Gene/Protein Characteristic Table for KIAA0405
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Product ID ORK00067
Accession No AB007865
Description fibronectin leucine rich transmembrane protein 2
Clone name hg01274
Vector information
The cDNA fragment was inserted at the SalI-NotI site of the ...
cDNA sequence DNA sequence (7527 bp)
Predicted protein sequence (706 aa)
Flexi ORF Clone FXC00067
Source Human adult brain
Rouge ID mKIAA0405 by Kazusa Mouse cDNA Project
Features of the cloned cDNA sequence
Description

Length: 7527 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis).

N-terminal truncation Coding interruption
cloned DNA seq No warning No warning
Features of the protein sequence
Description

Length: 706 aa
Result of homology search against nr database (FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
XP_547942 0 94.5 similar to Leuc...
Canis lupus fam...
O43155 0 100.0 Leucine-rich re...
Homo sapiens
AAI43937 0 99.8 FLRT2 protein [...
Homo sapiens
XP_001106330 0 99.5 fibronectin leu...
Macaca mulatta
BAG51774 0 99.5 unnamed protein...
Homo sapiens
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of homology search against HUGE database (FASTA output, Multiple alignment)
Entry Exp ID% HUGE_ID
AB040902 3.8e-57 47.1 KIAA1469
AB046800 1.5e-10 30.0 KIAA1580
AB040930 1.1e-08 24.0 KIAA1497
AB040898 1.4e-07 26.2 KIAA1465
AB020655 8.2e-07 28.2 KIAA0848
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)

Result of InterProScan

Search method interpro_ID From To Entry Definition
FPrintScan IPR001611 207 220 PR00019 Leucine-rich repeat
IPR001611 321 334 PR00019 Leucine-rich repeat
HMMPfam IPR000372 81 108 PF01462 Leucine-rich repeat
IPR001611 110 133 PF00560 Leucine-rich repeat
IPR001611 156 178 PF00560 Leucine-rich repeat
IPR001611 180 204 PF00560 Leucine-rich repeat
IPR001611 206 224 PF00560 Leucine-rich repeat
IPR001611 227 249 PF00560 Leucine-rich repeat
IPR001611 251 275 PF00560 Leucine-rich repeat
IPR001611 277 298 PF00560 Leucine-rich repeat
IPR001611 299 321 PF00560 Leucine-rich repeat
IPR001611 323 345 PF00560 Leucine-rich repeat
IPR000483 382 407 PF01463 Cysteine-rich flanking region
IPR003961 466 548 PF00041 Fibronectin
HMMSmart IPR000372 81 113 SM00013 Leucine-rich repeat
IPR003591 153 177 SM00369 Leucine-rich repeat
IPR003591 178 203 SM00369 Leucine-rich repeat
IPR003591 205 227 SM00369 Leucine-rich repeat
IPR003591 228 248 SM00369 Leucine-rich repeat
IPR003591 249 274 SM00369 Leucine-rich repeat
IPR003591 298 320 SM00369 Leucine-rich repeat
IPR003591 321 344 SM00369 Leucine-rich repeat
IPR000483 356 407 SM00082 Cysteine-rich flanking region
ProfileScan IPR003961 466 556 PS50853 Fibronectin
ScanRegExp IPR013090 85 95 PS00119 Phospholipase A2

Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length
SOSUI2 1 20 SHFDFAVYFFFSFSFSHHIVFYF 42 SECONDARY 23
2 479 NDTSIQVSWLSLFTVMAYKLTWV 501 SECONDARY 23
3 586 PFLLAGLIGGAVIFVLVVLLSVF 608 PRIMARY 23
Expression profile
Description

RT-PCR
Experimental conditions
Primer_f AATCTTTCAGCCCCTTATCAG
Primer_r AGGGGCATTTGTAAAGGTGTC
PCR conditions 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RH mapping information
Description

Chromosome No. 14
Experimental conditions
Panel name GeneBridge 4
Primer_f AATCTTTCAGCCCCTTATCAG
Primer_r AGGGGCATTTGTAAAGGTGTC
PCR product length 204 bp
PCR conditions 95 °C15 sec62 °C60 sec30 cycles
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