HUGE

Gene/Protein Characteristic Table for KIAA1272

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK04369
Accession No. :	AB033098
Description :	250 kDa substrate of Akt.
HUGO Gene Name :	chromosome 20 open reading frame 74 (C20orf74)
Clone Name :	hk07611 [Vector Info]
Source :	Human adult brain

Features of the cloned DNA sequence	Description

Length: 3902 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Features of the protein sequence	Description

Length: 1023 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
ABC33805	100.0	akt substrate A...	Homo sapiens
CAI39939	99.9	novel protein [...	Homo sapiens
Q2PPJ7	99.9	250 kDa substra...	Homo sapiens
EAX10200	99.5	hCG22457, isofo...	Homo sapiens
XP_514544	99.5	similar to akt ...	Pan troglodytes

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB007943	1.3e-12	28.5	KIAA0474
AB011117	2.1e-10	28.8	KIAA0545
AB007900	3.9e-10	28.7	KIAA0440
AB037810	2.3e-09	29.2	KIAA1389
AB028962	4.1e-09	31.2	KIAA1039

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

HMMPfam IPR000331 852 1016 PF02145 Rap/ran-GAP

ProfileScan IPR000331 823 1023 PS50085 Rap/ran-GAP

Search method	interpro_ID	From	To	Entry	Definition
HMMPfam	IPR000331	852	1016	PF02145	Rap/ran-GAP
ProfileScan	IPR000331	823	1023	PS50085	Rap/ran-GAP

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 343 EYARCIAVCSLGVWICEELAQCT 365 SECONDARY 23

2 385 NKIVAQVACDVLQLLVSYWEKLQ 407 SECONDARY 23

3 445 VSLLLCLLDWCMALPVSVLLHPV 467 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	343	EYARCIAVCSLGVWICEELAQCT	365	SECONDARY	23
2	385	NKIVAQVACDVLQLLVSYWEKLQ	407	SECONDARY	23
3	445	VSLLLCLLDWCMALPVSVLLHPV	467	PRIMARY	23

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: GCCCTAGCATTTATTGGACCA

Primer_r
: CAGTAATGTGTTGGCAGTGCG

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 8

Experimental conditions

Panel name	: GeneBridge 4
Primer_f	: GCCCTAGCATTTATTGGACCA
Primer_r	: CAGTAATGTGTTGGCAGTGCG
PCR product length	: 148 bp
PCR conditions	: 95 °C15 sec64 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Gene/Protein Characteristic Table for KIAA1272

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information