HUGE

Gene/Protein Characteristic Table for KIAA1260

Link to : GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK00786
Accession No. :	AB033086
Description :	Neuroligin-4, X-linked precursor.
HUGO Gene Name :	neuroligin 4, X-linked (NLGN4X)
Clone Name :	hh15752 [Vector Info]
Flexi ORF Clone :	pF1KSDA1260
Source :	Human adult brain

Features of the cloned DNA sequence	Description

Length: 5454 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
NO

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 2539 bp

Genome contig ID gi89161218r_5718319
PolyA signal sequence
(AATATA,-18)
+----*----+----*----+----*----+----
AGAGTTCTATGAGAAAAAATATACTTGCTATCTAT
Flanking genome sequence
(100000 - 99951)
----+----*----+----*----+----*----+----*----+----*
AAAAAAGAGAAAAAAGAAAAAAAATGAGAAAAAAGTAAGAAAAAAAAAAA

Features of the protein sequence	Description

Length: 817 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
Q8N0W4	100.0	Neuroligin-4, X...	Homo sapiens
XP_001138543	99.9	X-linked neurol...	Pan troglodytes
BAG51523	99.9	unnamed protein...	Homo sapiens
BAF83725	99.9	unnamed protein...	Homo sapiens
XP_001087740	99.4	similar to X-li...	Macaca mulatta

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB023168	0	98.8	KIAA0951
AB040913	2.4e-188	77.3	KIAA1480
AB028993	1.4e-111	74.9	KIAA1070
AB037787	2.9e-109	62.7	KIAA1366

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

FPrintScan IPR000460 437 451 PR01090 Neuroligin

IPR000460 540 561 PR01090 Neuroligin

IPR000460 570 588 PR01090 Neuroligin

IPR000460 670 699 PR01090 Neuroligin

HMMPfam IPR002018 26 591 PF00135 Carboxylesterase

ScanRegExp IPR002018 145 155 PS00941 Carboxylesterase

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR000460	437	451	PR01090	Neuroligin
IPR000460	540	561	PR01090	Neuroligin
IPR000460	570	588	PR01090	Neuroligin
IPR000460	670	699	PR01090	Neuroligin
HMMPfam	IPR002018	26	591	PF00135	Carboxylesterase
ScanRegExp	IPR002018	145	155	PS00941	Carboxylesterase

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 13 LLFTPVCVMLNSNVLLWLTALAI 35 PRIMARY 23

2 676 LSVTIAVGASLLFLNILAFAAL 697 PRIMARY 22

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	13	LLFTPVCVMLNSNVLLWLTALAI	35	PRIMARY	23
2	676	LSVTIAVGASLLFLNILAFAAL	697	PRIMARY	22

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: AGTAAATACGGCTCTGTGTTC

Primer_r
: GATAAATAAGGGACCGAGTGC

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: X

Experimental conditions

Panel name	: GeneBridge 4
Primer_f	: AGTAAATACGGCTCTGTGTTC
Primer_r	: GATAAATAAGGGACCGAGTGC
PCR product length	: 135 bp
PCR conditions	: 95 °C15 sec62 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	NO
Warning for coding interruption:	NO

Length of 3'UTR	2539 bp
Genome contig ID	gi89161218r_5718319
PolyA signal sequence (AATATA,-18)	+--------+--------+----*----+---- AGAGTTCTATGAGAAAAAATATACTTGCTATCTAT
Flanking genome sequence (100000 - 99951)	----+--------+--------+--------+--------+----* AAAAAAGAGAAAAAAGAAAAAAAATGAGAAAAAAGTAAGAAAAAAAAAAA

Gene/Protein Characteristic Table for KIAA1260

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information