HUGE

Gene/Protein Characteristic Table for KIAA1079

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK00174
Accession No. :	AB029002
Description :	Serine/threonine-protein kinase LMTK2 precursor.
HUGO Gene Name :	lemur tyrosine kinase 2 (LMTK2)
Clone Name :	hj06972 [Vector Info]
Flexi ORF Clone :	pF1KA1079
Source :	Human adult brain

Features of the cloned DNA sequence	Description

Length: 4954 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
NO

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 296 bp

Genome contig ID gi89161213f_97474133
PolyA signal sequence
(None)
+----*----+----*----+----*----+----
CGGCGTCCCTCAGTGCCCCGTGCACCCGCGGCCGC
Flanking genome sequence
(198852 - 198901)
----+----*----+----*----+----*----+----*----+----*
GGCCTCCCAGGCAGTGCTCATGCGCTGGCCGTCGGGGGAGGCAGGGGCAC

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 7 f 97574133 97672983 15 99.4 Perfect prediction

Features of the protein sequence	Description

Length: 1476 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
BAG10414	100.0	serine/threonin...	synthetic construct
EAW76720	99.9	lemur tyrosine ...	Homo sapiens
Q8IWU2	99.7	Serine/threonin...	Homo sapiens
AAN08717	99.7	KPI-2 protein [...	Homo sapiens
XP_001134909	99.0	lemur tyrosine ...	Pan troglodytes

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB067470	2.7e-54	30.5	KIAA1883
AB014541	9.9e-44	34.2	KIAA0641
AB040892	9.9e-07	28.9	KIAA1459

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

BlastProDom IPR000719 162 423 PD000001 Protein kinase

FPrintScan IPR001245 236 249 PR00109 Tyrosine protein kinase

IPR001245 277 295 PR00109 Tyrosine protein kinase

IPR001245 352 374 PR00109 Tyrosine protein kinase

HMMPfam IPR001245 159 429 PF07714 Tyrosine protein kinase

HMMSmart IPR001245 159 429 SM00219 Tyrosine protein kinase

IPR002290 159 432 SM00220 Serine/threonine protein kinase

ProfileScan IPR000719 159 429 PS50011 Protein kinase

ScanRegExp IPR000719 165 190 PS00107 Protein kinase

IPR008266 283 295 PS00109 Tyrosine protein kinase

Search method	interpro_ID	From	To	Entry	Definition
BlastProDom	IPR000719	162	423	PD000001	Protein kinase
FPrintScan	IPR001245	236	249	PR00109	Tyrosine protein kinase
IPR001245	277	295	PR00109	Tyrosine protein kinase
IPR001245	352	374	PR00109	Tyrosine protein kinase
HMMPfam	IPR001245	159	429	PF07714	Tyrosine protein kinase
HMMSmart	IPR001245	159	429	SM00219	Tyrosine protein kinase
IPR002290	159	432	SM00220	Serine/threonine protein kinase
ProfileScan	IPR000719	159	429	PS50011	Protein kinase
ScanRegExp	IPR000719	165	190	PS00107	Protein kinase
IPR008266	283	295	PS00109	Tyrosine protein kinase

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 32 RLLLLLLVLLIAGSAGAAPLP 52 PRIMARY 21

2 68 SFVILCVCSLIILIVLIANCVSC 90 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	32	RLLLLLLVLLIAGSAGAAPLP	52	PRIMARY	21
2	68	SFVILCVCSLIILIVLIANCVSC	90	PRIMARY	23

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: GAACGAACTCCTTGCCTACAC

Primer_r
: TGAGGCTATGCAGGTTGAAGG

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 7

Experimental conditions

Panel name	: GeneBridge 4
Primer_f	: TTGCCAGCTTTTCCCTCACAC
Primer_r	: TCTTCCTCCCAATCTCATGTC
PCR product length	: 198 bp
PCR conditions	: 95 °C15 sec64 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	NO
Warning for coding interruption:	NO

Length of 3'UTR	296 bp
Genome contig ID	gi89161213f_97474133
PolyA signal sequence (None)	+--------+--------+----*----+---- CGGCGTCCCTCAGTGCCCCGTGCACCCGCGGCCGC
Flanking genome sequence (198852 - 198901)	----+--------+--------+--------+--------+----* GGCCTCCCAGGCAGTGCTCATGCGCTGGCCGTCGGGGGAGGCAGGGGCAC

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	7	f	97574133	97672983	15	99.4	Perfect prediction

Primer_f	: GAACGAACTCCTTGCCTACAC
Primer_r	: TGAGGCTATGCAGGTTGAAGG
PCR conditions	: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

Gene/Protein Characteristic Table for KIAA1079

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information