FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDF0400, 726 aa
1>>>pF1KSDF0400 726 - 726 aa - 726 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0085+/-0.000359; mu= 8.6703+/- 0.022
mean_var=190.7734+/-38.892, 0's: 0 Z-trim(120.0): 32 B-trim: 87 in 1/53
Lambda= 0.092857
statistics sampled from 34654 (34686) to 34654 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.73), E-opt: 0.2 (0.407), width: 16
Scan time: 13.810
The best scores are: opt bits E(85289)
NP_689681 (OMIM: 226400,605829) transmembrane chan ( 726) 4920 672.0 2.3e-192
XP_011522706 (OMIM: 226400,605829) PREDICTED: tran ( 730) 4902 669.6 1.2e-191
XP_011522705 (OMIM: 226400,605829) PREDICTED: tran ( 734) 4894 668.5 2.6e-191
XP_011522704 (OMIM: 226400,605829) PREDICTED: tran ( 738) 4876 666.1 1.4e-190
XP_016879727 (OMIM: 226400,605829) PREDICTED: tran ( 737) 3704 509.1 2.5e-143
XP_016879728 (OMIM: 226400,605829) PREDICTED: tran ( 714) 3438 473.5 1.3e-132
XP_016879729 (OMIM: 226400,605829) PREDICTED: tran ( 706) 3414 470.3 1.2e-131
XP_016879731 (OMIM: 226400,605829) PREDICTED: tran ( 451) 2981 412.1 2.5e-114
XP_016879732 (OMIM: 226400,605829) PREDICTED: tran ( 435) 2712 376.0 1.7e-103
XP_016879730 (OMIM: 226400,605829) PREDICTED: tran ( 491) 2671 370.6 8.4e-102
XP_011522713 (OMIM: 226400,605829) PREDICTED: tran ( 393) 2487 345.9 1.9e-94
XP_016879733 (OMIM: 226400,605829) PREDICTED: tran ( 426) 2198 307.2 9e-83
XP_011522712 (OMIM: 226400,605829) PREDICTED: tran ( 412) 2180 304.7 4.7e-82
XP_011522711 (OMIM: 226400,605829) PREDICTED: tran ( 430) 2180 304.8 4.8e-82
XP_011522708 (OMIM: 226400,605829) PREDICTED: tran ( 699) 2180 304.9 6.9e-82
NP_542789 (OMIM: 606707) transmembrane channel-lik ( 906) 384 64.4 2.3e-09
XP_005260717 (OMIM: 606707) PREDICTED: transmembra ( 931) 384 64.4 2.3e-09
XP_011522559 (OMIM: 226400,605828) PREDICTED: tran ( 535) 370 62.4 5.6e-09
XP_016879598 (OMIM: 226400,605828) PREDICTED: tran ( 578) 370 62.4 5.9e-09
XP_011522558 (OMIM: 226400,605828) PREDICTED: tran ( 763) 370 62.5 7.3e-09
XP_005257052 (OMIM: 226400,605828) PREDICTED: tran ( 805) 370 62.5 7.6e-09
NP_001120670 (OMIM: 226400,605828) transmembrane c ( 805) 370 62.5 7.6e-09
NP_009198 (OMIM: 226400,605828) transmembrane chan ( 805) 370 62.5 7.6e-09
NP_001308114 (OMIM: 226400,605828) transmembrane c ( 805) 370 62.5 7.6e-09
XP_011522557 (OMIM: 226400,605828) PREDICTED: tran ( 805) 370 62.5 7.6e-09
NP_619636 (OMIM: 600974,606705,606706) transmembra ( 760) 346 59.3 6.7e-08
XP_016869745 (OMIM: 600974,606705,606706) PREDICTE ( 761) 346 59.3 6.7e-08
XP_016879597 (OMIM: 226400,605828) PREDICTED: tran ( 745) 295 52.4 7.6e-06
XP_016879596 (OMIM: 226400,605828) PREDICTED: tran ( 745) 295 52.4 7.6e-06
>>NP_689681 (OMIM: 226400,605829) transmembrane channel- (726 aa)
initn: 4920 init1: 4920 opt: 4920 Z-score: 3574.6 bits: 672.0 E(85289): 2.3e-192
Smith-Waterman score: 4920; 99.7% identity (99.7% similar) in 726 aa overlap (1-726:1-726)
10 20 30 40 50 60
pF1KSD MLLPWSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT
:::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD RVNVLIGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQ
::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 RVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD NSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 NSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD GQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 GQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD GLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 GLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KSD FPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 FPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KSD PKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASARRFRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 PKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASARRFRF
670 680 690 700 710 720
pF1KSD PSGAEL
::::::
NP_689 PSGAEL
>>XP_011522706 (OMIM: 226400,605829) PREDICTED: transmem (730 aa)
initn: 3080 init1: 3080 opt: 4902 Z-score: 3561.6 bits: 669.6 E(85289): 1.2e-191
Smith-Waterman score: 4902; 99.2% identity (99.2% similar) in 730 aa overlap (1-726:1-730)
10 20 30 40 50 60
pF1KSD MLLPWSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT
:::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA
190 200 210 220 230 240
250 260 270 280 290
pF1KSD PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKV----ELEEGRRFQLMQQQTRAQTACRL
::::::::::::::::::::::::::::::::: :::::::::::::::::::::::
XP_011 PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVCARVELEEGRRFQLMQQQTRAQTACRL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD LSYLRVNVLIGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSYLRVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD DIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQL
490 500 510 520 530 540
540 550 560 570 580 590
pF1KSD VLLLGLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLLLGLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGS
550 560 570 580 590 600
600 610 620 630 640 650
pF1KSD HAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPS
610 620 630 640 650 660
660 670 680 690 700 710
pF1KSD DSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASAR
670 680 690 700 710 720
720
pF1KSD RFRFPSGAEL
::::::::::
XP_011 RFRFPSGAEL
730
>>XP_011522705 (OMIM: 226400,605829) PREDICTED: transmem (734 aa)
initn: 3734 init1: 3688 opt: 4894 Z-score: 3555.8 bits: 668.5 E(85289): 2.6e-191
Smith-Waterman score: 4894; 98.6% identity (98.6% similar) in 734 aa overlap (1-726:1-734)
10 20 30 40 50 60
pF1KSD MLLPWSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT
:::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD RVNVLIGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQ
::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD LENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD NSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD GQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLL
490 500 510 520 530 540
550 560 570 580 590
pF1KSD GLLLAAVPLGYVVSS--------IHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALH
::::::::::::::: :::::::::::::::::::::::::::::::::::::
XP_011 GLLLAAVPLGYVVSSPTWPSLASIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALH
550 560 570 580 590 600
600 610 620 630 640 650
pF1KSD YLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPE
610 620 630 640 650 660
660 670 680 690 700 710
pF1KSD PGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAP
670 680 690 700 710 720
720
pF1KSD ASARRFRFPSGAEL
::::::::::::::
XP_011 ASARRFRFPSGAEL
730
>>XP_011522704 (OMIM: 226400,605829) PREDICTED: transmem (738 aa)
initn: 3073 init1: 1848 opt: 4876 Z-score: 3542.7 bits: 666.1 E(85289): 1.4e-190
Smith-Waterman score: 4876; 98.1% identity (98.1% similar) in 738 aa overlap (1-726:1-738)
10 20 30 40 50 60
pF1KSD MLLPWSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT
:::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA
190 200 210 220 230 240
250 260 270 280 290
pF1KSD PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKV----ELEEGRRFQLMQQQTRAQTACRL
::::::::::::::::::::::::::::::::: :::::::::::::::::::::::
XP_011 PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVCARVELEEGRRFQLMQQQTRAQTACRL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD LSYLRVNVLIGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSYLRVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD DIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQL
490 500 510 520 530 540
540 550 560 570 580
pF1KSD VLLLGLLLAAVPLGYVVSS--------IHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQ
::::::::::::::::::: :::::::::::::::::::::::::::::::::
XP_011 VLLLGLLLAAVPLGYVVSSPTWPSLASIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQ
550 560 570 580 590 600
590 600 610 620 630 640
pF1KSD RALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSR
610 620 630 640 650 660
650 660 670 680 690 700
pF1KSD LLPEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLPEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQ
670 680 690 700 710 720
710 720
pF1KSD HGAPASARRFRFPSGAEL
::::::::::::::::::
XP_011 HGAPASARRFRFPSGAEL
730
>>XP_016879727 (OMIM: 226400,605829) PREDICTED: transmem (737 aa)
initn: 3052 init1: 1848 opt: 3704 Z-score: 2694.2 bits: 509.1 E(85289): 2.5e-143
Smith-Waterman score: 4857; 98.0% identity (98.0% similar) in 738 aa overlap (1-726:1-737)
10 20 30 40 50 60
pF1KSD MLLPWSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT
:::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA
190 200 210 220 230 240
250 260 270 280 290
pF1KSD PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKV----ELEEGRRFQLMQQQTRAQTACRL
::::::::::::::::::::::::::::::::: :::::::::::::::::::::::
XP_016 PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVCARVELEEGRRFQLMQQQTRAQTACRL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD LSYLRVNVLIGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSYLRVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD DIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQL
490 500 510 520 530 540
540 550 560 570 580
pF1KSD VLLLGLLLAAVPLGYVVSS--------IHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQ
::::::::::::::::::: :::::::::::::::::::::::::::::::::
XP_016 VLLLGLLLAAVPLGYVVSSPTWPSLASIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQ
550 560 570 580 590 600
590 600 610 620 630 640
pF1KSD RALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSR
:::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
XP_016 RALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVW-VQEKWHLVEDLSR
610 620 630 640 650
650 660 670 680 690 700
pF1KSD LLPEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLPEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQ
660 670 680 690 700 710
710 720
pF1KSD HGAPASARRFRFPSGAEL
::::::::::::::::::
XP_016 HGAPASARRFRFPSGAEL
720 730
>>XP_016879728 (OMIM: 226400,605829) PREDICTED: transmem (714 aa)
initn: 3073 init1: 1848 opt: 3438 Z-score: 2501.8 bits: 473.5 E(85289): 1.3e-132
Smith-Waterman score: 4667; 94.9% identity (94.9% similar) in 738 aa overlap (1-726:1-714)
10 20 30 40 50 60
pF1KSD MLLPWSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT
:::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA
190 200 210 220 230 240
250 260 270 280 290
pF1KSD PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKV----ELEEGRRFQLMQQQTRAQTACRL
::::::::::::::::::::::::::::::::: :::::::::::::::::::::::
XP_016 PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVCARVELEEGRRFQLMQQQTRAQTACRL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD LSYLRVNVLIGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSYLRVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD DIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQL
::::::::::::::::::::::::::::::::::: :
XP_016 DIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKK------------------------L
490 500 510
540 550 560 570 580
pF1KSD VLLLGLLLAAVPLGYVVSS--------IHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQ
::::::::::::::::::: :::::::::::::::::::::::::::::::::
XP_016 VLLLGLLLAAVPLGYVVSSPTWPSLASIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQ
520 530 540 550 560 570
590 600 610 620 630 640
pF1KSD RALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSR
580 590 600 610 620 630
650 660 670 680 690 700
pF1KSD LLPEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLPEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQ
640 650 660 670 680 690
710 720
pF1KSD HGAPASARRFRFPSGAEL
::::::::::::::::::
XP_016 HGAPASARRFRFPSGAEL
700 710
>>XP_016879729 (OMIM: 226400,605829) PREDICTED: transmem (706 aa)
initn: 3182 init1: 1848 opt: 3414 Z-score: 2484.5 bits: 470.3 E(85289): 1.2e-131
Smith-Waterman score: 4693; 95.9% identity (95.9% similar) in 730 aa overlap (1-726:1-706)
10 20 30 40 50 60
pF1KSD MLLPWSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT
:::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA
190 200 210 220 230 240
250 260 270 280 290
pF1KSD PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKV----ELEEGRRFQLMQQQTRAQTACRL
::::::::::::::::::::::::::::::::: :::::::::::::::::::::::
XP_016 PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVCARVELEEGRRFQLMQQQTRAQTACRL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD LSYLRVNVLIGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSYLRVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL
430 440 450 460 470 480
480 490 500 510 520 530
pF1KSD DIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQL
::::::::::::::::::::::::::::::::::: :
XP_016 DIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKK------------------------L
490 500 510
540 550 560 570 580 590
pF1KSD VLLLGLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLLLGLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGS
520 530 540 550 560 570
600 610 620 630 640 650
pF1KSD HAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPS
580 590 600 610 620 630
660 670 680 690 700 710
pF1KSD DSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASAR
640 650 660 670 680 690
720
pF1KSD RFRFPSGAEL
::::::::::
XP_016 RFRFPSGAEL
700
>>XP_016879731 (OMIM: 226400,605829) PREDICTED: transmem (451 aa)
initn: 1821 init1: 1775 opt: 2981 Z-score: 2173.6 bits: 412.1 E(85289): 2.5e-114
Smith-Waterman score: 2981; 98.0% identity (98.0% similar) in 451 aa overlap (284-726:1-451)
260 270 280 290 300 310
pF1KSD IRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLIGLLVVGA
:::::::::::::::::::::: :::::::
XP_016 MQQQTRAQTACRLLSYLRVNVLNGLLVVGA
10 20 30
320 330 340 350 360 370
pF1KSD ISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLT
40 50 60 70 80 90
380 390 400 410 420 430
pF1KSD LIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWENSVGEELYKLSIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWENSVGEELYKLSIF
100 110 120 130 140 150
440 450 460 470 480 490
pF1KSD NFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVTWMGLFYCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVTWMGLFYCP
160 170 180 190 200 210
500 510 520 530 540 550
pF1KSD LLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLLGLLLAAVPLGYVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLLGLLLAAVPLGYVV
220 230 240 250 260 270
560 570 580 590 600
pF1KSD SS--------IHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLI
:: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSPTWPSLASIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLI
280 290 300 310 320 330
610 620 630 640 650 660
pF1KSD MLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPGPKYPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPGPKYPA
340 350 360 370 380 390
670 680 690 700 710 720
pF1KSD SQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASARRFRFPSGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASARRFRFPSGAE
400 410 420 430 440 450
pF1KSD L
:
XP_016 L
>>XP_016879732 (OMIM: 226400,605829) PREDICTED: transmem (435 aa)
initn: 2712 init1: 2712 opt: 2712 Z-score: 1979.0 bits: 376.0 E(85289): 1.7e-103
Smith-Waterman score: 2712; 99.8% identity (99.8% similar) in 411 aa overlap (224-634:1-411)
200 210 220 230 240 250
pF1KSD ESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFC
::::::::::::::::::::::::::::::
XP_016 MVKGLPQKTLLGQGYQAPLSAKVFSSWDFC
10 20 30
260 270 280 290 300 310
pF1KSD IRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLIGLLVVGA
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
XP_016 IRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLVVGA
40 50 60 70 80 90
320 330 340 350 360 370
pF1KSD ISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLT
100 110 120 130 140 150
380 390 400 410 420 430
pF1KSD LIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWENSVGEELYKLSIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWENSVGEELYKLSIF
160 170 180 190 200 210
440 450 460 470 480 490
pF1KSD NFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVTWMGLFYCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVTWMGLFYCP
220 230 240 250 260 270
500 510 520 530 540 550
pF1KSD LLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLLGLLLAAVPLGYVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLLGLLLAAVPLGYVV
280 290 300 310 320 330
560 570 580 590 600 610
pF1KSD SSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLIMLSLVLTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLIMLSLVLTV
340 350 360 370 380 390
620 630 640 650 660 670
pF1KSD CVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPGPKYPASQASRPQS
:::::::::::::::::::::
XP_016 CVSQTQANARAIHRLRKQLVWVSVLGAGEGTAASVETLPYVWPRA
400 410 420 430
>>XP_016879730 (OMIM: 226400,605829) PREDICTED: transmem (491 aa)
initn: 1878 init1: 1848 opt: 2671 Z-score: 1948.6 bits: 370.6 E(85289): 8.4e-102
Smith-Waterman score: 2671; 98.5% identity (98.5% similar) in 409 aa overlap (1-405:1-409)
10 20 30 40 50 60
pF1KSD MLLPWSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT
:::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA
190 200 210 220 230 240
250 260 270 280 290
pF1KSD PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKV----ELEEGRRFQLMQQQTRAQTACRL
::::::::::::::::::::::::::::::::: :::::::::::::::::::::::
XP_016 PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVCARVELEEGRRFQLMQQQTRAQTACRL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KSD LSYLRVNVLIGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSYLRVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT
310 320 330 340 350 360
360 370 380 390 400 410
pF1KSD FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSLLGELRGGGAV
370 380 390 400 410 420
420 430 440 450 460 470
pF1KSD QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL
XP_016 QAEYLQLPPHRGLRLPGHPASEAAGGPVLRPVLGLAGTGGVPGPQECAGHRGGADGHLDG
430 440 450 460 470 480
726 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 09:01:43 2016 done: Thu Nov 3 09:01:45 2016
Total Scan time: 13.810 Total Display time: 0.210
Function used was FASTA [36.3.4 Apr, 2011]