HUGE

Gene/Protein Characteristic Table for KIAA0768

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK05865
Accession No. :	AB018311
Description :	Latrophilin-3 precursor.
HUGO Gene Name :	latrophilin 3 (LPHN3)
Clone Name :	hk05006 [Vector Info]
Source :	Human adult brain

Features of the cloned DNA sequence	Description

Length: 4150 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Features of the protein sequence	Description

Length: 872 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
Q9HAR2	100.0	Latrophilin-3; ...	Homo sapiens
XP_001135082	99.9	latrophilin 3 i...	Pan troglodytes
BAE26219	95.4	unnamed protein...	Mus musculus
EDL89863	95.5	latrophilin 3, ...	Rattus norvegicus
AAC62660	95.5	CL3AA [Rattus n...	Rattus norvegicus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB018329	5.5e-136	56.1	KIAA0786
AB020628	3.7e-125	48.2	KIAA0821
D87469	3.2e-37	32.1	KIAA0279
AB011536	1.2e-29	29.9	KIAA0812
AB011122	9.8e-26	22.6	KIAA0550

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

FPrintScan IPR000832 291 315 PR00249 GPCR

IPR003924 316 331 PR01444 Latrophilin receptor

IPR000832 354 377 PR00249 GPCR

IPR000832 392 417 PR00249 GPCR

IPR000832 434 459 PR00249 GPCR

IPR000832 508 529 PR00249 GPCR

IPR003924 530 542 PR01444 Latrophilin receptor

HMMPfam IPR000203 226 273 PF01825 GPS

IPR000832 286 533 PF00002 GPCR

IPR003334 542 872 PF02354 Latrophilin

HMMSmart IPR000203 226 278 SM00303 GPS

ProfileScan IPR000203 227 278 PS50221 GPS

IPR000832 289 530 PS50261 GPCR

ScanRegExp IPR000832 518 533 PS00650 GPCR

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR000832	291	315	PR00249	GPCR
IPR003924	316	331	PR01444	Latrophilin receptor
IPR000832	354	377	PR00249	GPCR
IPR000832	392	417	PR00249	GPCR
IPR000832	434	459	PR00249	GPCR
IPR000832	508	529	PR00249	GPCR
IPR003924	530	542	PR01444	Latrophilin receptor
HMMPfam	IPR000203	226	273	PF01825	GPS
IPR000832	286	533	PF00002	GPCR
IPR003334	542	872	PF02354	Latrophilin
HMMSmart	IPR000203	226	278	SM00303	GPS
ProfileScan	IPR000203	227	278	PS50221	GPS
IPR000832	289	530	PS50261	GPCR
ScanRegExp	IPR000832	518	533	PS00650	GPCR

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 289 LDVITWVGILLSLVCLLICIFTF 311 PRIMARY 23

2 323 TIHKNLCISLFVAELLFLIGIN 344 SECONDARY 22

3 358 LLHFFFLAAFTWMFLEGVQLYIM 380 PRIMARY 23

4 395 FYLVGYGMPALIVAVSAAVD 414 PRIMARY 20

5 434 WSFIGPATLIIMLNVIFLGIALY 456 PRIMARY 23

6 477 SWVIGAIALLCLLGLTWAFGLMY 499 PRIMARY 23

7 507 MAYLFTIFNSLQGMFIFIFHCVL 529 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	289	LDVITWVGILLSLVCLLICIFTF	311	PRIMARY	23
2	323	TIHKNLCISLFVAELLFLIGIN	344	SECONDARY	22
3	358	LLHFFFLAAFTWMFLEGVQLYIM	380	PRIMARY	23
4	395	FYLVGYGMPALIVAVSAAVD	414	PRIMARY	20
5	434	WSFIGPATLIIMLNVIFLGIALY	456	PRIMARY	23
6	477	SWVIGAIALLCLLGLTWAFGLMY	499	PRIMARY	23
7	507	MAYLFTIFNSLQGMFIFIFHCVL	529	PRIMARY	23

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: AGCAGTTCATCACCAGGACAC

Primer_r
: TGACCTTCCAATGCTTACGAG

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 4

Experimental conditions

Panel name	: UniGene
Primer_f	: -
Primer_r	: -
PCR product length	: -
PCR conditions	: -

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Primer_f	: AGCAGTTCATCACCAGGACAC
Primer_r	: TGACCTTCCAATGCTTACGAG
PCR conditions	: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

Gene/Protein Characteristic Table for KIAA0768

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information