HUGE

Gene/Protein Characteristic Table for KIAA0891

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK01614
Accession No. :	AB020698
Description :	Ubiquitin carboxyl-terminal hydrolase 19 (Fragment).
HUGO Gene Name :	ubiquitin specific peptidase 19 (USP19)
Clone Name :	hk08201 [Vector Info]
Flexi ORF Clone :	pF1KSDA0891
Source :	Human adult brain

Features of the cloned DNA sequence	Description

Length: 4401 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 283 bp

Genome contig ID gi89161205r_49021112
PolyA signal sequence
(AATAAA,-24)
+----*----+----*----+----*----+----
TTAAAAGTGTTAATAAAACCAGACTATTCAGGCCC
Flanking genome sequence
(100000 - 99951)
----+----*----+----*----+----*----+----*----+----*
AATCTCGTCTCTCTGTCTCAACGCCGCTGCTGTCTGCGCCTGCCTTGGGA

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 3 r 49121112 49133217 26 99.9 Perfect prediction

Features of the protein sequence	Description

Length: 1371 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
XP_516454	99.2	ubiquitin speci...	Pan troglodytes
O94966	100.0	Ubiquitin carbo...	Homo sapiens
EAW64955	99.9	ubiquitin speci...	Homo sapiens
EAW64957	98.5	ubiquitin speci...	Homo sapiens
AAH82241	97.2	USP19 protein [...	Homo sapiens

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB011101	8.5e-32	35.8	KIAA0529
D29956	2.4e-21	38.1	KIAA0055
AB023220	1.4e-08	24.5	KIAA1003
AB029020	6.8e-06	22.9	KIAA1097
AB046814	1.7e-05	25.6	KIAA1594

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

HMMPfam IPR007052 169 244 PF04969 CS

IPR015054 248 546 PF08959 Domain of unknown function DUF1872

IPR001394 547 1264 PF00443 Peptidase C19

IPR002893 844 886 PF01753 Zinc finger

ProfileScan IPR007052 166 255 PS51203 CS

IPR007052 335 437 PS51203 CS

IPR001394 550 1268 PS50235 Peptidase C19

IPR002893 844 886 PS50865 Zinc finger

ScanRegExp IPR001394 551 566 PS00972 Peptidase C19

IPR002893 844 886 PS01360 Zinc finger

IPR001394 1202 1219 PS00973 Peptidase C19

Search method	interpro_ID	From	To	Entry	Definition
HMMPfam	IPR007052	169	244	PF04969	CS
IPR015054	248	546	PF08959	Domain of unknown function DUF1872
IPR001394	547	1264	PF00443	Peptidase C19
IPR002893	844	886	PF01753	Zinc finger
ProfileScan	IPR007052	166	255	PS51203	CS
IPR007052	335	437	PS51203	CS
IPR001394	550	1268	PS50235	Peptidase C19
IPR002893	844	886	PS50865	Zinc finger
ScanRegExp	IPR001394	551	566	PS00972	Peptidase C19
IPR002893	844	886	PS01360	Zinc finger
IPR001394	1202	1219	PS00973	Peptidase C19

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 1 AGCGGLARLSVPCWRIWPQRAAK 23 SECONDARY 23

2 1342 LRYFVLGTVAALVALVLNVFYPL 1364 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	1	AGCGGLARLSVPCWRIWPQRAAK	23	SECONDARY	23
2	1342	LRYFVLGTVAALVALVLNVFYPL	1364	PRIMARY	23

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: CATGCCTGCCTTTGTTGTGGG

Primer_r
: AGAGCAGCAGGATGAATGGAC

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 3

Experimental conditions

Panel name	: GeneBridge 4
Primer_f	: GCCATGCCTGCCTTTGTTGTG
Primer_r	: CAGACAGCCAGATGGATACAC
PCR product length	: 135 bp
PCR conditions	: 95 °C15 sec64 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Length of 3'UTR	283 bp
Genome contig ID	gi89161205r_49021112
PolyA signal sequence (AATAAA,-24)	+--------+--------+----*----+---- TTAAAAGTGTTAATAAAACCAGACTATTCAGGCCC
Flanking genome sequence (100000 - 99951)	----+--------+--------+--------+--------+----* AATCTCGTCTCTCTGTCTCAACGCCGCTGCTGTCTGCGCCTGCCTTGGGA

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	3	r	49121112	49133217	26	99.9	Perfect prediction

Primer_f	: CATGCCTGCCTTTGTTGTGGG
Primer_r	: AGAGCAGCAGGATGAATGGAC
PCR conditions	: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

Gene/Protein Characteristic Table for KIAA0891

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information