FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KSDF0400, 726 aa 1>>>pF1KSDF0400 726 - 726 aa - 726 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.0085+/-0.000359; mu= 8.6703+/- 0.022 mean_var=190.7734+/-38.892, 0's: 0 Z-trim(120.0): 32 B-trim: 87 in 1/53 Lambda= 0.092857 statistics sampled from 34654 (34686) to 34654 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.73), E-opt: 0.2 (0.407), width: 16 Scan time: 13.810 The best scores are: opt bits E(85289) NP_689681 (OMIM: 226400,605829) transmembrane chan ( 726) 4920 672.0 2.3e-192 XP_011522706 (OMIM: 226400,605829) PREDICTED: tran ( 730) 4902 669.6 1.2e-191 XP_011522705 (OMIM: 226400,605829) PREDICTED: tran ( 734) 4894 668.5 2.6e-191 XP_011522704 (OMIM: 226400,605829) PREDICTED: tran ( 738) 4876 666.1 1.4e-190 XP_016879727 (OMIM: 226400,605829) PREDICTED: tran ( 737) 3704 509.1 2.5e-143 XP_016879728 (OMIM: 226400,605829) PREDICTED: tran ( 714) 3438 473.5 1.3e-132 XP_016879729 (OMIM: 226400,605829) PREDICTED: tran ( 706) 3414 470.3 1.2e-131 XP_016879731 (OMIM: 226400,605829) PREDICTED: tran ( 451) 2981 412.1 2.5e-114 XP_016879732 (OMIM: 226400,605829) PREDICTED: tran ( 435) 2712 376.0 1.7e-103 XP_016879730 (OMIM: 226400,605829) PREDICTED: tran ( 491) 2671 370.6 8.4e-102 XP_011522713 (OMIM: 226400,605829) PREDICTED: tran ( 393) 2487 345.9 1.9e-94 XP_016879733 (OMIM: 226400,605829) PREDICTED: tran ( 426) 2198 307.2 9e-83 XP_011522712 (OMIM: 226400,605829) PREDICTED: tran ( 412) 2180 304.7 4.7e-82 XP_011522711 (OMIM: 226400,605829) PREDICTED: tran ( 430) 2180 304.8 4.8e-82 XP_011522708 (OMIM: 226400,605829) PREDICTED: tran ( 699) 2180 304.9 6.9e-82 NP_542789 (OMIM: 606707) transmembrane channel-lik ( 906) 384 64.4 2.3e-09 XP_005260717 (OMIM: 606707) PREDICTED: transmembra ( 931) 384 64.4 2.3e-09 XP_011522559 (OMIM: 226400,605828) PREDICTED: tran ( 535) 370 62.4 5.6e-09 XP_016879598 (OMIM: 226400,605828) PREDICTED: tran ( 578) 370 62.4 5.9e-09 XP_011522558 (OMIM: 226400,605828) PREDICTED: tran ( 763) 370 62.5 7.3e-09 XP_005257052 (OMIM: 226400,605828) PREDICTED: tran ( 805) 370 62.5 7.6e-09 NP_001120670 (OMIM: 226400,605828) transmembrane c ( 805) 370 62.5 7.6e-09 NP_009198 (OMIM: 226400,605828) transmembrane chan ( 805) 370 62.5 7.6e-09 NP_001308114 (OMIM: 226400,605828) transmembrane c ( 805) 370 62.5 7.6e-09 XP_011522557 (OMIM: 226400,605828) PREDICTED: tran ( 805) 370 62.5 7.6e-09 NP_619636 (OMIM: 600974,606705,606706) transmembra ( 760) 346 59.3 6.7e-08 XP_016869745 (OMIM: 600974,606705,606706) PREDICTE ( 761) 346 59.3 6.7e-08 XP_016879597 (OMIM: 226400,605828) PREDICTED: tran ( 745) 295 52.4 7.6e-06 XP_016879596 (OMIM: 226400,605828) PREDICTED: tran ( 745) 295 52.4 7.6e-06 >>NP_689681 (OMIM: 226400,605829) transmembrane channel- (726 aa) initn: 4920 init1: 4920 opt: 4920 Z-score: 3574.6 bits: 672.0 E(85289): 2.3e-192 Smith-Waterman score: 4920; 99.7% identity (99.7% similar) in 726 aa overlap (1-726:1-726) 10 20 30 40 50 60 pF1KSD MLLPWSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT :::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RVNVLIGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQ ::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 RVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 LENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 NSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 GQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KSD GLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 GLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KSD FPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 FPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KSD PKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASARRFRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 PKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASARRFRF 670 680 690 700 710 720 pF1KSD PSGAEL :::::: NP_689 PSGAEL >>XP_011522706 (OMIM: 226400,605829) PREDICTED: transmem (730 aa) initn: 3080 init1: 3080 opt: 4902 Z-score: 3561.6 bits: 669.6 E(85289): 1.2e-191 Smith-Waterman score: 4902; 99.2% identity (99.2% similar) in 730 aa overlap (1-726:1-730) 10 20 30 40 50 60 pF1KSD MLLPWSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT :::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA 190 200 210 220 230 240 250 260 270 280 290 pF1KSD PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKV----ELEEGRRFQLMQQQTRAQTACRL ::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_011 PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVCARVELEEGRRFQLMQQQTRAQTACRL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD LSYLRVNVLIGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT ::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSYLRVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD DIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQL 490 500 510 520 530 540 540 550 560 570 580 590 pF1KSD VLLLGLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLLLGLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGS 550 560 570 580 590 600 600 610 620 630 640 650 pF1KSD HAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPS 610 620 630 640 650 660 660 670 680 690 700 710 pF1KSD DSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASAR 670 680 690 700 710 720 720 pF1KSD RFRFPSGAEL :::::::::: XP_011 RFRFPSGAEL 730 >>XP_011522705 (OMIM: 226400,605829) PREDICTED: transmem (734 aa) initn: 3734 init1: 3688 opt: 4894 Z-score: 3555.8 bits: 668.5 E(85289): 2.6e-191 Smith-Waterman score: 4894; 98.6% identity (98.6% similar) in 734 aa overlap (1-726:1-734) 10 20 30 40 50 60 pF1KSD MLLPWSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT :::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KSD PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KSD RVNVLIGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQ ::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KSD LENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KSD NSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KSD GQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLL 490 500 510 520 530 540 550 560 570 580 590 pF1KSD GLLLAAVPLGYVVSS--------IHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALH ::::::::::::::: ::::::::::::::::::::::::::::::::::::: XP_011 GLLLAAVPLGYVVSSPTWPSLASIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALH 550 560 570 580 590 600 600 610 620 630 640 650 pF1KSD YLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPE 610 620 630 640 650 660 660 670 680 690 700 710 pF1KSD PGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAP 670 680 690 700 710 720 720 pF1KSD ASARRFRFPSGAEL :::::::::::::: XP_011 ASARRFRFPSGAEL 730 >>XP_011522704 (OMIM: 226400,605829) PREDICTED: transmem (738 aa) initn: 3073 init1: 1848 opt: 4876 Z-score: 3542.7 bits: 666.1 E(85289): 1.4e-190 Smith-Waterman score: 4876; 98.1% identity (98.1% similar) in 738 aa overlap (1-726:1-738) 10 20 30 40 50 60 pF1KSD MLLPWSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT :::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA 190 200 210 220 230 240 250 260 270 280 290 pF1KSD PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKV----ELEEGRRFQLMQQQTRAQTACRL ::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_011 PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVCARVELEEGRRFQLMQQQTRAQTACRL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD LSYLRVNVLIGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT ::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSYLRVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD DIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQL 490 500 510 520 530 540 540 550 560 570 580 pF1KSD VLLLGLLLAAVPLGYVVSS--------IHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQ ::::::::::::::::::: ::::::::::::::::::::::::::::::::: XP_011 VLLLGLLLAAVPLGYVVSSPTWPSLASIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQ 550 560 570 580 590 600 590 600 610 620 630 640 pF1KSD RALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSR 610 620 630 640 650 660 650 660 670 680 690 700 pF1KSD LLPEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLPEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQ 670 680 690 700 710 720 710 720 pF1KSD HGAPASARRFRFPSGAEL :::::::::::::::::: XP_011 HGAPASARRFRFPSGAEL 730 >>XP_016879727 (OMIM: 226400,605829) PREDICTED: transmem (737 aa) initn: 3052 init1: 1848 opt: 3704 Z-score: 2694.2 bits: 509.1 E(85289): 2.5e-143 Smith-Waterman score: 4857; 98.0% identity (98.0% similar) in 738 aa overlap (1-726:1-737) 10 20 30 40 50 60 pF1KSD MLLPWSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT :::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA 190 200 210 220 230 240 250 260 270 280 290 pF1KSD PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKV----ELEEGRRFQLMQQQTRAQTACRL ::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_016 PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVCARVELEEGRRFQLMQQQTRAQTACRL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD LSYLRVNVLIGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT ::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSYLRVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD DIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQL 490 500 510 520 530 540 540 550 560 570 580 pF1KSD VLLLGLLLAAVPLGYVVSS--------IHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQ ::::::::::::::::::: ::::::::::::::::::::::::::::::::: XP_016 VLLLGLLLAAVPLGYVVSSPTWPSLASIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQ 550 560 570 580 590 600 590 600 610 620 630 640 pF1KSD RALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSR :::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::: XP_016 RALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVW-VQEKWHLVEDLSR 610 620 630 640 650 650 660 670 680 690 700 pF1KSD LLPEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLPEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQ 660 670 680 690 700 710 710 720 pF1KSD HGAPASARRFRFPSGAEL :::::::::::::::::: XP_016 HGAPASARRFRFPSGAEL 720 730 >>XP_016879728 (OMIM: 226400,605829) PREDICTED: transmem (714 aa) initn: 3073 init1: 1848 opt: 3438 Z-score: 2501.8 bits: 473.5 E(85289): 1.3e-132 Smith-Waterman score: 4667; 94.9% identity (94.9% similar) in 738 aa overlap (1-726:1-714) 10 20 30 40 50 60 pF1KSD MLLPWSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT :::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA 190 200 210 220 230 240 250 260 270 280 290 pF1KSD PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKV----ELEEGRRFQLMQQQTRAQTACRL ::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_016 PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVCARVELEEGRRFQLMQQQTRAQTACRL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD LSYLRVNVLIGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT ::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSYLRVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD DIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQL ::::::::::::::::::::::::::::::::::: : XP_016 DIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKK------------------------L 490 500 510 540 550 560 570 580 pF1KSD VLLLGLLLAAVPLGYVVSS--------IHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQ ::::::::::::::::::: ::::::::::::::::::::::::::::::::: XP_016 VLLLGLLLAAVPLGYVVSSPTWPSLASIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQ 520 530 540 550 560 570 590 600 610 620 630 640 pF1KSD RALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RALHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSR 580 590 600 610 620 630 650 660 670 680 690 700 pF1KSD LLPEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLPEPGPSDSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQ 640 650 660 670 680 690 710 720 pF1KSD HGAPASARRFRFPSGAEL :::::::::::::::::: XP_016 HGAPASARRFRFPSGAEL 700 710 >>XP_016879729 (OMIM: 226400,605829) PREDICTED: transmem (706 aa) initn: 3182 init1: 1848 opt: 3414 Z-score: 2484.5 bits: 470.3 E(85289): 1.2e-131 Smith-Waterman score: 4693; 95.9% identity (95.9% similar) in 730 aa overlap (1-726:1-706) 10 20 30 40 50 60 pF1KSD MLLPWSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT :::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA 190 200 210 220 230 240 250 260 270 280 290 pF1KSD PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKV----ELEEGRRFQLMQQQTRAQTACRL ::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_016 PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVCARVELEEGRRFQLMQQQTRAQTACRL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD LSYLRVNVLIGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT ::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSYLRVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL 430 440 450 460 470 480 480 490 500 510 520 530 pF1KSD DIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQL ::::::::::::::::::::::::::::::::::: : XP_016 DIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKK------------------------L 490 500 510 540 550 560 570 580 590 pF1KSD VLLLGLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLLLGLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGS 520 530 540 550 560 570 600 610 620 630 640 650 pF1KSD HAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPS 580 590 600 610 620 630 660 670 680 690 700 710 pF1KSD DSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSPGPKYPASQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASAR 640 650 660 670 680 690 720 pF1KSD RFRFPSGAEL :::::::::: XP_016 RFRFPSGAEL 700 >>XP_016879731 (OMIM: 226400,605829) PREDICTED: transmem (451 aa) initn: 1821 init1: 1775 opt: 2981 Z-score: 2173.6 bits: 412.1 E(85289): 2.5e-114 Smith-Waterman score: 2981; 98.0% identity (98.0% similar) in 451 aa overlap (284-726:1-451) 260 270 280 290 300 310 pF1KSD IRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLIGLLVVGA :::::::::::::::::::::: ::::::: XP_016 MQQQTRAQTACRLLSYLRVNVLNGLLVVGA 10 20 30 320 330 340 350 360 370 pF1KSD ISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLT 40 50 60 70 80 90 380 390 400 410 420 430 pF1KSD LIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWENSVGEELYKLSIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWENSVGEELYKLSIF 100 110 120 130 140 150 440 450 460 470 480 490 pF1KSD NFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVTWMGLFYCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVTWMGLFYCP 160 170 180 190 200 210 500 510 520 530 540 550 pF1KSD LLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLLGLLLAAVPLGYVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLLGLLLAAVPLGYVV 220 230 240 250 260 270 560 570 580 590 600 pF1KSD SS--------IHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLI :: :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSPTWPSLASIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLI 280 290 300 310 320 330 610 620 630 640 650 660 pF1KSD MLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPGPKYPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLSLVLTVCVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPGPKYPA 340 350 360 370 380 390 670 680 690 700 710 720 pF1KSD SQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASARRFRFPSGAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQASRPQSFCPGCPCPGSPGHQAPRPGPSVVDAAGLRSPCPGQHGAPASARRFRFPSGAE 400 410 420 430 440 450 pF1KSD L : XP_016 L >>XP_016879732 (OMIM: 226400,605829) PREDICTED: transmem (435 aa) initn: 2712 init1: 2712 opt: 2712 Z-score: 1979.0 bits: 376.0 E(85289): 1.7e-103 Smith-Waterman score: 2712; 99.8% identity (99.8% similar) in 411 aa overlap (224-634:1-411) 200 210 220 230 240 250 pF1KSD ESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFC :::::::::::::::::::::::::::::: XP_016 MVKGLPQKTLLGQGYQAPLSAKVFSSWDFC 10 20 30 260 270 280 290 300 310 pF1KSD IRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLIGLLVVGA :::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::: XP_016 IRVQEAATIKKHEISNEFKVELEEGRRFQLMQQQTRAQTACRLLSYLRVNVLNGLLVVGA 40 50 60 70 80 90 320 330 340 350 360 370 pF1KSD ISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLT 100 110 120 130 140 150 380 390 400 410 420 430 pF1KSD LIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWENSVGEELYKLSIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDYQCWENSVGEELYKLSIF 160 170 180 190 200 210 440 450 460 470 480 490 pF1KSD NFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVTWMGLFYCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVLDIVAGQTVTWMGLFYCP 220 230 240 250 260 270 500 510 520 530 540 550 pF1KSD LLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLLGLLLAAVPLGYVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSSTFFFQLVLLLGLLLAAVPLGYVV 280 290 300 310 320 330 560 570 580 590 600 610 pF1KSD SSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLIMLSLVLTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRALHYLGSHAFSFPLLIMLSLVLTV 340 350 360 370 380 390 620 630 640 650 660 670 pF1KSD CVSQTQANARAIHRLRKQLVWQVQEKWHLVEDLSRLLPEPGPSDSPGPKYPASQASRPQS ::::::::::::::::::::: XP_016 CVSQTQANARAIHRLRKQLVWVSVLGAGEGTAASVETLPYVWPRA 400 410 420 430 >>XP_016879730 (OMIM: 226400,605829) PREDICTED: transmem (491 aa) initn: 1878 init1: 1848 opt: 2671 Z-score: 1948.6 bits: 370.6 E(85289): 8.4e-102 Smith-Waterman score: 2671; 98.5% identity (98.5% similar) in 409 aa overlap (1-405:1-409) 10 20 30 40 50 60 pF1KSD MLLPWSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT :::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MLLPRSVSSERAPGVPEPEELWEAEMERLRGSGTPVRGLPYAMMDKRLIWQLREPAGVQT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KSD LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRWQRWQRRRQTVERRLREAAQRLARGLGLWEGALYEIGGLFGTGIRSYFTFLRFLLLLN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KSD LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLSLLLTASFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLRFHNQLWHVLTGRAFT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KSD NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTYLFYGAYRVGPESSSVYSIRLAYLLSPLACLLLCFCGTLRRMVKGLPQKTLLGQGYQA 190 200 210 220 230 240 250 260 270 280 290 pF1KSD PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKV----ELEEGRRFQLMQQQTRAQTACRL ::::::::::::::::::::::::::::::::: ::::::::::::::::::::::: XP_016 PLSAKVFSSWDFCIRVQEAATIKKHEISNEFKVCARVELEEGRRFQLMQQQTRAQTACRL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KSD LSYLRVNVLIGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT ::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSYLRVNVLNGLLVVGAISAIFWATKYSQDNKEESLFLLLQYLPPGVIALVNFLGPLLFT 310 320 330 340 350 360 360 370 380 390 400 410 pF1KSD FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSCESYGYNVCDY ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLVQLENYPPNTEVNLTLIWCVVLKLASLGMFSVSLGQTILCIGRDKSSLLGELRGGGAV 370 380 390 400 410 420 420 430 440 450 460 470 pF1KSD QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAWLEREEFLVPKNVL XP_016 QAEYLQLPPHRGLRLPGHPASEAAGGPVLRPVLGLAGTGGVPGPQECAGHRGGADGHLDG 430 440 450 460 470 480 726 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 09:01:43 2016 done: Thu Nov 3 09:01:45 2016 Total Scan time: 13.810 Total Display time: 0.210 Function used was FASTA [36.3.4 Apr, 2011]