FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDF0201, 703 aa 1>>>pF1KSDF0201 703 - 703 aa - 703 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 15.4591+/-0.000566; mu= -24.0774+/- 0.035 mean_var=800.7260+/-171.641, 0's: 0 Z-trim(123.3): 518 B-trim: 3375 in 2/57 Lambda= 0.045324 statistics sampled from 42156 (42773) to 42156 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.502), width: 16 Scan time: 14.930 The best scores are: opt bits E(85289) NP_005193 (OMIM: 120252,136800,609140) collagen al ( 703) 5227 357.5 1e-97 XP_005270534 (OMIM: 120252,136800,609140) PREDICTE ( 780) 5227 357.5 1.1e-97 NP_001281276 (OMIM: 120252,136800,609140) collagen ( 638) 4789 328.8 4e-89 NP_065084 (OMIM: 120251) collagen alpha-1(VIII) ch ( 744) 2644 188.6 7.5e-47 NP_001841 (OMIM: 120251) collagen alpha-1(VIII) ch ( 744) 2644 188.6 7.5e-47 XP_011533734 (OMIM: 120110,156500) PREDICTED: coll ( 680) 2503 179.3 4.2e-44 NP_000484 (OMIM: 120110,156500) collagen alpha-1(X ( 680) 2503 179.3 4.2e-44 XP_016865737 (OMIM: 120110,156500) PREDICTED: coll ( 680) 2503 179.3 4.2e-44 XP_011533735 (OMIM: 120110,156500) PREDICTED: coll ( 680) 2503 179.3 4.2e-44 XP_006715396 (OMIM: 120110,156500) PREDICTED: coll ( 680) 2503 179.3 4.2e-44 XP_016865738 (OMIM: 120110,156500) PREDICTED: coll ( 680) 2503 179.3 4.2e-44 XP_011522643 (OMIM: 114000,120150,130000,130060,16 (1398) 1667 125.0 2e-27 XP_005257116 (OMIM: 114000,120150,130000,130060,16 (1158) 1610 121.2 2.3e-26 XP_016884751 (OMIM: 301050,303630) PREDICTED: coll (1289) 1599 120.5 4.1e-26 XP_016884750 (OMIM: 301050,303630) PREDICTED: coll (1330) 1599 120.5 4.2e-26 XP_016884752 (OMIM: 301050,303630) PREDICTED: coll (1136) 1595 120.2 4.5e-26 NP_000486 (OMIM: 301050,303630) collagen alpha-5(I (1685) 1599 120.6 4.9e-26 XP_016884749 (OMIM: 301050,303630) PREDICTED: coll (1690) 1599 120.6 4.9e-26 NP_203699 (OMIM: 301050,303630) collagen alpha-5(I (1691) 1599 120.6 4.9e-26 XP_016884748 (OMIM: 301050,303630) PREDICTED: coll (1693) 1599 120.6 4.9e-26 XP_011529151 (OMIM: 301050,303630) PREDICTED: coll (1696) 1599 120.6 4.9e-26 XP_016869755 (OMIM: 120215,130000) PREDICTED: coll (1715) 1588 119.9 8.2e-26 NP_000084 (OMIM: 120215,130000) collagen alpha-1(V (1838) 1588 119.9 8.6e-26 NP_001265003 (OMIM: 120215,130000) collagen alpha- (1838) 1588 119.9 8.6e-26 XP_011517446 (OMIM: 608461,615155) PREDICTED: coll (1352) 1553 117.5 3.4e-25 XP_011517445 (OMIM: 608461,615155) PREDICTED: coll (1353) 1553 117.5 3.4e-25 XP_016855825 (OMIM: 120280,154780,228520,603932,60 (1515) 1545 117.0 5.3e-25 XP_011517444 (OMIM: 608461,615155) PREDICTED: coll (1401) 1538 116.6 6.9e-25 XP_016855826 (OMIM: 120280,154780,228520,603932,60 (1323) 1531 116.1 9.1e-25 NP_542197 (OMIM: 120280,154780,228520,603932,60484 (1690) 1531 116.2 1.1e-24 NP_001177638 (OMIM: 120280,154780,228520,603932,60 (1767) 1531 116.2 1.1e-24 NP_001845 (OMIM: 120280,154780,228520,603932,60484 (1806) 1531 116.2 1.1e-24 NP_542196 (OMIM: 120280,154780,228520,603932,60484 (1818) 1531 116.2 1.1e-24 XP_016855824 (OMIM: 120280,154780,228520,603932,60 (1855) 1531 116.2 1.1e-24 XP_016855823 (OMIM: 120280,154780,228520,603932,60 (1857) 1531 116.2 1.1e-24 XP_011508875 (OMIM: 120190,130000) PREDICTED: coll (1453) 1525 115.7 1.3e-24 XP_016870728 (OMIM: 608461,615155) PREDICTED: coll (1214) 1522 115.4 1.3e-24 NP_000384 (OMIM: 120190,130000) collagen alpha-2(V (1499) 1525 115.7 1.3e-24 XP_016874320 (OMIM: 108300,120140,132450,150600,15 (1305) 1519 115.3 1.5e-24 NP_149162 (OMIM: 108300,120140,132450,150600,15121 (1418) 1519 115.3 1.6e-24 XP_016874319 (OMIM: 108300,120140,132450,150600,15 (1465) 1519 115.3 1.7e-24 NP_001835 (OMIM: 108300,120140,132450,150600,15121 (1487) 1519 115.3 1.7e-24 XP_016874318 (OMIM: 108300,120140,132450,150600,15 (1534) 1519 115.4 1.7e-24 XP_016874317 (OMIM: 108300,120140,132450,150600,15 (1535) 1519 115.4 1.7e-24 NP_690848 (OMIM: 610026) collagen alpha-1(XXII) ch (1626) 1503 114.3 3.7e-24 XP_016882338 (OMIM: 120216) PREDICTED: collagen al ( 966) 1476 112.3 8.8e-24 XP_011526344 (OMIM: 120216) PREDICTED: collagen al (1744) 1476 112.6 1.3e-23 NP_056534 (OMIM: 120216) collagen alpha-3(V) chain (1745) 1476 112.6 1.3e-23 XP_011519350 (OMIM: 120130,175780,180000,607595,61 (1605) 1472 112.3 1.5e-23 XP_011515191 (OMIM: 610026) PREDICTED: collagen al (1058) 1465 111.7 1.5e-23 >>NP_005193 (OMIM: 120252,136800,609140) collagen alpha- (703 aa) initn: 5227 init1: 5227 opt: 5227 Z-score: 1875.3 bits: 357.5 E(85289): 1e-97 Smith-Waterman score: 5227; 100.0% identity (100.0% similar) in 703 aa overlap (1-703:1-703) 10 20 30 40 50 60 pF1KSD MLGTLTPLSSLLLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MLGTLTPLSSLLLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD GQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD PGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD LDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD PGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD GLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD GPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD IAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 IAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD GHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQAS 610 620 630 640 650 660 670 680 690 700 pF1KSD GGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCPT ::::::::::::::::::::::::::::::::::::::::::: NP_005 GGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCPT 670 680 690 700 >>XP_005270534 (OMIM: 120252,136800,609140) PREDICTED: c (780 aa) initn: 5227 init1: 5227 opt: 5227 Z-score: 1874.7 bits: 357.5 E(85289): 1.1e-97 Smith-Waterman score: 5227; 100.0% identity (100.0% similar) in 703 aa overlap (1-703:78-780) 10 20 30 pF1KSD MLGTLTPLSSLLLLLLVLVLGCGPRASSGG :::::::::::::::::::::::::::::: XP_005 LLSSRVRPHRPCLCWNLPRPLRPESTSTDAMLGTLTPLSSLLLLLLVLVLGCGPRASSGG 50 60 70 80 90 100 40 50 60 70 80 90 pF1KSD GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGP 110 120 130 140 150 160 100 110 120 130 140 150 pF1KSD PGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRG 170 180 190 200 210 220 160 170 180 190 200 210 pF1KSD DQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGV 230 240 250 260 270 280 220 230 240 250 260 270 pF1KSD GQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVG 290 300 310 320 330 340 280 290 300 310 320 330 pF1KSD PKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPA 350 360 370 380 390 400 340 350 360 370 380 390 pF1KSD GVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVP 410 420 430 440 450 460 400 410 420 430 440 450 pF1KSD GIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDL 470 480 490 500 510 520 460 470 480 490 500 510 pF1KSD GLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPG 530 540 550 560 570 580 520 530 540 550 560 570 pF1KSD VPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELS 590 600 610 620 630 640 580 590 600 610 620 630 pF1KSD AHATPAFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AHATPAFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKG 650 660 670 680 690 700 640 650 660 670 680 690 pF1KSD TNVWVALYKNNVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSDQANGLYSTEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TNVWVALYKNNVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSDQANGLYSTEY 710 720 730 740 750 760 700 pF1KSD IHSSFSGFLLCPT ::::::::::::: XP_005 IHSSFSGFLLCPT 770 780 >>NP_001281276 (OMIM: 120252,136800,609140) collagen alp (638 aa) initn: 4789 init1: 4789 opt: 4789 Z-score: 1721.0 bits: 328.8 E(85289): 4e-89 Smith-Waterman score: 4789; 100.0% identity (100.0% similar) in 638 aa overlap (66-703:1-638) 40 50 60 70 80 90 pF1KSD AGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPG :::::::::::::::::::::::::::::: NP_001 MPLPLLPMDLKGEPGPPGKPGPRGPPGPPG 10 20 30 100 110 120 130 140 150 pF1KSD FPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLR 40 50 60 70 80 90 160 170 180 190 200 210 pF1KSD GPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGL 100 110 120 130 140 150 220 230 240 250 260 270 pF1KSD PGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPP 160 170 180 190 200 210 280 290 300 310 320 330 pF1KSD GVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGL 220 230 240 250 260 270 340 350 360 370 380 390 pF1KSD LGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGD 280 290 300 310 320 330 400 410 420 430 440 450 pF1KSD QGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQ 340 350 360 370 380 390 460 470 480 490 500 510 pF1KSD PGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSP 400 410 420 430 440 450 520 530 540 550 560 570 pF1KSD GITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATP 460 470 480 490 500 510 580 590 600 610 620 630 pF1KSD AFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWV 520 530 540 550 560 570 640 650 660 670 680 690 pF1KSD ALYKNNVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALYKNNVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSF 580 590 600 610 620 630 700 pF1KSD SGFLLCPT :::::::: NP_001 SGFLLCPT >>NP_065084 (OMIM: 120251) collagen alpha-1(VIII) chain (744 aa) initn: 5240 init1: 2003 opt: 2644 Z-score: 962.1 bits: 188.6 E(85289): 7.5e-47 Smith-Waterman score: 2644; 57.2% identity (71.1% similar) in 671 aa overlap (42-702:88-743) 20 30 40 50 60 70 pF1KSD LLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGP-VGPPFREGKGQYLEMPLPL .:.. .: .: .: ::. :.:: NP_065 VPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGK--EIPLA- 60 70 80 90 100 110 80 90 100 110 120 130 pF1KSD LPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGL .:.:: :: :.:::::::::::.::. : ::..:.::: : :: .:: : ::. NP_065 ---SLRGEQGPRGEPGPRGPPGPPGLPGH---GIPGIKGKPGPQGYPG---VGKPGMPGM 120 130 140 150 160 140 150 160 170 180 190 pF1KSD PGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEP ::: : :.:: .:: : .:. : : ::: : ::: :. ::::. :.:: :: .:. NP_065 PGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDR 170 180 190 200 210 220 200 210 220 230 240 250 pF1KSD GPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGD ::.: ::: : :: :::.: :.:: ::. : : :::: : :.::::. :.:: : NP_065 GPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGP 230 240 250 260 270 280 260 270 280 290 300 pF1KSD KGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGE---PGTRGPP :. : :: :::.: :. : .::::. :.: :: :.:: : :.::: :: ::: NP_065 LGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPP 290 300 310 320 330 340 310 320 330 340 350 360 pF1KSD GLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAG :: : : : ::.:::::::: .:::: :: ::: : : :: :: : : ::.:: : NP_065 GL--P-GIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMG 350 360 370 380 390 400 370 380 390 400 410 420 pF1KSD LPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKG :: : ::::::.: :: : :: .:. : .:. :::: :: : :: .: ::: :::: NP_065 PPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKG 410 420 430 440 450 460 430 440 450 460 470 480 pF1KSD EPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPG : : : :: ::: : :: ::. :.::. ::.:: ::::. ::.::::: :.:: ::::: NP_065 EAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPG 470 480 490 500 510 520 490 500 510 520 530 540 pF1KSD LPGPPGEGRAGEPGTAGPTGPPGVPGSPGITG-P--PGPPGPPGPPGAPGAFDETGIA-G :::::: :.::.:: :::: ::. : : : ::::::::::: :... : : NP_065 LPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQG 530 540 550 560 570 580 550 560 570 580 590 600 pF1KSD LHLPN-G-GVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYNG .::. : :..:. .. . : . :. ::::: ::.::: : ::::.. :::: NP_065 EYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNG 590 600 610 620 630 640 610 620 630 640 650 660 pF1KSD HSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQASG ...::: :::::: : :::::::::: :: ::::::.::: :. :::::::::.:::::: NP_065 RQNYNPQTGIFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASG 650 660 670 680 690 700 670 680 690 700 pF1KSD GAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCPT .::: :::.:.:..::::.:: :::. .:.::::::.:: : NP_065 SAVLLLRPGDRVFLQMPSEQAAGLYAGQYVHSSFSGYLLYPM 710 720 730 740 >>NP_001841 (OMIM: 120251) collagen alpha-1(VIII) chain (744 aa) initn: 5240 init1: 2003 opt: 2644 Z-score: 962.1 bits: 188.6 E(85289): 7.5e-47 Smith-Waterman score: 2644; 57.2% identity (71.1% similar) in 671 aa overlap (42-702:88-743) 20 30 40 50 60 70 pF1KSD LLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGP-VGPPFREGKGQYLEMPLPL .:.. .: .: .: ::. :.:: NP_001 VPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQPAPRMGKEAVPKKGK--EIPLA- 60 70 80 90 100 110 80 90 100 110 120 130 pF1KSD LPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGL .:.:: :: :.:::::::::::.::. : ::..:.::: : :: .:: : ::. NP_001 ---SLRGEQGPRGEPGPRGPPGPPGLPGH---GIPGIKGKPGPQGYPG---VGKPGMPGM 120 130 140 150 160 140 150 160 170 180 190 pF1KSD PGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEP ::: : :.:: .:: : .:. : : ::: : ::: :. ::::. :.:: :: .:. NP_001 PGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDR 170 180 190 200 210 220 200 210 220 230 240 250 pF1KSD GPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGD ::.: ::: : :: :::.: :.:: ::. : : :::: : :.::::. :.:: : NP_001 GPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGP 230 240 250 260 270 280 260 270 280 290 300 pF1KSD KGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGE---PGTRGPP :. : :: :::.: :. : .::::. :.: :: :.:: : :.::: :: ::: NP_001 LGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPP 290 300 310 320 330 340 310 320 330 340 350 360 pF1KSD GLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAG :: : : : ::.:::::::: .:::: :: ::: : : :: :: : : ::.:: : NP_001 GL--P-GIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMG 350 360 370 380 390 400 370 380 390 400 410 420 pF1KSD LPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKG :: : ::::::.: :: : :: .:. : .:. :::: :: : :: .: ::: :::: NP_001 PPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKG 410 420 430 440 450 460 430 440 450 460 470 480 pF1KSD EPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPG : : : :: ::: : :: ::. :.::. ::.:: ::::. ::.::::: :.:: ::::: NP_001 EAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPG 470 480 490 500 510 520 490 500 510 520 530 540 pF1KSD LPGPPGEGRAGEPGTAGPTGPPGVPGSPGITG-P--PGPPGPPGPPGAPGAFDETGIA-G :::::: :.::.:: :::: ::. : : : ::::::::::: :... : : NP_001 LPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQG 530 540 550 560 570 580 550 560 570 580 590 600 pF1KSD LHLPN-G-GVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGMPVKFDRTLYNG .::. : :..:. .. . : . :. ::::: ::.::: : ::::.. :::: NP_001 EYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNG 590 600 610 620 630 640 610 620 630 640 650 660 pF1KSD HSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQASG ...::: :::::: : :::::::::: :: ::::::.::: :. :::::::::.:::::: NP_001 RQNYNPQTGIFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASG 650 660 670 680 690 700 670 680 690 700 pF1KSD GAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLLCPT .::: :::.:.:..::::.:: :::. .:.::::::.:: : NP_001 SAVLLLRPGDRVFLQMPSEQAAGLYAGQYVHSSFSGYLLYPM 710 720 730 740 >>XP_011533734 (OMIM: 120110,156500) PREDICTED: collagen (680 aa) initn: 3592 init1: 1912 opt: 2503 Z-score: 912.8 bits: 179.3 E(85289): 4.2e-44 Smith-Waterman score: 2503; 55.5% identity (69.9% similar) in 632 aa overlap (76-702:59-679) 50 60 70 80 90 100 pF1KSD PMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKP .: ::::: :::: ::: : :::::.:.: XP_011 TGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSP 30 40 50 60 70 80 110 120 130 140 150 160 pF1KSD GLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPG ::.:.:: :::: : .:: : :::::: : : : .:. : : : ::::::::.:: XP_011 GLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPG 90 100 110 120 130 140 170 180 190 200 210 220 pF1KSD PSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAP :.::..::::: :: : :: .: :: .: :: :: : ::. : : :: :: : : XP_011 PAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQ 150 160 170 180 190 200 230 240 250 260 270 280 pF1KSD GPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGA :: : :: :.:: : .:.:: :: ::. : :: :: : :: :: : : .:.: ::: XP_011 GPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGA 210 220 230 240 250 260 290 300 310 320 330 340 pF1KSD AGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGED :: :: : :.:: ::. : : :: :.: ::::: ::.:::::.:: : .:: : XP_011 AGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPA 270 280 290 300 310 320 350 360 370 380 390 400 pF1KSD GEPGEQGPQGLGGPPGL--P-GSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLA : ::. : :: :::: : : :.:: .: ::::::.::.:: : :: .:..: : XP_011 GLPGK--P-GLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSD 330 340 350 360 370 380 410 420 430 440 450 460 pF1KSD GKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPS :::: ::. :: : .: :: ::::.:: : :: :: .: : :: : :. : :: XP_011 GKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAP 390 400 410 420 430 440 470 480 490 500 510 520 pF1KSD GIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPG :::: .:: :: : :.:: ::.:: ::::: . . : ::::::: :: : .: :: XP_011 GIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPG 450 460 470 480 490 500 530 540 550 560 570 580 pF1KSD PPGPPGPPGAPGAFDETGIAGLHLPNGGVE-GAVLGKGGKPQFGLGE-LSAHATPAFTAV :::::::: :: .. .:.: .. : . .: : . .. ... . :::.. XP_011 LPGPPGPPGPPGQ----AV----MPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSAFTVI 510 520 530 540 550 590 600 610 620 630 640 pF1KSD LTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKN :.. .:: : :. ::. ::: .. :.: :::::: . :.:::.::::::::.:::.:::: XP_011 LSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFSYHVHVKGTHVWVGLYKN 560 570 580 590 600 610 650 660 670 680 690 700 pF1KSD NVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLL ..:. :::::: :::::::::.:...: :::::.:.:. ..:::::.::.::::::::. XP_011 GTPVMYTYDEYTKGYLDQASGSAIIDLTENDQVWLQLPNAESNGLYSSEYVHSSFSGFLV 620 630 640 650 660 670 pF1KSD CPT : XP_011 APM 680 >>NP_000484 (OMIM: 120110,156500) collagen alpha-1(X) ch (680 aa) initn: 3592 init1: 1912 opt: 2503 Z-score: 912.8 bits: 179.3 E(85289): 4.2e-44 Smith-Waterman score: 2503; 55.5% identity (69.9% similar) in 632 aa overlap (76-702:59-679) 50 60 70 80 90 100 pF1KSD PMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKP .: ::::: :::: ::: : :::::.:.: NP_000 TGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSP 30 40 50 60 70 80 110 120 130 140 150 160 pF1KSD GLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPG ::.:.:: :::: : .:: : :::::: : : : .:. : : : ::::::::.:: NP_000 GLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPG 90 100 110 120 130 140 170 180 190 200 210 220 pF1KSD PSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAP :.::..::::: :: : :: .: :: .: :: :: : ::. : : :: :: : : NP_000 PAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQ 150 160 170 180 190 200 230 240 250 260 270 280 pF1KSD GPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGA :: : :: :.:: : .:.:: :: ::. : :: :: : :: :: : : .:.: ::: NP_000 GPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGA 210 220 230 240 250 260 290 300 310 320 330 340 pF1KSD AGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGED :: :: : :.:: ::. : : :: :.: ::::: ::.:::::.:: : .:: : NP_000 AGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPA 270 280 290 300 310 320 350 360 370 380 390 400 pF1KSD GEPGEQGPQGLGGPPGL--P-GSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLA : ::. : :: :::: : : :.:: .: ::::::.::.:: : :: .:..: : NP_000 GLPGK--P-GLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSD 330 340 350 360 370 380 410 420 430 440 450 460 pF1KSD GKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPS :::: ::. :: : .: :: ::::.:: : :: :: .: : :: : :. : :: NP_000 GKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAP 390 400 410 420 430 440 470 480 490 500 510 520 pF1KSD GIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPG :::: .:: :: : :.:: ::.:: ::::: . . : ::::::: :: : .: :: NP_000 GIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPG 450 460 470 480 490 500 530 540 550 560 570 580 pF1KSD PPGPPGPPGAPGAFDETGIAGLHLPNGGVE-GAVLGKGGKPQFGLGE-LSAHATPAFTAV :::::::: :: .. .:.: .. : . .: : . .. ... . :::.. NP_000 LPGPPGPPGPPGQ----AV----MPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSAFTVI 510 520 530 540 550 590 600 610 620 630 640 pF1KSD LTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKN :.. .:: : :. ::. ::: .. :.: :::::: . :.:::.::::::::.:::.:::: NP_000 LSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFSYHVHVKGTHVWVGLYKN 560 570 580 590 600 610 650 660 670 680 690 700 pF1KSD NVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLL ..:. :::::: :::::::::.:...: :::::.:.:. ..:::::.::.::::::::. NP_000 GTPVMYTYDEYTKGYLDQASGSAIIDLTENDQVWLQLPNAESNGLYSSEYVHSSFSGFLV 620 630 640 650 660 670 pF1KSD CPT : NP_000 APM 680 >>XP_016865737 (OMIM: 120110,156500) PREDICTED: collagen (680 aa) initn: 3592 init1: 1912 opt: 2503 Z-score: 912.8 bits: 179.3 E(85289): 4.2e-44 Smith-Waterman score: 2503; 55.5% identity (69.9% similar) in 632 aa overlap (76-702:59-679) 50 60 70 80 90 100 pF1KSD PMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKP .: ::::: :::: ::: : :::::.:.: XP_016 TGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSP 30 40 50 60 70 80 110 120 130 140 150 160 pF1KSD GLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPG ::.:.:: :::: : .:: : :::::: : : : .:. : : : ::::::::.:: XP_016 GLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPG 90 100 110 120 130 140 170 180 190 200 210 220 pF1KSD PSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAP :.::..::::: :: : :: .: :: .: :: :: : ::. : : :: :: : : XP_016 PAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQ 150 160 170 180 190 200 230 240 250 260 270 280 pF1KSD GPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGA :: : :: :.:: : .:.:: :: ::. : :: :: : :: :: : : .:.: ::: XP_016 GPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGA 210 220 230 240 250 260 290 300 310 320 330 340 pF1KSD AGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGED :: :: : :.:: ::. : : :: :.: ::::: ::.:::::.:: : .:: : XP_016 AGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPA 270 280 290 300 310 320 350 360 370 380 390 400 pF1KSD GEPGEQGPQGLGGPPGL--P-GSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLA : ::. : :: :::: : : :.:: .: ::::::.::.:: : :: .:..: : XP_016 GLPGK--P-GLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSD 330 340 350 360 370 380 410 420 430 440 450 460 pF1KSD GKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPS :::: ::. :: : .: :: ::::.:: : :: :: .: : :: : :. : :: XP_016 GKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAP 390 400 410 420 430 440 470 480 490 500 510 520 pF1KSD GIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPG :::: .:: :: : :.:: ::.:: ::::: . . : ::::::: :: : .: :: XP_016 GIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPG 450 460 470 480 490 500 530 540 550 560 570 580 pF1KSD PPGPPGPPGAPGAFDETGIAGLHLPNGGVE-GAVLGKGGKPQFGLGE-LSAHATPAFTAV :::::::: :: .. .:.: .. : . .: : . .. ... . :::.. XP_016 LPGPPGPPGPPGQ----AV----MPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSAFTVI 510 520 530 540 550 590 600 610 620 630 640 pF1KSD LTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKN :.. .:: : :. ::. ::: .. :.: :::::: . :.:::.::::::::.:::.:::: XP_016 LSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFSYHVHVKGTHVWVGLYKN 560 570 580 590 600 610 650 660 670 680 690 700 pF1KSD NVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLL ..:. :::::: :::::::::.:...: :::::.:.:. ..:::::.::.::::::::. XP_016 GTPVMYTYDEYTKGYLDQASGSAIIDLTENDQVWLQLPNAESNGLYSSEYVHSSFSGFLV 620 630 640 650 660 670 pF1KSD CPT : XP_016 APM 680 >>XP_011533735 (OMIM: 120110,156500) PREDICTED: collagen (680 aa) initn: 3592 init1: 1912 opt: 2503 Z-score: 912.8 bits: 179.3 E(85289): 4.2e-44 Smith-Waterman score: 2503; 55.5% identity (69.9% similar) in 632 aa overlap (76-702:59-679) 50 60 70 80 90 100 pF1KSD PMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKP .: ::::: :::: ::: : :::::.:.: XP_011 TGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSP 30 40 50 60 70 80 110 120 130 140 150 160 pF1KSD GLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPG ::.:.:: :::: : .:: : :::::: : : : .:. : : : ::::::::.:: XP_011 GLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPG 90 100 110 120 130 140 170 180 190 200 210 220 pF1KSD PSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAP :.::..::::: :: : :: .: :: .: :: :: : ::. : : :: :: : : XP_011 PAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQ 150 160 170 180 190 200 230 240 250 260 270 280 pF1KSD GPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGA :: : :: :.:: : .:.:: :: ::. : :: :: : :: :: : : .:.: ::: XP_011 GPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGA 210 220 230 240 250 260 290 300 310 320 330 340 pF1KSD AGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGED :: :: : :.:: ::. : : :: :.: ::::: ::.:::::.:: : .:: : XP_011 AGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPA 270 280 290 300 310 320 350 360 370 380 390 400 pF1KSD GEPGEQGPQGLGGPPGL--P-GSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLA : ::. : :: :::: : : :.:: .: ::::::.::.:: : :: .:..: : XP_011 GLPGK--P-GLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSD 330 340 350 360 370 380 410 420 430 440 450 460 pF1KSD GKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPS :::: ::. :: : .: :: ::::.:: : :: :: .: : :: : :. : :: XP_011 GKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAP 390 400 410 420 430 440 470 480 490 500 510 520 pF1KSD GIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPG :::: .:: :: : :.:: ::.:: ::::: . . : ::::::: :: : .: :: XP_011 GIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPG 450 460 470 480 490 500 530 540 550 560 570 580 pF1KSD PPGPPGPPGAPGAFDETGIAGLHLPNGGVE-GAVLGKGGKPQFGLGE-LSAHATPAFTAV :::::::: :: .. .:.: .. : . .: : . .. ... . :::.. XP_011 LPGPPGPPGPPGQ----AV----MPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSAFTVI 510 520 530 540 550 590 600 610 620 630 640 pF1KSD LTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKN :.. .:: : :. ::. ::: .. :.: :::::: . :.:::.::::::::.:::.:::: XP_011 LSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFSYHVHVKGTHVWVGLYKN 560 570 580 590 600 610 650 660 670 680 690 700 pF1KSD NVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLL ..:. :::::: :::::::::.:...: :::::.:.:. ..:::::.::.::::::::. XP_011 GTPVMYTYDEYTKGYLDQASGSAIIDLTENDQVWLQLPNAESNGLYSSEYVHSSFSGFLV 620 630 640 650 660 670 pF1KSD CPT : XP_011 APM 680 >>XP_006715396 (OMIM: 120110,156500) PREDICTED: collagen (680 aa) initn: 3592 init1: 1912 opt: 2503 Z-score: 912.8 bits: 179.3 E(85289): 4.2e-44 Smith-Waterman score: 2503; 55.5% identity (69.9% similar) in 632 aa overlap (76-702:59-679) 50 60 70 80 90 100 pF1KSD PMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKP .: ::::: :::: ::: : :::::.:.: XP_006 TGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSP 30 40 50 60 70 80 110 120 130 140 150 160 pF1KSD GLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPG ::.:.:: :::: : .:: : :::::: : : : .:. : : : ::::::::.:: XP_006 GLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPG 90 100 110 120 130 140 170 180 190 200 210 220 pF1KSD PSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAP :.::..::::: :: : :: .: :: .: :: :: : ::. : : :: :: : : XP_006 PAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQ 150 160 170 180 190 200 230 240 250 260 270 280 pF1KSD GPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGA :: : :: :.:: : .:.:: :: ::. : :: :: : :: :: : : .:.: ::: XP_006 GPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGA 210 220 230 240 250 260 290 300 310 320 330 340 pF1KSD AGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPGED :: :: : :.:: ::. : : :: :.: ::::: ::.:::::.:: : .:: : XP_006 AGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPA 270 280 290 300 310 320 350 360 370 380 390 400 pF1KSD GEPGEQGPQGLGGPPGL--P-GSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLA : ::. : :: :::: : : :.:: .: ::::::.::.:: : :: .:..: : XP_006 GLPGK--P-GLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSD 330 340 350 360 370 380 410 420 430 440 450 460 pF1KSD GKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPS :::: ::. :: : .: :: ::::.:: : :: :: .: : :: : :. : :: XP_006 GKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAP 390 400 410 420 430 440 470 480 490 500 510 520 pF1KSD GIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPG :::: .:: :: : :.:: ::.:: ::::: . . : ::::::: :: : .: :: XP_006 GIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPG 450 460 470 480 490 500 530 540 550 560 570 580 pF1KSD PPGPPGPPGAPGAFDETGIAGLHLPNGGVE-GAVLGKGGKPQFGLGE-LSAHATPAFTAV :::::::: :: .. .:.: .. : . .: : . .. ... . :::.. XP_006 LPGPPGPPGPPGQ----AV----MPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSAFTVI 510 520 530 540 550 590 600 610 620 630 640 pF1KSD LTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVHVKGTNVWVALYKN :.. .:: : :. ::. ::: .. :.: :::::: . :.:::.::::::::.:::.:::: XP_006 LSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFSYHVHVKGTHVWVGLYKN 560 570 580 590 600 610 650 660 670 680 690 700 pF1KSD NVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSDQANGLYSTEYIHSSFSGFLL ..:. :::::: :::::::::.:...: :::::.:.:. ..:::::.::.::::::::. XP_006 GTPVMYTYDEYTKGYLDQASGSAIIDLTENDQVWLQLPNAESNGLYSSEYVHSSFSGFLV 620 630 640 650 660 670 pF1KSD CPT : XP_006 APM 680 703 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 08:56:30 2016 done: Thu Nov 3 08:56:32 2016 Total Scan time: 14.930 Total Display time: 0.160 Function used was FASTA [36.3.4 Apr, 2011]