1010 1020 1030 1040 1050 1060 >>CCDS75932.1 COL5A1 gene_id:1289|Hs108|chr9 (1838 aa) initn: 619 init1: 619 opt: 1588 Z-score: 626.3 bits: 127.8 E(32554): 1.4e-28 Smith-Waterman score: 1662; 46.8% identity (56.9% similar) in 601 aa overlap (23-562:985-1563) 10 20 30 40 pF1KSD MLGTLTPLSSLLLLLLVLVLGCGPRASSGG-GAGGAAG-YAPVKYIQPM-QK : ....: : :..: .:. :: .. CCDS75 GPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGER 960 970 980 990 1000 1010 50 60 70 80 90 100 pF1KSD GPVGPPFREGKGQYLEMPLPLLP--MDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKP-- : ::: : :. :: : ::.::: : :: :::: :::: :. : CCDS75 GHPGPP-----GPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVG 1020 1030 1040 1050 1060 110 120 130 140 150 pF1KSD --GLHGQPGPAGPPGFSR-------MGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRG ::.:. :: :::: . : ::: :.::. :: : :: :: : :..: .: CCDS75 ALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQG 1070 1080 1090 1100 1110 1120 160 170 180 190 200 pF1KSD PPG------PPGLPGPSG-ITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNG : : : :::::.: . ::. : .: : :: .: : .:: :::: : .: CCDS75 PAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGP-- 1130 1140 1150 1160 1170 1180 210 220 230 240 250 pF1KSD VGQPGLPGA---PG----QG-----GAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESG-- .:::: :: :: :: : :: :.::: : ::.:::: ::.:::.: CCDS75 IGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPP--GPVGLQGLPGPPGEKGETGDV 1190 1200 1210 1220 1230 1240 260 270 280 290 300 pF1KSD ----PPGVPGPRGE---PGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPG ::: ::::: ::: ::.:::: :.: :::.: : : .: : :: :::: CCDS75 GQMGPPGPPGPRGPSGAPGADGPQGPPG--GIGNPGAVGEKGEPGEAGEPGLPGEGGPPG 1250 1260 1270 1280 1290 1300 310 320 330 340 350 pF1KSD ---------LIGPTGY-GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGG ::.: : :: :: :: :: : :: .: ::. : ::: :: : : CCDS75 PKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVG---FPGDPGPPGEPGPAGQDG 1310 1320 1330 1340 1350 1360 360 370 380 390 400 410 pF1KSD PPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHG ::: :. : ::. : ::: :: ::.:::: :: ::.: :. : : .: : .: CCDS75 PPGDKGDDGEPGQTGSPGPTGEPGPSGPPGK---RGPPGPAGPEGRQGEKGAKGEAGLEG 1370 1380 1390 1400 1410 420 430 440 450 460 470 pF1KSD PPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSG------IPGLQGPAG ::: ::: : : :.:: :. : : :. ::::.:: :: : .:::.: .: CCDS75 PPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSG 1420 1430 1440 1450 1460 1470 480 490 500 510 520 530 pF1KSD PIGPQGLPGLKGEPGLPGPPGE-GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPG : : .: ::: :: ::::: :. :. : :: : : : ::::: :: ::::::: CCDS75 PKGEKGHPGL---IGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPG 1480 1490 1500 1510 1520 1530 540 550 560 570 580 590 pF1KSD APGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMP :: : : :.: .: . :. : : CCDS75 LPGPPGPKGAKGSSGPTGP-KGEA-GHPGPPGPPGPPGEVIQPLPIQASRTRRNIDASQL 1540 1550 1560 1570 1580 1590 600 610 620 630 640 650 pF1KSD VKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEY CCDS75 LDDGNGENYVDYADGMEEIFGSLNSLKLEIEQMKRPLGTQQNPARTCKDLQLCHPDFPDG 1600 1610 1620 1630 1640 1650 >-- initn: 603 init1: 603 opt: 1117 Z-score: 447.3 bits: 94.6 E(32554): 1.4e-18 Smith-Waterman score: 1484; 46.8% identity (54.5% similar) in 547 aa overlap (48-539:451-984) 20 30 40 50 60 70 pF1KSD LVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPL-PLLPMDLK .:: : : :. .: : : : : CCDS75 YDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLP 430 440 450 460 470 480 80 90 100 110 pF1KSD GEPG---PPGK---PGPRGPPGPPGFPGKPGM-GKPGLH-------GQPGPAGPPGF--- : :: : :. :: ::::: ::.:: :. : :: : : :: : CCDS75 GPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVS 490 500 510 520 530 540 120 130 140 150 160 pF1KSD ------------SRM---GKAGPPGL---PGKVGPPGQPGLRGEPGIRGDQGLRGPPGPP .:. : ::: :: :: :::::. ::.:::: : :: :: ::: CCDS75 AQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPP 550 560 570 580 590 600 170 180 190 200 210 220 pF1KSD GLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGV-GQPGLPGAPG : :.: ::: .: : : .: : :. :: ::::. : :. :. : : :: CCDS75 G---PAG-----KPGRRGRAGSDGARGMP---GQTGPKGDRGFDGLAGLPGEKGHRGDPG 610 620 630 640 230 240 250 260 270 pF1KSD QGGAPGPPGLPGPAGL-GKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDG .: ::::: : : :. : :::: :: .: :: : ::: : ::..: : :: : CCDS75 PSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKG 650 660 670 680 690 700 280 290 300 310 320 330 pF1KSD -VGVPGAAGLPGPQGPSGAKGEPGTRG---PPGLIGPTGYGMPGLPGPKGDRGPAGVPGL :: : : :: :: ::.: :: .: ::: :: : ::::: : :: : :: CCDS75 NVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGK--PGLPGMPGADGPPGHPGK 710 720 730 740 750 760 340 350 360 370 380 390 pF1KSD LGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAG-PG--GPPGVPGI : :: : .: :: ::: : :: :. :. :. : .: : ::: : :: : :. : CCDS75 EGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGD 770 780 790 800 810 820 400 410 420 430 440 450 pF1KSD RGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGL ::. :: : :. : : .: : .: ::: :: :: : : :: :: : : ::..:. CCDS75 RGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGF 830 840 850 860 870 880 460 470 480 490 500 pF1KSD PGQPGL------RGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG----EGRAGEPGT :: :: :: : :: .: :: ::.: : .: : ::: : .: :: :: CCDS75 PGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGE 890 900 910 920 930 940 510 520 530 540 550 560 pF1KSD AGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKP ::.:: : : :: ::::::: : :: :: :: CCDS75 RGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGE 950 960 970 980 990 1000 570 580 590 600 610 620 pF1KSD QFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYF CCDS75 TGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGP 1010 1020 1030 1040 1050 1060 >>CCDS780.2 COL11A1 gene_id:1301|Hs108|chr1 (1690 aa) initn: 1167 init1: 593 opt: 1531 Z-score: 605.0 bits: 123.7 E(32554): 2.2e-27 Smith-Waterman score: 1620; 43.9% identity (56.0% similar) in 647 aa overlap (23-610:839-1465) 10 20 30 40 pF1KSD MLGTLTPLSSLLLLLLVLVLGCGPRASSGG-GAGGAAG-YAPVKYIQPM--- : ....: : ::..: .:. :. CCDS78 GPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGER 810 820 830 840 850 860 50 60 70 80 90 100 pF1KSD -QKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM---- . :: ::: ..: .: ::.::: : : :: : ::::. :. CCDS78 GHPGPPGPPGEQG------LPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQ 870 880 890 900 910 920 110 120 130 140 150 pF1KSD GKPGLHGQPGPAGPPG-------FSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLR : :::.: :: :::: . : ::: ::::. :: : :: :: : :..: . CCDS78 GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQ 930 940 950 960 970 980 160 170 180 190 200 pF1KSD GPPG------PPGLPGPSGIT-IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDN :: : : :::::.: . ::. : .: : :: .: : .:: :::: ::.: CCDS78 GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPV 990 1000 1010 1020 1030 1040 210 220 230 240 250 pF1KSD GV-------GQPG---LPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESG--- :. :.:: : :: : : :.::: : ::.:::: ::.:::.: CCDS78 GAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG--PIGLQGLPGPPGEKGENGDVG 1050 1060 1070 1080 1090 1100 260 270 280 290 300 pF1KSD ---PPGVPGPRGE--P-GAVGPKGPPG----VDGVGV---PGAAGLPGPQGPSGAKGEPG ::: ::::: : :: ::.:::: : ::: :: :: ::: : .:. : : CCDS78 PMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKG 1110 1120 1130 1140 1150 1160 310 320 330 340 350 360 pF1KSD TRGPPGLIGPTGY-GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPG :: : :: : : :: :: :: :: : :: .: :.:: :::: : .:.:: : CCDS78 ERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKG 1170 1180 1190 1200 1210 1220 370 380 390 400 410 420 pF1KSD LPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPG :. ::. :::::.::::: :::: :: : .: :. : : .: ::.:::: CCDS78 EDGD---PGQPGPPGPSGEAGPPGPPGK---RGPPGAAGAEGRQGEKGAKGEAGAEGPPG 1230 1240 1250 1260 1270 430 440 450 460 470 pF1KSD PTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQ------PGLRGPSGIPGLQGPAGPIG ::: : : .:.:: :. : : :. :::: :: :: :.:::.: : : CCDS78 KTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKG 1280 1290 1300 1310 1320 1330 480 490 500 510 520 530 pF1KSD PQGLPGLKGEPGLPGPPGE-GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPG .: ::: :: ::::: :. :. : : : ::. :. :: :: :: ::::::: :: CCDS78 EKGHPGL---IGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPG 1340 1350 1360 1370 1380 1390 540 550 560 570 580 590 pF1KSD AFDETGIAGLHLPNGGV-EGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVK : : : : .... : :.: ::. . : ... : . :: . CCDS78 PQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP-GEV-IQPLPILSSKKTRRH-TEGMQAD 1400 1410 1420 1430 1440 600 610 620 630 640 650 pF1KSD FDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKK : .. . .:.. : CCDS78 ADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWI 1450 1460 1470 1480 1490 1500 >-- initn: 585 init1: 585 opt: 1029 Z-score: 414.2 bits: 88.4 E(32554): 9.5e-17 Smith-Waterman score: 1500; 45.2% identity (54.8% similar) in 571 aa overlap (28-539:301-838) 10 20 30 40 50 pF1KSD MLGTLTPLSSLLLLLLVLVLGCGPRASSGGGAGGAAGYA--PVKYIQP--MQKGPVG .: :: : : :. ..: . .:: : CCDS78 YEYGEAEYKEAESVTEGPTVTEETIAQTEINGHGAYGEKGQKGEPA-VVEPGMLVEGPPG 280 290 300 310 320 60 70 80 90 100 pF1KSD PPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM-GKPGL----- : : . : :.: :::: :: ::::: ::.:: :. : :: CCDS78 PAGPAGI---------MGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLP 330 340 350 360 370 380 110 120 130 140 pF1KSD --HGQPGPAGPPGFSRMGKA------------GPPG------LPGKVGPPGQPGLRGE-- .: : :: .. ..: :::: :: :: ::. : .:: CCDS78 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 390 400 410 420 430 440 150 160 170 180 pF1KSD -PGIRGDQGLRGPPGPPGLPG----PS---GITIPGKPGAQG---------VPGPPGFQG :: .: .:..::::: : :: :. : .::.:::.: .:: : .: CCDS78 DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRG 450 460 470 480 490 500 190 200 210 220 230 240 pF1KSD EPGPQGEPGPPGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPGPAGL-GKPGLDGLPG : :::: :::::: :..:..: .: :::: : : :: : :: : : :.:: :: CCDS78 ERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 510 520 530 540 550 560 250 260 270 280 290 pF1KSD APGD---KGESGPPGV---PGPRGEPGAVGPKGPPGVDGV-GVPGAAGLPGPQGPSGAKG :. .:: :::: :::.: :: :: :::: : : :: ::::: .:: : : CCDS78 PKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPG 570 580 590 600 610 620 300 310 320 330 340 350 pF1KSD EPGTRGPPGLIGPTGYGMP-GLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGG . : : : .:: : : : :::.: .: :: :: :..:: :::: :: .: .:: : CCDS78 KEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKG 630 640 650 660 670 680 360 370 380 390 400 410 pF1KSD PPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHG : :. : :. :: ::::.::: : :: ::: ::. :. :.:: : CCDS78 DRGEVGQIGPRGEDGPEGPKGRAGPTGDPG---------PSGQAGE---KGKLGVPGLPG 690 700 710 720 420 430 440 450 460 470 pF1KSD PPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQG :: :::: :: :: :: :.:: :. :.:: :: : : .: : :: : CCDS78 YPGRQGPKGSTGF------PGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTG 730 740 750 760 770 780 480 490 500 510 520 530 pF1KSD LPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDE :: :: : :::: :: :: :: : : :: ::::::: : :: :: : CCDS78 KPGPKGTSGGDGPPGP-----PGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGE 790 800 810 820 830 540 550 560 570 580 590 pF1KSD TGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTL : CCDS78 TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 840 850 860 870 880 890 >>CCDS53348.1 COL11A1 gene_id:1301|Hs108|chr1 (1767 aa) initn: 1167 init1: 593 opt: 1531 Z-score: 604.8 bits: 123.7 E(32554): 2.3e-27 Smith-Waterman score: 1620; 43.9% identity (56.0% similar) in 647 aa overlap (23-610:916-1542) 10 20 30 40 pF1KSD MLGTLTPLSSLLLLLLVLVLGCGPRASSGG-GAGGAAG-YAPVKYIQPM--- : ....: : ::..: .:. :. CCDS53 GPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGER 890 900 910 920 930 940 50 60 70 80 90 100 pF1KSD -QKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM---- . :: ::: ..: .: ::.::: : : :: : ::::. :. CCDS53 GHPGPPGPPGEQG------LPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQ 950 960 970 980 990 110 120 130 140 150 pF1KSD GKPGLHGQPGPAGPPG-------FSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLR : :::.: :: :::: . : ::: ::::. :: : :: :: : :..: . CCDS53 GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQ 1000 1010 1020 1030 1040 1050 160 170 180 190 200 pF1KSD GPPG------PPGLPGPSGIT-IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDN :: : : :::::.: . ::. : .: : :: .: : .:: :::: ::.: CCDS53 GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPV 1060 1070 1080 1090 1100 1110 210 220 230 240 250 pF1KSD GV-------GQPG---LPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESG--- :. :.:: : :: : : :.::: : ::.:::: ::.:::.: CCDS53 GAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG--PIGLQGLPGPPGEKGENGDVG 1120 1130 1140 1150 1160 1170 260 270 280 290 300 pF1KSD ---PPGVPGPRGE--P-GAVGPKGPPG----VDGVGV---PGAAGLPGPQGPSGAKGEPG ::: ::::: : :: ::.:::: : ::: :: :: ::: : .:. : : CCDS53 PMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKG 1180 1190 1200 1210 1220 1230 310 320 330 340 350 360 pF1KSD TRGPPGLIGPTGY-GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPG :: : :: : : :: :: :: :: : :: .: :.:: :::: : .:.:: : CCDS53 ERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKG 1240 1250 1260 1270 1280 1290 370 380 390 400 410 420 pF1KSD LPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPG :. ::. :::::.::::: :::: :: : .: :. : : .: ::.:::: CCDS53 EDGD---PGQPGPPGPSGEAGPPGPPGK---RGPPGAAGAEGRQGEKGAKGEAGAEGPPG 1300 1310 1320 1330 1340 1350 430 440 450 460 470 pF1KSD PTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQ------PGLRGPSGIPGLQGPAGPIG ::: : : .:.:: :. : : :. :::: :: :: :.:::.: : : CCDS53 KTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKG 1360 1370 1380 1390 1400 1410 480 490 500 510 520 530 pF1KSD PQGLPGLKGEPGLPGPPGE-GRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPG .: ::: :: ::::: :. :. : : : ::. :. :: :: :: ::::::: :: CCDS53 EKGHPGL---IGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPG 1420 1430 1440 1450 1460 540 550 560 570 580 590 pF1KSD AFDETGIAGLHLPNGGV-EGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVK : : : : .... : :.: ::. . : ... : . :: . CCDS53 PQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP-GEV-IQPLPILSSKKTRRH-TEGMQAD 1470 1480 1490 1500 1510 1520 600 610 620 630 640 650 pF1KSD FDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKK : .. . .:.. : CCDS53 ADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWI 1530 1540 1550 1560 1570 1580 >-- initn: 585 init1: 585 opt: 1049 Z-score: 421.6 bits: 89.8 E(32554): 3.7e-17 Smith-Waterman score: 1500; 45.2% identity (54.8% similar) in 571 aa overlap (28-539:378-915) 10 20 30 40 50 pF1KSD MLGTLTPLSSLLLLLLVLVLGCGPRASSGGGAGGAAGYA--PVKYIQP--MQKGPVG .: :: : : :. ..: . .:: : CCDS53 KEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPA-VVEPGMLVEGPPG 350 360 370 380 390 400 60 70 80 90 100 pF1KSD PPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGM-GKPGL----- : : . : :.: :::: :: ::::: ::.:: :. : :: CCDS53 PAGPAGI---------MGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLP 410 420 430 440 450 110 120 130 140 pF1KSD --HGQPGPAGPPGFSRMGKA------------GPPG------LPGKVGPPGQPGLRGE-- .: : :: .. ..: :::: :: :: ::. : .:: CCDS53 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 460 470 480 490 500 510 150 160 170 180 pF1KSD -PGIRGDQGLRGPPGPPGLPG----PS---GITIPGKPGAQG---------VPGPPGFQG :: .: .:..::::: : :: :. : .::.:::.: .:: : .: CCDS53 DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRG 520 530 540 550 560 570 190 200 210 220 230 240 pF1KSD EPGPQGEPGPPGDRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPGPAGL-GKPGLDGLPG : :::: :::::: :..:..: .: :::: : : :: : :: : : :.:: :: CCDS53 ERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 580 590 600 610 620 630 250 260 270 280 290 pF1KSD APGD---KGESGPPGV---PGPRGEPGAVGPKGPPGVDGV-GVPGAAGLPGPQGPSGAKG :. .:: :::: :::.: :: :: :::: : : :: ::::: .:: : : CCDS53 PKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPG 640 650 660 670 680 690 300 310 320 330 340 350 pF1KSD EPGTRGPPGLIGPTGYGMP-GLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGG . : : : .:: : : : :::.: .: :: :: :..:: :::: :: .: .:: : CCDS53 KEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKG 700 710 720 730 740 750 360 370 380 390 400 410 pF1KSD PPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHG : :. : :. :: ::::.::: : :: ::: ::. :. :.:: : CCDS53 DRGEVGQIGPRGEDGPEGPKGRAGPTGDPG---------PSGQAGE---KGKLGVPGLPG 760 770 780 790 800 420 430 440 450 460 470 pF1KSD PPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQG :: :::: :: :: :: :.:: :. :.:: :: : : .: : :: : CCDS53 YPGRQGPKGSTGF------PGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTG 810 820 830 840 850 480 490 500 510 520 530 pF1KSD LPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDE :: :: : :::: :: :: :: : : :: ::::::: : :: :: : CCDS53 KPGPKGTSGGDGPPGP-----PGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGE 860 870 880 890 900 910 540 550 560 570 580 590 pF1KSD TGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTL : CCDS53 TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 920 930 940 950 960 970 703 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:56:28 2016 done: Thu Nov 3 08:56:29 2016 Total Scan time: 5.020 Total Display time: 0.270 Function used was FASTA [36.3.4 Apr, 2011]