Result of FASTA (omim) for
pF1KSDF0258
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDF0258, 768 aa
1>>>pF1KSDF0258 768 - 768 aa - 768 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.5580+/-0.000342; mu= 6.9155+/- 0.022
mean_var=187.1350+/-37.763, 0's: 0 Z-trim(120.4): 63 B-trim: 432 in 1/56
Lambda= 0.093755
statistics sampled from 35479 (35542) to 35479 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.736), E-opt: 0.2 (0.417), width: 16
Scan time: 14.090
The best scores are: opt bits E(85289)
NP_689619 (OMIM: 614410) actin filament-associated ( 768) 5125 705.9 1.7e-202
XP_016864525 (OMIM: 614410) PREDICTED: actin filam ( 734) 4913 677.2 6.9e-194
NP_001139809 (OMIM: 614410) actin filament-associa ( 725) 4800 661.9 2.7e-189
XP_011535860 (OMIM: 614410) PREDICTED: actin filam ( 628) 4148 573.6 8.5e-163
NP_001309991 (OMIM: 614410) actin filament-associa ( 735) 3948 546.6 1.3e-154
NP_001309992 (OMIM: 614410) actin filament-associa ( 377) 2292 322.5 2.1e-87
NP_940997 (OMIM: 608252) actin filament-associated ( 730) 1460 210.1 2.7e-53
XP_006713972 (OMIM: 608252) PREDICTED: actin filam ( 751) 1460 210.1 2.8e-53
XP_016864025 (OMIM: 608252) PREDICTED: actin filam ( 555) 1455 209.4 3.5e-53
XP_016864024 (OMIM: 608252) PREDICTED: actin filam ( 748) 1455 209.4 4.4e-53
XP_011511846 (OMIM: 608252) PREDICTED: actin filam ( 814) 1455 209.5 4.7e-53
NP_001128119 (OMIM: 608252) actin filament-associa ( 814) 1455 209.5 4.7e-53
XP_016872313 (OMIM: 612420) PREDICTED: actin filam ( 759) 740 112.7 5.8e-24
XP_016872311 (OMIM: 612420) PREDICTED: actin filam ( 785) 740 112.7 5.9e-24
XP_016872317 (OMIM: 612420) PREDICTED: actin filam ( 731) 704 107.8 1.6e-22
XP_016872312 (OMIM: 612420) PREDICTED: actin filam ( 763) 641 99.3 6.2e-20
XP_016872308 (OMIM: 612420) PREDICTED: actin filam ( 789) 641 99.3 6.4e-20
XP_016872307 (OMIM: 612420) PREDICTED: actin filam ( 803) 641 99.4 6.5e-20
XP_016872304 (OMIM: 612420) PREDICTED: actin filam ( 829) 641 99.4 6.7e-20
XP_016872319 (OMIM: 612420) PREDICTED: actin filam ( 679) 605 94.4 1.7e-18
XP_016872316 (OMIM: 612420) PREDICTED: actin filam ( 735) 605 94.5 1.8e-18
NP_001274753 (OMIM: 612420) actin filament-associa ( 871) 578 90.9 2.5e-17
XP_016872310 (OMIM: 612420) PREDICTED: actin filam ( 785) 559 88.3 1.4e-16
XP_016872309 (OMIM: 612420) PREDICTED: actin filam ( 786) 559 88.3 1.4e-16
XP_016872303 (OMIM: 612420) PREDICTED: actin filam ( 830) 559 88.3 1.5e-16
XP_016872298 (OMIM: 612420) PREDICTED: actin filam ( 841) 559 88.3 1.5e-16
XP_016872297 (OMIM: 612420) PREDICTED: actin filam ( 842) 559 88.3 1.5e-16
XP_016872295 (OMIM: 612420) PREDICTED: actin filam ( 845) 559 88.3 1.5e-16
XP_016872294 (OMIM: 612420) PREDICTED: actin filam ( 846) 559 88.3 1.5e-16
XP_016872292 (OMIM: 612420) PREDICTED: actin filam ( 867) 559 88.3 1.5e-16
XP_016872291 (OMIM: 612420) PREDICTED: actin filam ( 868) 559 88.3 1.5e-16
XP_016872290 (OMIM: 612420) PREDICTED: actin filam ( 871) 559 88.3 1.5e-16
XP_016872289 (OMIM: 612420) PREDICTED: actin filam ( 872) 559 88.3 1.5e-16
XP_016872288 (OMIM: 612420) PREDICTED: actin filam ( 881) 559 88.3 1.5e-16
XP_016872287 (OMIM: 612420) PREDICTED: actin filam ( 882) 559 88.3 1.5e-16
XP_016872286 (OMIM: 612420) PREDICTED: actin filam ( 885) 559 88.3 1.5e-16
XP_016872285 (OMIM: 612420) PREDICTED: actin filam ( 886) 559 88.3 1.5e-16
XP_016872284 (OMIM: 612420) PREDICTED: actin filam ( 904) 559 88.3 1.6e-16
XP_016872283 (OMIM: 612420) PREDICTED: actin filam ( 908) 559 88.3 1.6e-16
XP_016872282 (OMIM: 612420) PREDICTED: actin filam ( 911) 559 88.3 1.6e-16
XP_016872281 (OMIM: 612420) PREDICTED: actin filam ( 912) 559 88.3 1.6e-16
XP_016872315 (OMIM: 612420) PREDICTED: actin filam ( 757) 523 83.4 3.9e-15
XP_016872314 (OMIM: 612420) PREDICTED: actin filam ( 758) 523 83.4 4e-15
XP_016872321 (OMIM: 612420) PREDICTED: actin filam ( 795) 523 83.4 4.1e-15
XP_005270298 (OMIM: 612420) PREDICTED: actin filam ( 802) 523 83.4 4.1e-15
XP_016872306 (OMIM: 612420) PREDICTED: actin filam ( 813) 523 83.4 4.2e-15
NP_115939 (OMIM: 612420) actin filament-associated ( 814) 523 83.4 4.2e-15
XP_016872305 (OMIM: 612420) PREDICTED: actin filam ( 817) 523 83.4 4.2e-15
NP_001001936 (OMIM: 612420) actin filament-associa ( 818) 523 83.4 4.2e-15
XP_016872302 (OMIM: 612420) PREDICTED: actin filam ( 831) 523 83.4 4.3e-15
>>NP_689619 (OMIM: 614410) actin filament-associated pro (768 aa)
initn: 5125 init1: 5125 opt: 5125 Z-score: 3756.6 bits: 705.9 E(85289): 1.7e-202
Smith-Waterman score: 5125; 100.0% identity (100.0% similar) in 768 aa overlap (1-768:1-768)
10 20 30 40 50 60
pF1KSD MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD PPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 PPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD DSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 DSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD TVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 TVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD REQAEEWLKVIREVSKPVGGAEGVEVPRSPVLLCKLDLDKRLSQEKQTSDSDSVGVGDNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 REQAEEWLKVIREVSKPVGGAEGVEVPRSPVLLCKLDLDKRLSQEKQTSDSDSVGVGDNC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD STLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTEEEVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 STLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTEEEVP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD CCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPRHPFAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 CCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPRHPFAF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD RILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSAGRNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 RILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSAGRNS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD FLYARSCQNQWPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 FLYARSCQNQWPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD HASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 HASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD KLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 KLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGET
670 680 690 700 710 720
730 740 750 760
pF1KSD ANKPQNSVPEQPLPVNCVSELRKRSPSIVASNQGRVLQKAKEWEMKKT
::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 ANKPQNSVPEQPLPVNCVSELRKRSPSIVASNQGRVLQKAKEWEMKKT
730 740 750 760
>>XP_016864525 (OMIM: 614410) PREDICTED: actin filament- (734 aa)
initn: 4913 init1: 4913 opt: 4913 Z-score: 3601.9 bits: 677.2 E(85289): 6.9e-194
Smith-Waterman score: 4913; 100.0% identity (100.0% similar) in 734 aa overlap (35-768:1-734)
10 20 30 40 50 60
pF1KSD QVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTADLHS
::::::::::::::::::::::::::::::
XP_016 MAVASILQSLQPLPAKEVSYLYVNTADLHS
10 20 30
70 80 90 100 110 120
pF1KSD GPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNKPPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNKPPPE
40 50 60 70 80 90
130 140 150 160 170 180
pF1KSD DYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYNDSDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYNDSDA
100 110 120 130 140 150
190 200 210 220 230 240
pF1KSD MSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQLTVIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQLTVIR
160 170 180 190 200 210
250 260 270 280 290 300
pF1KSD EDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQSREQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQSREQA
220 230 240 250 260 270
310 320 330 340 350 360
pF1KSD EEWLKVIREVSKPVGGAEGVEVPRSPVLLCKLDLDKRLSQEKQTSDSDSVGVGDNCSTLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEWLKVIREVSKPVGGAEGVEVPRSPVLLCKLDLDKRLSQEKQTSDSDSVGVGDNCSTLG
280 290 300 310 320 330
370 380 390 400 410 420
pF1KSD RRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTEEEVPCCGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTEEEVPCCGY
340 350 360 370 380 390
430 440 450 460 470 480
pF1KSD LNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPRHPFAFRILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPRHPFAFRILR
400 410 420 430 440 450
490 500 510 520 530 540
pF1KSD NRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSAGRNSFLYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSAGRNSFLYA
460 470 480 490 500 510
550 560 570 580 590 600
pF1KSD RSCQNQWPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKRHASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSCQNQWPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKRHASS
520 530 540 550 560 570
610 620 630 640 650 660
pF1KSD ANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKA
580 590 600 610 620 630
670 680 690 700 710 720
pF1KSD LEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGETANKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGETANKP
640 650 660 670 680 690
730 740 750 760
pF1KSD QNSVPEQPLPVNCVSELRKRSPSIVASNQGRVLQKAKEWEMKKT
::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNSVPEQPLPVNCVSELRKRSPSIVASNQGRVLQKAKEWEMKKT
700 710 720 730
>>NP_001139809 (OMIM: 614410) actin filament-associated (725 aa)
initn: 4800 init1: 4800 opt: 4800 Z-score: 3519.4 bits: 661.9 E(85289): 2.7e-189
Smith-Waterman score: 4800; 100.0% identity (100.0% similar) in 719 aa overlap (1-719:1-719)
10 20 30 40 50 60
pF1KSD MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD PPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD DSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD TVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD REQAEEWLKVIREVSKPVGGAEGVEVPRSPVLLCKLDLDKRLSQEKQTSDSDSVGVGDNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REQAEEWLKVIREVSKPVGGAEGVEVPRSPVLLCKLDLDKRLSQEKQTSDSDSVGVGDNC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD STLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTEEEVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTEEEVP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD CCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPRHPFAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPRHPFAF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD RILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSAGRNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSAGRNS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD FLYARSCQNQWPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLYARSCQNQWPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD HASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD KLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGET
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGEW
670 680 690 700 710 720
730 740 750 760
pF1KSD ANKPQNSVPEQPLPVNCVSELRKRSPSIVASNQGRVLQKAKEWEMKKT
NP_001 EMKKT
>>XP_011535860 (OMIM: 614410) PREDICTED: actin filament- (628 aa)
initn: 4148 init1: 4148 opt: 4148 Z-score: 3043.7 bits: 573.6 E(85289): 8.5e-163
Smith-Waterman score: 4148; 99.8% identity (100.0% similar) in 623 aa overlap (146-768:6-628)
120 130 140 150 160 170
pF1KSD PLPNKPPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGEL
.:::::::::::::::::::::::::::::
XP_011 MVLGSDGCSPSHSIVDGYYEDADSSYPATRVNGEL
10 20 30
180 190 200 210 220 230
pF1KSD KSSYNDSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSSYNDSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQ
40 50 60 70 80 90
240 250 260 270 280 290
pF1KSD WAKQLTVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WAKQLTVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLV
100 110 120 130 140 150
300 310 320 330 340 350
pF1KSD LALQSREQAEEWLKVIREVSKPVGGAEGVEVPRSPVLLCKLDLDKRLSQEKQTSDSDSVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LALQSREQAEEWLKVIREVSKPVGGAEGVEVPRSPVLLCKLDLDKRLSQEKQTSDSDSVG
160 170 180 190 200 210
360 370 380 390 400 410
pF1KSD VGDNCSTLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGDNCSTLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSST
220 230 240 250 260 270
420 430 440 450 460 470
pF1KSD EEEVPCCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEVPCCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPR
280 290 300 310 320 330
480 490 500 510 520 530
pF1KSD HPFAFRILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPFAFRILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVS
340 350 360 370 380 390
540 550 560 570 580 590
pF1KSD AGRNSFLYARSCQNQWPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGRNSFLYARSCQNQWPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQ
400 410 420 430 440 450
600 610 620 630 640 650
pF1KSD VKVKRHASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKVKRHASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIR
460 470 480 490 500 510
660 670 680 690 700 710
pF1KSD SSPGAKLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPGAKLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKP
520 530 540 550 560 570
720 730 740 750 760
pF1KSD KSGETANKPQNSVPEQPLPVNCVSELRKRSPSIVASNQGRVLQKAKEWEMKKT
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSGETANKPQNSVPEQPLPVNCVSELRKRSPSIVASNQGRVLQKAKEWEMKKT
580 590 600 610 620
>>NP_001309991 (OMIM: 614410) actin filament-associated (735 aa)
initn: 3925 init1: 3925 opt: 3948 Z-score: 2896.5 bits: 546.6 E(85289): 1.3e-154
Smith-Waterman score: 4824; 95.7% identity (95.7% similar) in 768 aa overlap (1-768:1-735)
10 20 30 40 50 60
pF1KSD MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD PPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYN
:::::::::::::::::::::::::: :
NP_001 PPPEDYYEEALPLGPGKSPEYISSHN---------------------------------N
130 140
190 200 210 220 230 240
pF1KSD DSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQL
150 160 170 180 190 200
250 260 270 280 290 300
pF1KSD TVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQS
210 220 230 240 250 260
310 320 330 340 350 360
pF1KSD REQAEEWLKVIREVSKPVGGAEGVEVPRSPVLLCKLDLDKRLSQEKQTSDSDSVGVGDNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REQAEEWLKVIREVSKPVGGAEGVEVPRSPVLLCKLDLDKRLSQEKQTSDSDSVGVGDNC
270 280 290 300 310 320
370 380 390 400 410 420
pF1KSD STLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTEEEVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTEEEVP
330 340 350 360 370 380
430 440 450 460 470 480
pF1KSD CCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPRHPFAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPRHPFAF
390 400 410 420 430 440
490 500 510 520 530 540
pF1KSD RILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSAGRNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSAGRNS
450 460 470 480 490 500
550 560 570 580 590 600
pF1KSD FLYARSCQNQWPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLYARSCQNQWPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQVKVKR
510 520 530 540 550 560
610 620 630 640 650 660
pF1KSD HASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGA
570 580 590 600 610 620
670 680 690 700 710 720
pF1KSD KLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLKALEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGET
630 640 650 660 670 680
730 740 750 760
pF1KSD ANKPQNSVPEQPLPVNCVSELRKRSPSIVASNQGRVLQKAKEWEMKKT
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANKPQNSVPEQPLPVNCVSELRKRSPSIVASNQGRVLQKAKEWEMKKT
690 700 710 720 730
>>NP_001309992 (OMIM: 614410) actin filament-associated (377 aa)
initn: 2292 init1: 2292 opt: 2292 Z-score: 1690.1 bits: 322.5 E(85289): 2.1e-87
Smith-Waterman score: 2292; 100.0% identity (100.0% similar) in 340 aa overlap (1-340:1-340)
10 20 30 40 50 60
pF1KSD MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD PPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD DSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD TVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD REQAEEWLKVIREVSKPVGGAEGVEVPRSPVLLCKLDLDKRLSQEKQTSDSDSVGVGDNC
::::::::::::::::::::::::::::::::::::::::
NP_001 REQAEEWLKVIREVSKPVGGAEGVEVPRSPVLLCKLDLDKVYLSPLSLPQARQWPLNTGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD STLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTEEEVP
NP_001 TPGELTGWGESQATAKL
370
>>NP_940997 (OMIM: 608252) actin filament-associated pro (730 aa)
initn: 1785 init1: 679 opt: 1460 Z-score: 1077.8 bits: 210.1 E(85289): 2.7e-53
Smith-Waterman score: 2002; 44.6% identity (68.3% similar) in 796 aa overlap (7-766:1-727)
10 20 30 40 50 60
pF1KSD MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA
.:.:. :: .: :::::::..:. ::: ....:: .: . .:. .
NP_940 MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDVKDHAQKQE
10 20 30 40 50
70 80 90 100 110 120
pF1KSD DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK
.: :. : . ::. . : : . :::::..
NP_940 TANSLPA-------------------------PPQMPLPEIPQ-PWLPPDSG-PPPLPTS
60 70 80
130 140 150 160 170 180
pF1KSD PPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYN
:: :::::.::.:::.::::.:.
NP_940 SLPEGYYEEAVPLSPGKAPEYITSNY----------------------------------
90 100 110
190 200 210 220 230 240
pF1KSD DSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQL
:::::::::::::::::.::. . ::::::::::: ::.. .::::::::::::::.: :
NP_940 DSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWTKLL
120 130 140 150 160 170
250 260 270 280 290 300
pF1KSD TVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQS
::.. .:::::::::.::...: :. :.: :.::::..:.:::..:: .:. ::::.::
NP_940 CVIKDTKLLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKHELKITQQGTDPLVLAVQS
180 190 200 210 220 230
310 320 330 340 350
pF1KSD REQAEEWLKVIREVSKPVGGAEGVEVPRSPVL-LCKLDLDKRLSQEKQTSDSDSVGVGDN
.::::.:::::.:. . .: : : : . : .:.:.::.:. .::...: : ..
NP_940 KEQAEQWLKVIKEAYSGCSGPVDSECPPPPSSPVHKAELEKKLSSERPSSDGEGV-VENG
240 250 260 270 280 290
360 370 380 390 400 410
pF1KSD CSTLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTEEEV
.: . .: : :::: .: ::..:...:.:::.::...::: .:. ::::.::.:
NP_940 ITTCNGKEQV---KRKKSSKSEAKGTVSKVTGKKITKIISLGKKKPSTDE-QTSSAEEDV
300 310 320 330 340
420 430 440 450 460 470
pF1KSD PCCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPRHPFA
: ::::::: :. :.:::::.: : : ::::. ::.::. .: :.:::: ::. .::..
NP_940 PTCGYLNVLSNSRWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKHPLT
350 360 370 380 390 400
480 490 500 510 520 530
pF1KSD FRILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSAGRN
::.::: ::::.:::: :::::::.:.::.: :: . ::::::::.::: .:.......
NP_940 FRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALHYDYIDVEMSASVIQTAKQ
410 420 430 440 450 460
540 550 560 570 580
pF1KSD SFL-----------YARSCQNQWPEPRV----YDDVP--YEKMQDEEPERPTGAQVKRHA
.: : . .: . .: ::::: ... ..: ... : ..
NP_940 TFCFMNRRVISANPYLGGTSNGYAHPSGTALHYDDVPCINGSLKGKKPPVASNG-VTGKG
470 480 490 500 510 520
590 600 610 620 630 640
pF1KSD SSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIA
.. : . ...:: . ::: .:.: ::::::::.: ::.: ...:.: :.::..:..:
NP_940 KTLSSQPKKADPAAVVKRTGSNAAQYKYGKNRVEADAKRLQTKEEELLKRKEALRNRLAQ
530 540 550 560 570 580
650 660 670 680 690 700
pF1KSD LRQEKRELKEAIRSSPGAKLKA-LEEAVATLEAQCRAKEERRIDLELKLVAVKERLQQSL
::.:...:. ::. . : : .: ::: . :: .:: :: .:..:::.:. ::: :...:
NP_940 LRKERKDLRAAIEVNAGRKPQAILEEKLKQLEEECRQKEAERVSLELELTEVKESLKKAL
590 600 610 620 630 640
710 720 730 740
pF1KSD AGGPALGLSVSSKPKSGETA------------NKPQNSVP----EQPLPVNCVSELRKRS
::: .:::.. .:::: .. :.: .: : :.::: .. :.: .
NP_940 AGGVTLGLAI--EPKSGTSSPQSPVFRHRTLENSPISSCDTSDTEGPVPVNSAAVLKKSQ
650 660 670 680 690 700
750 760
pF1KSD PSIVASN-QGRVLQKAKEWEMKKT
. .: .:.::.::::::.:
NP_940 AAPGSSPCRGHVLRKAKEWELKNGT
710 720 730
>>XP_006713972 (OMIM: 608252) PREDICTED: actin filament- (751 aa)
initn: 1785 init1: 679 opt: 1460 Z-score: 1077.6 bits: 210.1 E(85289): 2.8e-53
Smith-Waterman score: 2003; 44.6% identity (68.6% similar) in 799 aa overlap (5-766:20-748)
10 20 30 40
pF1KSD MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQ
...:.:. :: .: :::::::..:. ::: ....:: .:
XP_006 MRFKQEHPHPRNEAKAVTVRAMEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KSD PLPAKEVSYLYVNTADLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSP
. .:. . .: :. : . ::. . :
XP_006 SSKGFDVKDHAQKQETANSLPA-------------------------PPQMPLPEIPQ-P
70 80 90
110 120 130 140 150 160
pF1KSD RLRNAADLPPPLPNKPPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSS
: . :::::.. :: :::::.::.:::.::::.:.
XP_006 WLPPDSG-PPPLPTSSLPEGYYEEAVPLSPGKAPEYITSNY-------------------
100 110 120 130
170 180 190 200 210 220
pF1KSD YPATRVNGELKSSYNDSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICA
:::::::::::::::::.::. . ::::::::::: ::.. .:::
XP_006 ---------------DSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICA
140 150 160 170
230 240 250 260 270 280
pF1KSD FLLRKKRFGQWAKQLTVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELR
:::::::::::.: : ::.. .:::::::::.::...: :. :.: :.::::..:.:::.
XP_006 FLLRKKRFGQWTKLLCVIKDTKLLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKHELK
180 190 200 210 220 230
290 300 310 320 330 340
pF1KSD FTQGATEVLVLALQSREQAEEWLKVIREVSKPVGGAEGVEVPRSPVL-LCKLDLDKRLSQ
.:: .:. ::::.::.::::.:::::.:. . .: : : : . : .:.:.::.
XP_006 ITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDSECPPPPSSPVHKAELEKKLSS
240 250 260 270 280 290
350 360 370 380 390 400
pF1KSD EKQTSDSDSVGVGDNCSTLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKK
:. .::...: : .. .: . .: : :::: .: ::..:...:.:::.::...:::
XP_006 ERPSSDGEGV-VENGITTCNGKEQV---KRKKSSKSEAKGTVSKVTGKKITKIISLGKKK
300 310 320 330 340 350
410 420 430 440 450 460
pF1KSD TLADDLQTSSTEEEVPCCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQ
.:. ::::.::.:: ::::::: :. :.:::::.: : : ::::. ::.::. .: :.
XP_006 PSTDE-QTSSAEEDVPTCGYLNVLSNSRWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLR
360 370 380 390 400 410
470 480 490 500 510 520
pF1KSD GCEVAPGFGPRHPFAFRILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDY
:::: ::. .::..::.::: ::::.:::: :::::::.:.::.: :: . ::::::::
XP_006 GCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALHYDY
420 430 440 450 460 470
530 540 550 560
pF1KSD VDVETLTSIVSAGRNSFL-----------YARSCQNQWPEPRV----YDDVP--YEKMQD
.::: .:........: : . .: . .: ::::: ...
XP_006 IDVEMSASVIQTAKQTFCFMNRRVISANPYLGGTSNGYAHPSGTALHYDDVPCINGSLKG
480 490 500 510 520 530
570 580 590 600 610 620
pF1KSD EEPERPTGAQ-VKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARRYLVEK
..: :.... : .... : . ...:: . ::: .:.: ::::::::.: ::.: ...
XP_006 KKP--PVASNGVTGKGKTLSSQPKKADPAAVVKRTGSNAAQYKYGKNRVEADAKRLQTKE
540 550 560 570 580 590
630 640 650 660 670 680
pF1KSD EKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKA-LEEAVATLEAQCRAKEERRID
:.: :.::..:..: ::.:...:. ::. . : : .: ::: . :: .:: :: .:..
XP_006 EELLKRKEALRNRLAQLRKERKDLRAAIEVNAGRKPQAILEEKLKQLEEECRQKEAERVS
600 610 620 630 640 650
690 700 710 720
pF1KSD LELKLVAVKERLQQSLAGGPALGLSVSSKPKSGETA------------NKPQNSVP----
:::.:. ::: :...:::: .:::.. .:::: .. :.: .:
XP_006 LELELTEVKESLKKALAGGVTLGLAI--EPKSGTSSPQSPVFRHRTLENSPISSCDTSDT
660 670 680 690 700 710
730 740 750 760
pF1KSD EQPLPVNCVSELRKRSPSIVASN-QGRVLQKAKEWEMKKT
: :.::: .. :.: . . .: .:.::.::::::.:
XP_006 EGPVPVNSAAVLKKSQAAPGSSPCRGHVLRKAKEWELKNGT
720 730 740 750
>>XP_016864025 (OMIM: 608252) PREDICTED: actin filament- (555 aa)
initn: 1484 init1: 679 opt: 1455 Z-score: 1075.9 bits: 209.4 E(85289): 3.5e-53
Smith-Waterman score: 1560; 45.8% identity (68.8% similar) in 583 aa overlap (7-585:1-506)
10 20 30 40 50
pF1KSD MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASIL---QSLQPLPAKEVSYLYV
.:.:. :: .: :::::::..:. ::: ....:: :: . . .:. .
XP_016 MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDVKDHAQKQE
10 20 30 40 50
60 70 80 90 100 110
pF1KSD NTADLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPL
.. .: . :.. : ..:. :..: ::::
XP_016 TANSLPAPPQM-------------PLPEIPQPWLPPDSG-----------------PPPL
60 70 80
120 130 140 150 160 170
pF1KSD PNKPPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKS
:.. :: :::::.::.:::.::::.:.
XP_016 PTSSLPEGYYEEAVPLSPGKAPEYITSNY-------------------------------
90 100 110
180 190 200 210 220 230
pF1KSD SYNDSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWA
:::::::::::::::::.::. . ::::::::::: ::.. .::::::::::::::.
XP_016 ---DSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWT
120 130 140 150 160 170
240 250 260 270 280 290
pF1KSD KQLTVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLA
: : ::.. .:::::::::.::...: :. :.: :.::::..:.:::..:: .:. ::::
XP_016 KLLCVIKDTKLLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKHELKITQQGTDPLVLA
180 190 200 210 220 230
300 310 320 330 340 350
pF1KSD LQSREQAEEWLKVIREVSKPVGGAEGVEVPRSPVL-LCKLDLDKRLSQEKQTSDSDSVGV
.::.::::.:::::.:. . .: : : : . : .:.:.::.:. .::...: :
XP_016 VQSKEQAEQWLKVIKEAYSGCSGPVDSECPPPPSSPVHKAELEKKLSSERPSSDGEGV-V
240 250 260 270 280
360 370 380 390 400 410
pF1KSD GDNCSTLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTE
.. .: . .: : :::: .: ::..:...:.:::.::...::: .:. ::::.:
XP_016 ENGITTCNGKEQV---KRKKSSKSEAKGTVSKVTGKKITKIISLGKKKPSTDE-QTSSAE
290 300 310 320 330 340
420 430 440 450 460 470
pF1KSD EEVPCCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPRH
:.:: ::::::: :. :.:::::.: : : ::::. ::.::. .: :.:::: ::. .:
XP_016 EDVPTCGYLNVLSNSRWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKH
350 360 370 380 390 400
480 490 500 510 520 530
pF1KSD PFAFRILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSA
:..::.::: ::::.:::: :::::::.:.::.: :: . ::::::::.::: .:....
XP_016 PLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALHYDYIDVEMSASVIQT
410 420 430 440 450 460
540 550 560 570 580 590
pF1KSD GRNSFLYARSCQNQWPEPRVYDDVPYEKMQDEEPERPTGAQVKRHASSCSEKSHRVDPQV
....: . .:. :: . :: .. .:.:. .. :
XP_016 AKQTFCF----MNR----RVISANPYLGGTSNGYAHPSGTALHYDDVPCINGSWEPEDGF
470 480 490 500 510
600 610 620 630 640 650
pF1KSD KVKRHASSANQYKYGKNRAEEDARRYLVEKEKLEKEKETIRTELIALRQEKRELKEAIRS
XP_016 PASCSRGLGEEVLYDNAGLSRVKSPPWRLMGSQEKGRL
520 530 540 550
>>XP_016864024 (OMIM: 608252) PREDICTED: actin filament- (748 aa)
initn: 1785 init1: 679 opt: 1455 Z-score: 1074.0 bits: 209.4 E(85289): 4.4e-53
Smith-Waterman score: 1918; 43.7% identity (66.9% similar) in 791 aa overlap (7-743:1-721)
10 20 30 40 50 60
pF1KSD MDRGQVLEQLLPELTGLLSLLDHEYLSDTTLEKKMAVASILQSLQPLPAKEVSYLYVNTA
.:.:. :: .: :::::::..:. ::: ....:: .: . .:. .
XP_016 MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDVKDHAQKQE
10 20 30 40 50
70 80 90 100 110 120
pF1KSD DLHSGPSFVESLFEEFDCDLSDLRDMPEDDGEPSKGASPELAKSPRLRNAADLPPPLPNK
.: :. : . ::. . : : . :::::..
XP_016 TANSLPA-------------------------PPQMPLPEIPQ-PWLPPDSG-PPPLPTS
60 70 80
130 140 150 160 170 180
pF1KSD PPPEDYYEEALPLGPGKSPEYISSHNGCSPSHSIVDGYYEDADSSYPATRVNGELKSSYN
:: :::::.::.:::.::::.:.
XP_016 SLPEGYYEEAVPLSPGKAPEYITSNY----------------------------------
90 100 110
190 200 210 220 230 240
pF1KSD DSDAMSSSYESYDEEEEEGKSPQPRHQWPSEEASMHLVRECRICAFLLRKKRFGQWAKQL
:::::::::::::::::.::. . ::::::::::: ::.. .::::::::::::::.: :
XP_016 DSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWTKLL
120 130 140 150 160 170
250 260 270 280 290 300
pF1KSD TVIREDQLLCYKSSKDRQPHLRLALDTCSIIYVPKDSRHKRHELRFTQGATEVLVLALQS
::.. .:::::::::.::...: :. :.: :.::::..:.:::..:: .:. ::::.::
XP_016 CVIKDTKLLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKHELKITQQGTDPLVLAVQS
180 190 200 210 220 230
310 320 330 340 350
pF1KSD REQAEEWLKVIREVSKPVGGAEGVEVPRSPVL-LCKLDLDKRLSQEKQTSDSDSVGVGDN
.::::.:::::.:. . .: : : : . : .:.:.::.:. .::...: : ..
XP_016 KEQAEQWLKVIKEAYSGCSGPVDSECPPPPSSPVHKAELEKKLSSERPSSDGEGV-VENG
240 250 260 270 280 290
360 370 380 390 400 410
pF1KSD CSTLGRRETCDHGKGKKSSLAELKGSMSRAAGRKITRIIGFSKKKTLADDLQTSSTEEEV
.: . .: : :::: .: ::..:...:.:::.::...::: .:. ::::.::.:
XP_016 ITTCNGKEQV---KRKKSSKSEAKGTVSKVTGKKITKIISLGKKKPSTDE-QTSSAEEDV
300 310 320 330 340
420 430 440 450 460 470
pF1KSD PCCGYLNVLVNQGWKERWCRLKCNTLYFHKDHMDLRTHVNAIALQGCEVAPGFGPRHPFA
: ::::::: :. :.:::::.: : : ::::. ::.::. .: :.:::: ::. .::..
XP_016 PTCGYLNVLSNSRWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKHPLT
350 360 370 380 390 400
480 490 500 510 520 530
pF1KSD FRILRNRQEVAILEASCSEDMGRWLGLLLVEMGSRVTPEALHYDYVDVETLTSIVSAGRN
::.::: ::::.:::: :::::::.:.::.: :: . ::::::::.::: .:.......
XP_016 FRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALHYDYIDVEMSASVIQTAKQ
410 420 430 440 450 460
540 550 560
pF1KSD SFL-----------YARSCQNQWPEPRV----YDDVPY--------------------EK
.: : . .: . .: ::::: :.
XP_016 TFCFMNRRVISANPYLGGTSNGYAHPSGTALHYDDVPCINGSWEPEDGFPASCSRGLGEE
470 480 490 500 510 520
570 580 590 600 610 620
pF1KSD MQDEEPERPTGAQ-VKRHASSCSEKSHRVDPQVKVKRHASSANQYKYGKNRAEEDARRYL
.. ..: :.... : .... : . ...:: . ::: .:.: ::::::::.: ::.:
XP_016 LKGKKP--PVASNGVTGKGKTLSSQPKKADPAAVVKRTGSNAAQYKYGKNRVEADAKRLQ
530 540 550 560 570 580
630 640 650 660 670 680
pF1KSD VEKEKLEKEKETIRTELIALRQEKRELKEAIRSSPGAKLKA-LEEAVATLEAQCRAKEER
...:.: :.::..:..: ::.:...:. ::. . : : .: ::: . :: .:: :: .
XP_016 TKEEELLKRKEALRNRLAQLRKERKDLRAAIEVNAGRKPQAILEEKLKQLEEECRQKEAE
590 600 610 620 630 640
690 700 710 720
pF1KSD RIDLELKLVAVKERLQQSLAGGPALGLSVSSKPKSGETA------------NKPQNSVP-
:..:::.:. ::: :...:::: .:::.. .:::: .. :.: .:
XP_016 RVSLELELTEVKESLKKALAGGVTLGLAI--EPKSGTSSPQSPVFRHRTLENSPISSCDT
650 660 670 680 690 700
730 740 750 760
pF1KSD ---EQPLPVNCVSELRKRSPSIVASNQGRVLQKAKEWEMKKT
: :.::: .. :.:
XP_016 SDTEGPVPVNSAAVLKKSQAAPGSSPCRGHVLRKAKEWELKNGT
710 720 730 740
768 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 08:57:11 2016 done: Thu Nov 3 08:57:13 2016
Total Scan time: 14.090 Total Display time: 0.220
Function used was FASTA [36.3.4 Apr, 2011]