HUGE

Gene/Protein Characteristic Table for KIAA0550

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK00559
Accession No. :	AB011122
Description :	Brain-specific angiogenesis inhibitor 3 precursor.
HUGO Gene Name :	brain-specific angiogenesis inhibitor 3 (BAI3)
Clone Name :	hh15909 [Vector Info]
Flexi ORF Clone :	pF1KSDA0550
Source :	Human adult brain
Note :	We replaced hh00851, former representative clones for KIAA0550 with hh15909. (2002/5/10)

Features of the cloned DNA sequence	Description

Length: 5420 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
NO

Warning for coding interruption:
YES

Integrity of 3' end

Length of 3'UTR 614 bp

Genome contig ID gi89161210f_69302564
PolyA signal sequence
(AATAAA,-17)
+----*----+----*----+----*----+----
AAAATGTTGTATGGTGTAAATAAACTTTTGTCTAC
Flanking genome sequence
(853556 - 853605)
----+----*----+----*----+----*----+----*----+----*
ATATCAGTTTTTTAGTGCATTTTATTTTGGATTTGTTGACCAGAAATTTA

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 6 f 69402564 70156118 32 99.9 Perfect prediction

Features of the protein sequence	Description

Length: 1524 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
O60242	100.0	Brain-specific ...	Homo sapiens
CAH73864	99.9	brain-specific ...	Homo sapiens
BAF82385	99.8	unnamed protein...	Homo sapiens
XP_001503435	98.7	similar to Brai...	Equus caballus
XP_538991	98.5	similar to Brai...	Canis lupus fam...

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB018311	2.8e-25	22.8	KIAA0768
AB018329	5.7e-25	26.1	KIAA0786
AB020628	4.7e-24	25.5	KIAA0821
AB040878	1.6e-20	31.9	KIAA1445
D87469	3.6e-20	24.8	KIAA0279

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

[ zoom out (x2) ]

Result of InterProScan

Search method interpro_ID From To Entry Definition

FPrintScan IPR008077 57 74 PR01694 Brain-specific angiogenesis inhibitor

IPR008077 539 551 PR01694 Brain-specific angiogenesis inhibitor

IPR008077 559 575 PR01694 Brain-specific angiogenesis inhibitor

IPR008077 616 635 PR01694 Brain-specific angiogenesis inhibitor

IPR008077 658 667 PR01694 Brain-specific angiogenesis inhibitor

IPR008077 719 740 PR01694 Brain-specific angiogenesis inhibitor

IPR000832 881 905 PR00249 GPCR

IPR008077 905 915 PR01694 Brain-specific angiogenesis inhibitor

IPR000832 945 968 PR00249 GPCR

IPR008077 969 982 PR01694 Brain-specific angiogenesis inhibitor

IPR000832 982 1007 PR00249 GPCR

IPR008077 1008 1025 PR01694 Brain-specific angiogenesis inhibitor

IPR000832 1025 1050 PR00249 GPCR

IPR000832 1100 1120 PR00249 GPCR

IPR008077 1121 1131 PR01694 Brain-specific angiogenesis inhibitor

IPR000832 1131 1152 PR00249 GPCR

IPR008077 1185 1198 PR01694 Brain-specific angiogenesis inhibitor

IPR008077 1413 1427 PR01694 Brain-specific angiogenesis inhibitor

IPR008077 1430 1444 PR01694 Brain-specific angiogenesis inhibitor

HMMPfam IPR000884 297 344 PF00090 Thrombospondin

IPR000884 351 399 PF00090 Thrombospondin

IPR000884 406 454 PF00090 Thrombospondin

IPR000884 461 509 PF00090 Thrombospondin

IPR001879 513 574 PF02793 Hormone receptor

IPR000203 817 865 PF01825 GPS

IPR000832 876 1156 PF00002 GPCR

HMMSmart IPR000884 296 345 SM00209 Thrombospondin

IPR000884 350 400 SM00209 Thrombospondin

IPR000884 405 455 SM00209 Thrombospondin

IPR000884 460 510 SM00209 Thrombospondin

IPR001879 512 578 SM00008 Hormone receptor

IPR000203 817 870 SM00303 GPS

ProfileScan IPR000859 32 161 PS01180 CUB

IPR000884 293 345 PS50092 Thrombospondin

IPR000884 347 400 PS50092 Thrombospondin

IPR000884 402 455 PS50092 Thrombospondin

IPR000884 457 510 PS50092 Thrombospondin

IPR001879 493 573 PS50227 Hormone receptor

IPR000203 818 870 PS50221 GPS

IPR000832 879 1153 PS50261 GPCR

ScanRegExp IPR000832 1141 1156 PS00650 GPCR

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR008077	57	74	PR01694	Brain-specific angiogenesis inhibitor
IPR008077	539	551	PR01694	Brain-specific angiogenesis inhibitor
IPR008077	559	575	PR01694	Brain-specific angiogenesis inhibitor
IPR008077	616	635	PR01694	Brain-specific angiogenesis inhibitor
IPR008077	658	667	PR01694	Brain-specific angiogenesis inhibitor
IPR008077	719	740	PR01694	Brain-specific angiogenesis inhibitor
IPR000832	881	905	PR00249	GPCR
IPR008077	905	915	PR01694	Brain-specific angiogenesis inhibitor
IPR000832	945	968	PR00249	GPCR
IPR008077	969	982	PR01694	Brain-specific angiogenesis inhibitor
IPR000832	982	1007	PR00249	GPCR
IPR008077	1008	1025	PR01694	Brain-specific angiogenesis inhibitor
IPR000832	1025	1050	PR00249	GPCR
IPR000832	1100	1120	PR00249	GPCR
IPR008077	1121	1131	PR01694	Brain-specific angiogenesis inhibitor
IPR000832	1131	1152	PR00249	GPCR
IPR008077	1185	1198	PR01694	Brain-specific angiogenesis inhibitor
IPR008077	1413	1427	PR01694	Brain-specific angiogenesis inhibitor
IPR008077	1430	1444	PR01694	Brain-specific angiogenesis inhibitor
HMMPfam	IPR000884	297	344	PF00090	Thrombospondin
IPR000884	351	399	PF00090	Thrombospondin
IPR000884	406	454	PF00090	Thrombospondin
IPR000884	461	509	PF00090	Thrombospondin
IPR001879	513	574	PF02793	Hormone receptor
IPR000203	817	865	PF01825	GPS
IPR000832	876	1156	PF00002	GPCR
HMMSmart	IPR000884	296	345	SM00209	Thrombospondin
IPR000884	350	400	SM00209	Thrombospondin
IPR000884	405	455	SM00209	Thrombospondin
IPR000884	460	510	SM00209	Thrombospondin
IPR001879	512	578	SM00008	Hormone receptor
IPR000203	817	870	SM00303	GPS
ProfileScan	IPR000859	32	161	PS01180	CUB
IPR000884	293	345	PS50092	Thrombospondin
IPR000884	347	400	PS50092	Thrombospondin
IPR000884	402	455	PS50092	Thrombospondin
IPR000884	457	510	PS50092	Thrombospondin
IPR001879	493	573	PS50227	Hormone receptor
IPR000203	818	870	PS50221	GPS
IPR000832	879	1153	PS50261	GPCR
ScanRegExp	IPR000832	1141	1156	PS00650	GPCR

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 5 AVRNLLIYIFSTYLLVMFGFNAA 27 PRIMARY 23

2 881 VTLIVGSGLSCLALITLAVVYAA 903 PRIMARY 23

3 912 RSIILINFCLSIISSNILILVG 933 SECONDARY 22

4 943 CTTTTAFLHFFFLASFCWVLTEA 965 SECONDARY 23

5 985 FLCLGWGLPALVVATSVGF 1003 SECONDARY 19

6 1025 YAFVGPAAAVVLVNMVIGILVFN 1047 PRIMARY 23

7 1101 LWSSCVVLPLLALTWMSAVLAMT 1123 PRIMARY 23

8 1130 FQILFAVFDSLQGFVIVMVHCIL 1152 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	5	AVRNLLIYIFSTYLLVMFGFNAA	27	PRIMARY	23
2	881	VTLIVGSGLSCLALITLAVVYAA	903	PRIMARY	23
3	912	RSIILINFCLSIISSNILILVG	933	SECONDARY	22
4	943	CTTTTAFLHFFFLASFCWVLTEA	965	SECONDARY	23
5	985	FLCLGWGLPALVVATSVGF	1003	SECONDARY	19
6	1025	YAFVGPAAAVVLVNMVIGILVFN	1047	PRIMARY	23
7	1101	LWSSCVVLPLLALTWMSAVLAMT	1123	PRIMARY	23
8	1130	FQILFAVFDSLQGFVIVMVHCIL	1152	PRIMARY	23

Expression profile	Description

: RT-PCR Description

Experimental conditions

Primer_f
: ATCATTTCACATACCTCCTGC

Primer_r
: GGATAAGGATGAGGAGGGGAC

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR	Description

RH mapping information	Description

Chromosome No.

: 6

Experimental conditions

Panel name	: GeneBridge 4
Primer_f	: ATCATTTCACATACCTCCTGC
Primer_r	: GGATAAGGATGAGGAGGGGAC
PCR product length	: 127 bp
PCR conditions	: 95 °C15 sec64 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	NO
Warning for coding interruption:	YES

Length of 3'UTR	614 bp
Genome contig ID	gi89161210f_69302564
PolyA signal sequence (AATAAA,-17)	+--------+--------+----*----+---- AAAATGTTGTATGGTGTAAATAAACTTTTGTCTAC
Flanking genome sequence (853556 - 853605)	----+--------+--------+--------+--------+----* ATATCAGTTTTTTAGTGCATTTTATTTTGGATTTGTTGACCAGAAATTTA

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	6	f	69402564	70156118	32	99.9	Perfect prediction

Gene/Protein Characteristic Table for KIAA0550

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information