FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDF0390, 275 aa 1>>>pF1KSDF0390 275 - 275 aa - 275 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5853+/-0.000321; mu= 10.9057+/- 0.020 mean_var=132.3491+/-25.524, 0's: 0 Z-trim(120.4): 103 B-trim: 54 in 2/55 Lambda= 0.111484 statistics sampled from 35357 (35493) to 35357 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.776), E-opt: 0.2 (0.416), width: 16 Scan time: 7.010 The best scores are: opt bits E(85289) NP_004049 (OMIM: 114212) calcyphosin isoform a [Ho ( 275) 1879 312.8 4.4e-85 NP_542157 (OMIM: 114212) calcyphosin isoform b [Ho ( 248) 1493 250.7 2e-66 XP_016875536 (OMIM: 607724) PREDICTED: calcyphosin ( 204) 365 69.2 7.1e-12 XP_016875535 (OMIM: 607724) PREDICTED: calcyphosin ( 204) 365 69.2 7.1e-12 XP_016875530 (OMIM: 607724) PREDICTED: calcyphosin ( 204) 365 69.2 7.1e-12 XP_016875533 (OMIM: 607724) PREDICTED: calcyphosin ( 204) 365 69.2 7.1e-12 XP_016875532 (OMIM: 607724) PREDICTED: calcyphosin ( 204) 365 69.2 7.1e-12 NP_001273478 (OMIM: 607724) calcyphosin-2 isoform ( 204) 365 69.2 7.1e-12 XP_016875534 (OMIM: 607724) PREDICTED: calcyphosin ( 204) 365 69.2 7.1e-12 XP_016875531 (OMIM: 607724) PREDICTED: calcyphosin ( 204) 365 69.2 7.1e-12 XP_016875529 (OMIM: 607724) PREDICTED: calcyphosin ( 268) 365 69.3 8.7e-12 XP_016875528 (OMIM: 607724) PREDICTED: calcyphosin ( 350) 365 69.4 1.1e-11 XP_016875525 (OMIM: 607724) PREDICTED: calcyphosin ( 382) 365 69.4 1.1e-11 XP_011537194 (OMIM: 607724) PREDICTED: calcyphosin ( 382) 365 69.4 1.1e-11 XP_016875526 (OMIM: 607724) PREDICTED: calcyphosin ( 382) 365 69.4 1.1e-11 XP_016875527 (OMIM: 607724) PREDICTED: calcyphosin ( 382) 365 69.4 1.1e-11 NP_001273477 (OMIM: 607724) calcyphosin-2 isoform ( 382) 365 69.4 1.1e-11 XP_016875524 (OMIM: 607724) PREDICTED: calcyphosin ( 477) 365 69.5 1.3e-11 XP_005269249 (OMIM: 607724) PREDICTED: calcyphosin ( 508) 365 69.5 1.4e-11 XP_011537190 (OMIM: 607724) PREDICTED: calcyphosin ( 509) 365 69.5 1.4e-11 XP_011537189 (OMIM: 607724) PREDICTED: calcyphosin ( 544) 365 69.6 1.5e-11 XP_016875523 (OMIM: 607724) PREDICTED: calcyphosin ( 570) 365 69.6 1.5e-11 XP_011537188 (OMIM: 607724) PREDICTED: calcyphosin ( 576) 365 69.6 1.5e-11 XP_006719712 (OMIM: 607724) PREDICTED: calcyphosin ( 582) 365 69.6 1.5e-11 XP_011537180 (OMIM: 607724) PREDICTED: calcyphosin ( 602) 365 69.6 1.6e-11 XP_011537191 (OMIM: 607724) PREDICTED: calcyphosin ( 602) 365 69.6 1.6e-11 XP_006719711 (OMIM: 607724) PREDICTED: calcyphosin ( 614) 365 69.6 1.6e-11 XP_005269251 (OMIM: 607724) PREDICTED: calcyphosin ( 293) 238 48.9 1.3e-05 NP_001273476 (OMIM: 607724) calcyphosin-2 isoform ( 475) 238 49.1 1.9e-05 NP_115995 (OMIM: 607724) calcyphosin-2 isoform 1 [ ( 557) 238 49.2 2.1e-05 >>NP_004049 (OMIM: 114212) calcyphosin isoform a [Homo s (275 aa) initn: 1879 init1: 1879 opt: 1879 Z-score: 1648.5 bits: 312.8 E(85289): 4.4e-85 Smith-Waterman score: 1879; 100.0% identity (100.0% similar) in 275 aa overlap (1-275:1-275) 10 20 30 40 50 60 pF1KSD MQCHRDLALSQALWGWQLSKQSGWAHPSLPHSPLPSTVHSCSWAPPHLQRHLPLATVSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MQCHRDLALSQALWGWQLSKQSGWAHPSLPHSPLPSTVHSCSWAPPHLQRHLPLATVSPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD TTQLTQGPAGRTLGQTQASCPEPRPSMDAVDATMEKLRAQCLSRGASGIQGLARFFRQLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TTQLTQGPAGRTLGQTQASCPEPRPSMDAVDATMEKLRAQCLSRGASGIQGLARFFRQLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RDGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEFLRALRPPMSQAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RDGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEFLRALRPPMSQAR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD EAVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSGEWTEDEVLRRFLDNFDSSEKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EAVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSGEWTEDEVLRRFLDNFDSSEKD 190 200 210 220 230 240 250 260 270 pF1KSD GQVTLAEFQDYYSGVSASMNTDEEFVAMMTSAWQL ::::::::::::::::::::::::::::::::::: NP_004 GQVTLAEFQDYYSGVSASMNTDEEFVAMMTSAWQL 250 260 270 >>NP_542157 (OMIM: 114212) calcyphosin isoform b [Homo s (248 aa) initn: 1562 init1: 1493 opt: 1493 Z-score: 1313.6 bits: 250.7 E(85289): 2e-66 Smith-Waterman score: 1631; 90.2% identity (90.2% similar) in 275 aa overlap (1-275:1-248) 10 20 30 40 50 60 pF1KSD MQCHRDLALSQALWGWQLSKQSGWAHPSLPHSPLPSTVHSCSWAPPHLQRHLPLATVSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 MQCHRDLALSQALWGWQLSKQSGWAHPSLPHSPLPSTVHSCSWAPPHLQRHLPLATVSPG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD TTQLTQGPAGRTLGQTQASCPEPRPSMDAVDATMEKLRAQCLSRGASGIQGLARFFRQLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 TTQLTQGPAGRTLGQTQASCPEPRPSMDAVDATMEKLRAQCLSRGASGIQGLARFFRQLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD RDGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEFLRALRPPMSQAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_542 RDGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEFLRALRPPMSQAR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD EAVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSGEWTEDEVLRRFLDNFDSSEKD :::::::::::::::::::::::::::::::::::: NP_542 EAVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKV------------------------ 190 200 210 250 260 270 pF1KSD GQVTLAEFQDYYSGVSASMNTDEEFVAMMTSAWQL :::::::::::::::::::::::::::::::: NP_542 ---TLAEFQDYYSGVSASMNTDEEFVAMMTSAWQL 220 230 240 >>XP_016875536 (OMIM: 607724) PREDICTED: calcyphosin-2 i (204 aa) initn: 364 init1: 261 opt: 365 Z-score: 334.2 bits: 69.2 E(85289): 7.1e-12 Smith-Waterman score: 365; 32.2% identity (65.6% similar) in 183 aa overlap (92-273:20-202) 70 80 90 100 110 120 pF1KSD TQLTQGPAGRTLGQTQASCPEPRPSMDAVDATMEKLRAQCLSRGASGIQGLARFFRQLDR : .. :. . .::. . ::...:.:::. XP_016 MEQEDDIIIQETNDRLVFKAIQDVLKEKLHKRGVRILTGLGKYFQQLDK 10 20 30 40 130 140 150 160 170 180 pF1KSD DGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEFLRALRPPMSQARE .:. :: .:.:.: . : ... . :.. . ::.: .: :: :.. :.. :. XP_016 EGNGLLDKADFKQALKVFHLEVSEKDFESAWLILNDNGNGKVDYGEFKRGIIGEMNEYRK 50 60 70 80 90 100 190 200 210 220 230 240 pF1KSD AVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSGEWTEDEVLRRFLDNFD-SSEKD . . :: ::: . .: : . ..: : .. : .: ::. ::.:. ::... . :. XP_016 SYVRKAFMKLDFNKSGSVPIINIRKCYCAKKHSQVISGHSTEEEIKSSFLETLKVACSKS 110 120 130 140 150 160 250 260 270 pF1KSD GQVTLAEFQDYYSGVSASMNTDEEFVAMMTSAWQL .:. .::.::: :.: .. ::.:: .. . : XP_016 DEVSYGEFEDYYEGLSIGIVDDEDFVNILRTPWGI 170 180 190 200 >>XP_016875535 (OMIM: 607724) PREDICTED: calcyphosin-2 i (204 aa) initn: 364 init1: 261 opt: 365 Z-score: 334.2 bits: 69.2 E(85289): 7.1e-12 Smith-Waterman score: 365; 32.2% identity (65.6% similar) in 183 aa overlap (92-273:20-202) 70 80 90 100 110 120 pF1KSD TQLTQGPAGRTLGQTQASCPEPRPSMDAVDATMEKLRAQCLSRGASGIQGLARFFRQLDR : .. :. . .::. . ::...:.:::. XP_016 MEQEDDIIIQETNDRLVFKAIQDVLKEKLHKRGVRILTGLGKYFQQLDK 10 20 30 40 130 140 150 160 170 180 pF1KSD DGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEFLRALRPPMSQARE .:. :: .:.:.: . : ... . :.. . ::.: .: :: :.. :.. :. XP_016 EGNGLLDKADFKQALKVFHLEVSEKDFESAWLILNDNGNGKVDYGEFKRGIIGEMNEYRK 50 60 70 80 90 100 190 200 210 220 230 240 pF1KSD AVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSGEWTEDEVLRRFLDNFD-SSEKD . . :: ::: . .: : . ..: : .. : .: ::. ::.:. ::... . :. XP_016 SYVRKAFMKLDFNKSGSVPIINIRKCYCAKKHSQVISGHSTEEEIKSSFLETLKVACSKS 110 120 130 140 150 160 250 260 270 pF1KSD GQVTLAEFQDYYSGVSASMNTDEEFVAMMTSAWQL .:. .::.::: :.: .. ::.:: .. . : XP_016 DEVSYGEFEDYYEGLSIGIVDDEDFVNILRTPWGI 170 180 190 200 >>XP_016875530 (OMIM: 607724) PREDICTED: calcyphosin-2 i (204 aa) initn: 364 init1: 261 opt: 365 Z-score: 334.2 bits: 69.2 E(85289): 7.1e-12 Smith-Waterman score: 365; 32.2% identity (65.6% similar) in 183 aa overlap (92-273:20-202) 70 80 90 100 110 120 pF1KSD TQLTQGPAGRTLGQTQASCPEPRPSMDAVDATMEKLRAQCLSRGASGIQGLARFFRQLDR : .. :. . .::. . ::...:.:::. XP_016 MEQEDDIIIQETNDRLVFKAIQDVLKEKLHKRGVRILTGLGKYFQQLDK 10 20 30 40 130 140 150 160 170 180 pF1KSD DGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEFLRALRPPMSQARE .:. :: .:.:.: . : ... . :.. . ::.: .: :: :.. :.. :. XP_016 EGNGLLDKADFKQALKVFHLEVSEKDFESAWLILNDNGNGKVDYGEFKRGIIGEMNEYRK 50 60 70 80 90 100 190 200 210 220 230 240 pF1KSD AVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSGEWTEDEVLRRFLDNFD-SSEKD . . :: ::: . .: : . ..: : .. : .: ::. ::.:. ::... . :. XP_016 SYVRKAFMKLDFNKSGSVPIINIRKCYCAKKHSQVISGHSTEEEIKSSFLETLKVACSKS 110 120 130 140 150 160 250 260 270 pF1KSD GQVTLAEFQDYYSGVSASMNTDEEFVAMMTSAWQL .:. .::.::: :.: .. ::.:: .. . : XP_016 DEVSYGEFEDYYEGLSIGIVDDEDFVNILRTPWGI 170 180 190 200 >>XP_016875533 (OMIM: 607724) PREDICTED: calcyphosin-2 i (204 aa) initn: 364 init1: 261 opt: 365 Z-score: 334.2 bits: 69.2 E(85289): 7.1e-12 Smith-Waterman score: 365; 32.2% identity (65.6% similar) in 183 aa overlap (92-273:20-202) 70 80 90 100 110 120 pF1KSD TQLTQGPAGRTLGQTQASCPEPRPSMDAVDATMEKLRAQCLSRGASGIQGLARFFRQLDR : .. :. . .::. . ::...:.:::. XP_016 MEQEDDIIIQETNDRLVFKAIQDVLKEKLHKRGVRILTGLGKYFQQLDK 10 20 30 40 130 140 150 160 170 180 pF1KSD DGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEFLRALRPPMSQARE .:. :: .:.:.: . : ... . :.. . ::.: .: :: :.. :.. :. XP_016 EGNGLLDKADFKQALKVFHLEVSEKDFESAWLILNDNGNGKVDYGEFKRGIIGEMNEYRK 50 60 70 80 90 100 190 200 210 220 230 240 pF1KSD AVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSGEWTEDEVLRRFLDNFD-SSEKD . . :: ::: . .: : . ..: : .. : .: ::. ::.:. ::... . :. XP_016 SYVRKAFMKLDFNKSGSVPIINIRKCYCAKKHSQVISGHSTEEEIKSSFLETLKVACSKS 110 120 130 140 150 160 250 260 270 pF1KSD GQVTLAEFQDYYSGVSASMNTDEEFVAMMTSAWQL .:. .::.::: :.: .. ::.:: .. . : XP_016 DEVSYGEFEDYYEGLSIGIVDDEDFVNILRTPWGI 170 180 190 200 >>XP_016875532 (OMIM: 607724) PREDICTED: calcyphosin-2 i (204 aa) initn: 364 init1: 261 opt: 365 Z-score: 334.2 bits: 69.2 E(85289): 7.1e-12 Smith-Waterman score: 365; 32.2% identity (65.6% similar) in 183 aa overlap (92-273:20-202) 70 80 90 100 110 120 pF1KSD TQLTQGPAGRTLGQTQASCPEPRPSMDAVDATMEKLRAQCLSRGASGIQGLARFFRQLDR : .. :. . .::. . ::...:.:::. XP_016 MEQEDDIIIQETNDRLVFKAIQDVLKEKLHKRGVRILTGLGKYFQQLDK 10 20 30 40 130 140 150 160 170 180 pF1KSD DGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEFLRALRPPMSQARE .:. :: .:.:.: . : ... . :.. . ::.: .: :: :.. :.. :. XP_016 EGNGLLDKADFKQALKVFHLEVSEKDFESAWLILNDNGNGKVDYGEFKRGIIGEMNEYRK 50 60 70 80 90 100 190 200 210 220 230 240 pF1KSD AVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSGEWTEDEVLRRFLDNFD-SSEKD . . :: ::: . .: : . ..: : .. : .: ::. ::.:. ::... . :. XP_016 SYVRKAFMKLDFNKSGSVPIINIRKCYCAKKHSQVISGHSTEEEIKSSFLETLKVACSKS 110 120 130 140 150 160 250 260 270 pF1KSD GQVTLAEFQDYYSGVSASMNTDEEFVAMMTSAWQL .:. .::.::: :.: .. ::.:: .. . : XP_016 DEVSYGEFEDYYEGLSIGIVDDEDFVNILRTPWGI 170 180 190 200 >>NP_001273478 (OMIM: 607724) calcyphosin-2 isoform 4 [H (204 aa) initn: 364 init1: 261 opt: 365 Z-score: 334.2 bits: 69.2 E(85289): 7.1e-12 Smith-Waterman score: 365; 32.2% identity (65.6% similar) in 183 aa overlap (92-273:20-202) 70 80 90 100 110 120 pF1KSD TQLTQGPAGRTLGQTQASCPEPRPSMDAVDATMEKLRAQCLSRGASGIQGLARFFRQLDR : .. :. . .::. . ::...:.:::. NP_001 MEQEDDIIIQETNDRLVFKAIQDVLKEKLHKRGVRILTGLGKYFQQLDK 10 20 30 40 130 140 150 160 170 180 pF1KSD DGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEFLRALRPPMSQARE .:. :: .:.:.: . : ... . :.. . ::.: .: :: :.. :.. :. NP_001 EGNGLLDKADFKQALKVFHLEVSEKDFESAWLILNDNGNGKVDYGEFKRGIIGEMNEYRK 50 60 70 80 90 100 190 200 210 220 230 240 pF1KSD AVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSGEWTEDEVLRRFLDNFD-SSEKD . . :: ::: . .: : . ..: : .. : .: ::. ::.:. ::... . :. NP_001 SYVRKAFMKLDFNKSGSVPIINIRKCYCAKKHSQVISGHSTEEEIKSSFLETLKVACSKS 110 120 130 140 150 160 250 260 270 pF1KSD GQVTLAEFQDYYSGVSASMNTDEEFVAMMTSAWQL .:. .::.::: :.: .. ::.:: .. . : NP_001 DEVSYGEFEDYYEGLSIGIVDDEDFVNILRTPWGI 170 180 190 200 >>XP_016875534 (OMIM: 607724) PREDICTED: calcyphosin-2 i (204 aa) initn: 364 init1: 261 opt: 365 Z-score: 334.2 bits: 69.2 E(85289): 7.1e-12 Smith-Waterman score: 365; 32.2% identity (65.6% similar) in 183 aa overlap (92-273:20-202) 70 80 90 100 110 120 pF1KSD TQLTQGPAGRTLGQTQASCPEPRPSMDAVDATMEKLRAQCLSRGASGIQGLARFFRQLDR : .. :. . .::. . ::...:.:::. XP_016 MEQEDDIIIQETNDRLVFKAIQDVLKEKLHKRGVRILTGLGKYFQQLDK 10 20 30 40 130 140 150 160 170 180 pF1KSD DGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEFLRALRPPMSQARE .:. :: .:.:.: . : ... . :.. . ::.: .: :: :.. :.. :. XP_016 EGNGLLDKADFKQALKVFHLEVSEKDFESAWLILNDNGNGKVDYGEFKRGIIGEMNEYRK 50 60 70 80 90 100 190 200 210 220 230 240 pF1KSD AVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSGEWTEDEVLRRFLDNFD-SSEKD . . :: ::: . .: : . ..: : .. : .: ::. ::.:. ::... . :. XP_016 SYVRKAFMKLDFNKSGSVPIINIRKCYCAKKHSQVISGHSTEEEIKSSFLETLKVACSKS 110 120 130 140 150 160 250 260 270 pF1KSD GQVTLAEFQDYYSGVSASMNTDEEFVAMMTSAWQL .:. .::.::: :.: .. ::.:: .. . : XP_016 DEVSYGEFEDYYEGLSIGIVDDEDFVNILRTPWGI 170 180 190 200 >>XP_016875531 (OMIM: 607724) PREDICTED: calcyphosin-2 i (204 aa) initn: 364 init1: 261 opt: 365 Z-score: 334.2 bits: 69.2 E(85289): 7.1e-12 Smith-Waterman score: 365; 32.2% identity (65.6% similar) in 183 aa overlap (92-273:20-202) 70 80 90 100 110 120 pF1KSD TQLTQGPAGRTLGQTQASCPEPRPSMDAVDATMEKLRAQCLSRGASGIQGLARFFRQLDR : .. :. . .::. . ::...:.:::. XP_016 MEQEDDIIIQETNDRLVFKAIQDVLKEKLHKRGVRILTGLGKYFQQLDK 10 20 30 40 130 140 150 160 170 180 pF1KSD DGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEFLRALRPPMSQARE .:. :: .:.:.: . : ... . :.. . ::.: .: :: :.. :.. :. XP_016 EGNGLLDKADFKQALKVFHLEVSEKDFESAWLILNDNGNGKVDYGEFKRGIIGEMNEYRK 50 60 70 80 90 100 190 200 210 220 230 240 pF1KSD AVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSGEWTEDEVLRRFLDNFD-SSEKD . . :: ::: . .: : . ..: : .. : .: ::. ::.:. ::... . :. XP_016 SYVRKAFMKLDFNKSGSVPIINIRKCYCAKKHSQVISGHSTEEEIKSSFLETLKVACSKS 110 120 130 140 150 160 250 260 270 pF1KSD GQVTLAEFQDYYSGVSASMNTDEEFVAMMTSAWQL .:. .::.::: :.: .. ::.:: .. . : XP_016 DEVSYGEFEDYYEGLSIGIVDDEDFVNILRTPWGI 170 180 190 200 275 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 09:01:11 2016 done: Thu Nov 3 09:01:12 2016 Total Scan time: 7.010 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]