HUGE

Gene/Protein Characteristic Table for KIAA0822

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK04008
Accession No. :	AB020629
Description :	ATP-binding cassette sub-family A member 8.
HUGO Gene Name :	ATP-binding cassette, sub-family A (ABC1), member 8 (ABCA8)
Clone Name :	hh02681 [Vector Info]
Source :	Human adult brain

Features of the cloned DNA sequence	Description

Length: 5677 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
NO

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 793 bp

Genome contig ID gi51511734r_64275028
PolyA signal sequence
(AATAAA,-25)
+----*----+----*----+----*----+----
GAAAATGTGAAATAAATCTCATATATATAGTTTTG
Flanking genome sequence
(100000 - 99951)
----+----*----+----*----+----*----+----*----+----*
AAATACGTTTTCTATTTCATGTGTCTTTTTCTTAACTCGGTGGCTTCCTG

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 17 r 64375028 64463087 38 99.8 Perfect prediction

Features of the protein sequence	Description

Length: 1591 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
O94911	100.0	ATP-binding cas...	Homo sapiens
XP_001082492	96.7	similar to ATP-...	Macaca mulatta
AAI30281	97.5	ABCA8 protein [...	Homo sapiens
EAW89076	57.5	hCG2039659, iso...	Homo sapiens
CAM13339	70.5	ATP-binding cas...	Mus musculus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB067475	1.6e-87	42.1	KIAA1888
AB028985	4.5e-13	26.1	KIAA1062

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

[ zoom out (x2) ]

Result of InterProScan

Search method interpro_ID From To Entry Definition

BlastProDom IPR003439 604 629 PD000006 ABC transporter related

IPR003439 1387 1430 PD000006 ABC transporter related

HMMPfam IPR003439 519 661 PF00005 ABC transporter related

IPR003439 1286 1464 PF00005 ABC transporter related

HMMSmart IPR003593 518 662 SM00382 AAA+ ATPase

IPR003593 1285 1465 SM00382 AAA+ ATPase

ProfileScan IPR003439 490 685 PS50893 ABC transporter related

IPR003439 1255 1488 PS50893 ABC transporter related

Search method	interpro_ID	From	To	Entry	Definition
BlastProDom	IPR003439	604	629	PD000006	ABC transporter related
IPR003439	1387	1430	PD000006	ABC transporter related
HMMPfam	IPR003439	519	661	PF00005	ABC transporter related
IPR003439	1286	1464	PF00005	ABC transporter related
HMMSmart	IPR003593	518	662	SM00382	AAA+ ATPase
IPR003593	1285	1465	SM00382	AAA+ ATPase
ProfileScan	IPR003439	490	685	PS50893	ABC transporter related
IPR003439	1255	1488	PS50893	ABC transporter related

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 39 ESLMEWLNSLLLLLCLYIYPHSH 61 PRIMARY 23

2 231 ITDLYLFSCIISFSSFIYYASV 252 PRIMARY 22

3 275 FWLSWGLLYAGFIFIMALFLALV 297 PRIMARY 23

4 306 LSGFMVVFSLFLLYGLSLVALAF 328 PRIMARY 23

5 337 SFLTGLVVFLLTVFWGCLGFTSL 359 PRIMARY 23

6 367 LEWILSLLSPFAFMLGMAQLLHL 389 SECONDARY 23

7 407 LIVATNFMLAFDTCLYLALAIYF 429 SECONDARY 23

8 832 ALLALLLILMAGFCPLLVEYTMV 854 PRIMARY 23

9 985 QDNPIGFLAYIMFWLVLTSSCPP 1007 SECONDARY 23

10 1037 FGQALVDVSLYFLVFVFIYLMSY 1059 PRIMARY 23

11 1071 IHIIQIPCAVGYSFSLIFMTYVI 1093 PRIMARY 23

12 1105 GIWSFCFYVVTVFSVAGFAFSIF 1127 PRIMARY 23

13 1136 TFLIPPATMIGCLFLSSHLLFSS 1158 SECONDARY 23

14 1167 VQPFLVFLIPFLHFIIFLFTLRC 1189 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	39	ESLMEWLNSLLLLLCLYIYPHSH	61	PRIMARY	23
2	231	ITDLYLFSCIISFSSFIYYASV	252	PRIMARY	22
3	275	FWLSWGLLYAGFIFIMALFLALV	297	PRIMARY	23
4	306	LSGFMVVFSLFLLYGLSLVALAF	328	PRIMARY	23
5	337	SFLTGLVVFLLTVFWGCLGFTSL	359	PRIMARY	23
6	367	LEWILSLLSPFAFMLGMAQLLHL	389	SECONDARY	23
7	407	LIVATNFMLAFDTCLYLALAIYF	429	SECONDARY	23
8	832	ALLALLLILMAGFCPLLVEYTMV	854	PRIMARY	23
9	985	QDNPIGFLAYIMFWLVLTSSCPP	1007	SECONDARY	23
10	1037	FGQALVDVSLYFLVFVFIYLMSY	1059	PRIMARY	23
11	1071	IHIIQIPCAVGYSFSLIFMTYVI	1093	PRIMARY	23
12	1105	GIWSFCFYVVTVFSVAGFAFSIF	1127	PRIMARY	23
13	1136	TFLIPPATMIGCLFLSSHLLFSS	1158	SECONDARY	23
14	1167	VQPFLVFLIPFLHFIIFLFTLRC	1189	PRIMARY	23

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: TTTCTGTAAGCCAACTGTGTG

Primer_r
: TTCTACCTACTCAGTCATGTG

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 17

Experimental conditions

Panel name	: GeneBridge 4
Primer_f	: TTTCTGTAAGCCAACTGTGTG
Primer_r	: TTCTACCTACTCAGTCATGTG
PCR product length	: 153 bp
PCR conditions	: 95 °C15 sec62 °C60 sec35 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	NO
Warning for coding interruption:	NO

Length of 3'UTR	793 bp
Genome contig ID	gi51511734r_64275028
PolyA signal sequence (AATAAA,-25)	+--------+--------+----*----+---- GAAAATGTGAAATAAATCTCATATATATAGTTTTG
Flanking genome sequence (100000 - 99951)	----+--------+--------+--------+--------+----* AAATACGTTTTCTATTTCATGTGTCTTTTTCTTAACTCGGTGGCTTCCTG

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	17	r	64375028	64463087	38	99.8	Perfect prediction

Gene/Protein Characteristic Table for KIAA0822

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information