HUGE

Gene/Protein Characteristic Table for KIAA0315

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Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK00501
Accession No. :	AB002313
Description :	Plexin-B2 precursor.
HUGO Gene Name :	plexin B2 (PLXNB2)
Clone Name :	hg00246 [Vector Info]
Flexi ORF Clone :	pF1KSDA0315
Source :	Human adult brain

Features of the cloned DNA sequence	Description

Length: 6252 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Features of the protein sequence	Description

Length: 1841 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
O15031	100.0	Plexin-B2; MM1;...	Homo sapiens
CAH91205	98.3	hypothetical pr...	Pongo abelii
EDL76549	88.0	plexin B2 [Ratt...	Rattus norvegicus
EDL04367	87.4	mCG140951 [Mus ...	Mus musculus
BAE27981	87.4	unnamed protein...	Mus musculus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB014520	2.2e-98	34.7	KIAA0620
AB007867	9.4e-83	39.3	KIAA0407
AB007932	3.9e-54	33.2	KIAA0463
AB046770	1.8e-53	35.3	KIAA1550
AB033032	1.2e-47	40.8	KIAA1206

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

HMMPfam IPR001627 37 452 PF01403 Semaphorin/CD100 antigen

IPR002165 471 522 PF01437 Plexin

IPR002165 762 804 PF01437 Plexin

IPR002909 806 895 PF01833 Cell surface receptor IPT/TIG

IPR002909 898 981 PF01833 Cell surface receptor IPT/TIG

IPR002909 986 1094 PF01833 Cell surface receptor IPT/TIG

IPR013548 1273 1808 PF08337 Plexin cytoplasmic region

HMMSmart IPR001627 37 453 SM00630 Semaphorin/CD100 antigen

IPR003659 471 522 SM00423 Plexin/semaphorin/integrin

IPR003659 617 670 SM00423 Plexin/semaphorin/integrin

IPR003659 762 804 SM00423 Plexin/semaphorin/integrin

IPR002909 805 896 SM00429 Cell surface receptor IPT/TIG

IPR002909 897 983 SM00429 Cell surface receptor IPT/TIG

IPR002909 985 1095 SM00429 Cell surface receptor IPT/TIG

ProfileScan IPR001627 11 469 PS51004 Semaphorin/CD100 antigen

Search method	interpro_ID	From	To	Entry	Definition
HMMPfam	IPR001627	37	452	PF01403	Semaphorin/CD100 antigen
IPR002165	471	522	PF01437	Plexin
IPR002165	762	804	PF01437	Plexin
IPR002909	806	895	PF01833	Cell surface receptor IPT/TIG
IPR002909	898	981	PF01833	Cell surface receptor IPT/TIG
IPR002909	986	1094	PF01833	Cell surface receptor IPT/TIG
IPR013548	1273	1808	PF08337	Plexin cytoplasmic region
HMMSmart	IPR001627	37	453	SM00630	Semaphorin/CD100 antigen
IPR003659	471	522	SM00423	Plexin/semaphorin/integrin
IPR003659	617	670	SM00423	Plexin/semaphorin/integrin
IPR003659	762	804	SM00423	Plexin/semaphorin/integrin
IPR002909	805	896	SM00429	Cell surface receptor IPT/TIG
IPR002909	897	983	SM00429	Cell surface receptor IPT/TIG
IPR002909	985	1095	SM00429	Cell surface receptor IPT/TIG
ProfileScan	IPR001627	11	469	PS51004	Semaphorin/CD100 antigen

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 3 AMALQLWALTLLGLLGAGASLR 24 PRIMARY 22

2 1199 VPLSLILPLVIVPMVVVIAVSV 1220 PRIMARY 22

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	3	AMALQLWALTLLGLLGAGASLR	24	PRIMARY	22
2	1199	VPLSLILPLVIVPMVVVIAVSV	1220	PRIMARY	22

Expression profile	Description

: RT-PCR Description

Experimental conditions

Primer_f
: ACTTGACCTTTGACGTGGGGC

Primer_r
: ACGATGCCTTCCTGACCTCAC

PCR conditions
: 95 °C15 sec64 °C15 sec72 °C45 sec30 cycles

RT-PCR	Description

RH mapping information	Description

Chromosome No.

: 22

Experimental conditions

Panel name	: GeneBridge 4
Primer_f	: ACTTGACCTTTGACGTGGGGC
Primer_r	: ACGATGCCTTCCTGACCTCAC
PCR product length	: 90 bp
PCR conditions	: 95 °C15 sec66 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Gene/Protein Characteristic Table for KIAA0315

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information