HUGE

Gene/Protein Characteristic Table for KIAA0786

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Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK05864
Accession No. :	AB018329
Description :	Latrophilin-2 precursor.
HUGO Gene Name :	latrophilin 2 (LPHN2)
Clone Name :	hk05490 [Vector Info]
Source :	Human adult brain

Features of the cloned DNA sequence	Description

Length: 4345 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Features of the protein sequence	Description

Length: 1021 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
O95490	100.0	Latrophilin-2; ...	Homo sapiens
XP_001170260	99.7	latrophilin 2 i...	Pan troglodytes
XP_001170200	98.9	latrophilin 2 i...	Pan troglodytes
AAD05318	98.4	latrophilin 2 s...	Bos taurus
EAX06329	99.8	latrophilin 2, ...	Homo sapiens

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB020628	1.6e-209	63.2	KIAA0821
AB018311	2.5e-127	56.1	KIAA0768
D87469	1.3e-32	27.2	KIAA0279
AB011536	6.2e-28	26.4	KIAA0812
AB011122	1.2e-23	26.2	KIAA0550

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

FPrintScan IPR000832 411 435 PR00249 GPCR

IPR003924 436 451 PR01444 Latrophilin receptor

IPR000832 474 497 PR00249 GPCR

IPR000832 554 579 PR00249 GPCR

IPR000832 628 649 PR00249 GPCR

IPR003924 650 662 PR01444 Latrophilin receptor

HMMPfam IPR001879 28 88 PF02793 Hormone receptor

IPR000203 346 393 PF01825 GPS

IPR000832 406 653 PF00002 GPCR

IPR003334 663 1021 PF02354 Latrophilin

HMMSmart IPR001879 27 92 SM00008 Hormone receptor

IPR000203 346 398 SM00303 GPS

ProfileScan IPR001879 30 87 PS50227 Hormone receptor

IPR000203 347 398 PS50221 GPS

IPR000832 409 650 PS50261 GPCR

ScanRegExp IPR000832 638 653 PS00650 GPCR

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR000832	411	435	PR00249	GPCR
IPR003924	436	451	PR01444	Latrophilin receptor
IPR000832	474	497	PR00249	GPCR
IPR000832	554	579	PR00249	GPCR
IPR000832	628	649	PR00249	GPCR
IPR003924	650	662	PR01444	Latrophilin receptor
HMMPfam	IPR001879	28	88	PF02793	Hormone receptor
IPR000203	346	393	PF01825	GPS
IPR000832	406	653	PF00002	GPCR
IPR003334	663	1021	PF02354	Latrophilin
HMMSmart	IPR001879	27	92	SM00008	Hormone receptor
IPR000203	346	398	SM00303	GPS
ProfileScan	IPR001879	30	87	PS50227	Hormone receptor
IPR000203	347	398	PS50221	GPS
IPR000832	409	650	PS50261	GPCR
ScanRegExp	IPR000832	638	653	PS00650	GPCR

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 409 LTVITWVGIVISLVCLAICIFTF 431 PRIMARY 23

2 443 TIHKNLCINLFIAEFIFLIGIDK 465 SECONDARY 23

3 477 GLLHFFFLAAFAWMCLEGVQLYL 499 PRIMARY 23

4 515 YYVAGYLFPATVVGVSAAID 534 SECONDARY 20

5 555 SFIGPVTFIILLNIIFLVITLCK 577 PRIMARY 23

6 596 KSWVLGAFALLCLLGLTWSFGLL 618 PRIMARY 23

7 627 MAYLFTIFNAFQGVFIFIFHCAL 649 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	409	LTVITWVGIVISLVCLAICIFTF	431	PRIMARY	23
2	443	TIHKNLCINLFIAEFIFLIGIDK	465	SECONDARY	23
3	477	GLLHFFFLAAFAWMCLEGVQLYL	499	PRIMARY	23
4	515	YYVAGYLFPATVVGVSAAID	534	SECONDARY	20
5	555	SFIGPVTFIILLNIIFLVITLCK	577	PRIMARY	23
6	596	KSWVLGAFALLCLLGLTWSFGLL	618	PRIMARY	23
7	627	MAYLFTIFNAFQGVFIFIFHCAL	649	PRIMARY	23

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: CTCTTTGAAGCCAGTTATGTC

Primer_r
: AAGTTTGTGAGAAGTGCCCAG

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 1

Experimental conditions

Panel name	: UniGene
Primer_f	: -
Primer_r	: -
PCR product length	: -
PCR conditions	: -

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Primer_f	: CTCTTTGAAGCCAGTTATGTC
Primer_r	: AAGTTTGTGAGAAGTGCCCAG
PCR conditions	: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

Gene/Protein Characteristic Table for KIAA0786

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information