HUGE

Gene/Protein Characteristic Table for KIAA1062

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK04006
Accession No. :	AB028985
Description :	ATP-binding cassette sub-family A member 2.
HUGO Gene Name :
Clone Name :	hj03579s1 [Vector Info]
Flexi ORF Clone :	pF1KA1062
Source :	Human adult brain
Note :	We replaced hj03579, former representative clones for KIAA1062 with hj03579s1. (2002/5/10)

Features of the cloned DNA sequence	Description

Length: 6011 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 695 bp

Genome contig ID gi89161216r_138921507
PolyA signal sequence
(AATAAA,-15)
+----*----+----*----+----*----+----
ACAGATGTTTGTTTTAAATAAATAAACAAAATGTC
Flanking genome sequence
(100000 - 99951)
----+----*----+----*----+----*----+----*----+----*
TGCGGGTCTGCGTGTGTGGGTTGGGAAGGGTGGGGAGGATGGGCGCATCA

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 9 r 139021507 139032346 35 99.8 Perfect prediction

Features of the protein sequence	Description

Length: 1771 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
Q9BZC7	100.0	ATP-binding cas...	Homo sapiens
AAG09372	100.0	ATP-binding cas...	Homo sapiens
NP_001597	100.0	ATP-binding cas...	Homo sapiens
NP_997698	100.0	ATP-binding cas...	Homo sapiens
BAG10412	99.9	ATP-binding cas...	synthetic construct

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB067475	1.5e-25	28.9	KIAA1888
AB020629	2.8e-07	25.9	KIAA0822

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

BlastProDom IPR003439 458 501 PD000006 ABC transporter related

IPR003439 1521 1564 PD000006 ABC transporter related

HMMPfam IPR003439 353 533 PF00005 ABC transporter related

IPR003439 1416 1597 PF00005 ABC transporter related

HMMSmart IPR003593 352 534 SM00382 AAA+ ATPase

IPR003593 1415 1600 SM00382 AAA+ ATPase

ProfileScan IPR003439 326 557 PS50893 ABC transporter related

IPR003439 1386 1621 PS50893 ABC transporter related

ScanRegExp IPR003439 459 473 PS00211 ABC transporter related

IPR002345 759 772 PS00213 Lipocalin

IPR013032 976 987 PS00022 EGF-like region

Search method	interpro_ID	From	To	Entry	Definition
BlastProDom	IPR003439	458	501	PD000006	ABC transporter related
IPR003439	1521	1564	PD000006	ABC transporter related
HMMPfam	IPR003439	353	533	PF00005	ABC transporter related
IPR003439	1416	1597	PF00005	ABC transporter related
HMMSmart	IPR003593	352	534	SM00382	AAA+ ATPase
IPR003593	1415	1600	SM00382	AAA+ ATPase
ProfileScan	IPR003439	326	557	PS50893	ABC transporter related
IPR003439	1386	1621	PS50893	ABC transporter related
ScanRegExp	IPR003439	459	473	PS00211	ABC transporter related
IPR002345	759	772	PS00213	Lipocalin
IPR013032	976	987	PS00022	EGF-like region

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 37 FVIEHMMPLCMVISWVYSVAMTI 59 SECONDARY 23

2 87 AWFITGFVQLSISVTALTAILKY 109 PRIMARY 23

3 120 IIWLFLAVYAVATIMFCFLVSVL 142 PRIMARY 23

4 148 LASACGGIIYFLSYVPYMYVAIR 170 PRIMARY 23

5 183 KCIASLMSTTAFGLGSKYFALYE 205 SECONDARY 23

6 226 FNLLLAVTMLMVDAVVYGILTWY 248 PRIMARY 23

7 1123 LQGTDVVIAIFIIVAMSFVPASF 1145 PRIMARY 23

8 1172 WLANYVWDMLNYLVPATCCVIIL 1194 PRIMARY 23

9 1209 PAVLSLFLLYGWSITPIMYPASF 1231 PRIMARY 23

10 1240 YVFLIVINLFIGITATVATFLLQ 1262 PRIMARY 23

11 1270 LKVVNSYLKSCFLIFPNYNLGHG 1292 SECONDARY 23

12 1323 IVTRGLVAMAVEGVVGFLLTIMC 1345 SECONDARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	37	FVIEHMMPLCMVISWVYSVAMTI	59	SECONDARY	23
2	87	AWFITGFVQLSISVTALTAILKY	109	PRIMARY	23
3	120	IIWLFLAVYAVATIMFCFLVSVL	142	PRIMARY	23
4	148	LASACGGIIYFLSYVPYMYVAIR	170	PRIMARY	23
5	183	KCIASLMSTTAFGLGSKYFALYE	205	SECONDARY	23
6	226	FNLLLAVTMLMVDAVVYGILTWY	248	PRIMARY	23
7	1123	LQGTDVVIAIFIIVAMSFVPASF	1145	PRIMARY	23
8	1172	WLANYVWDMLNYLVPATCCVIIL	1194	PRIMARY	23
9	1209	PAVLSLFLLYGWSITPIMYPASF	1231	PRIMARY	23
10	1240	YVFLIVINLFIGITATVATFLLQ	1262	PRIMARY	23
11	1270	LKVVNSYLKSCFLIFPNYNLGHG	1292	SECONDARY	23
12	1323	IVTRGLVAMAVEGVVGFLLTIMC	1345	SECONDARY	23

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: CAGGGACTCAACAATGGGGAC

Primer_r
: AAAGCAGGGCAAGGGTGTACG

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 9

Experimental conditions

Panel name	: GeneBridge 4
Primer_f	: CAGGGACTCAACAATGGGGAC
Primer_r	: AAAGCAGGGCAAGGGTGTACG
PCR product length	: 188 bp
PCR conditions	: 95 °C15 sec66 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Length of 3'UTR	695 bp
Genome contig ID	gi89161216r_138921507
PolyA signal sequence (AATAAA,-15)	+--------+--------+----*----+---- ACAGATGTTTGTTTTAAATAAATAAACAAAATGTC
Flanking genome sequence (100000 - 99951)	----+--------+--------+--------+--------+----* TGCGGGTCTGCGTGTGTGGGTTGGGAAGGGTGGGGAGGATGGGCGCATCA

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	9	r	139021507	139032346	35	99.8	Perfect prediction

Gene/Protein Characteristic Table for KIAA1062

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information