HUGE

Gene/Protein Characteristic Table for KIAA1775

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK02053
Accession No. :	AB053448
Description :	protocadherin 21 precursor.
HUGO Gene Name :	protocadherin 21 (PCDH21)
Clone Name :	hk03826 [Vector Info]
Flexi ORF Clone :	pF1KA1775
Source :	Human adult brain

Features of the cloned DNA sequence	Description

Length: 4483 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 1904 bp

Genome contig ID gi89161187f_85844498
PolyA signal sequence
(AATAAA,-23)
+----*----+----*----+----*----+----
TTGTAAATGGAAAATAAAGTCTGTTACCCAAAGGC
Flanking genome sequence
(121765 - 121814)
----+----*----+----*----+----*----+----*----+----*
CATGCTGATCCCCTGCTCCCTGCTTTCATTTATGTTTGCTGACCTGTGGA

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 10 f 85944498 85966261 17 99.4 Perfect prediction

Features of the protein sequence	Description

Length: 858 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
Q96JP9	100.0	Protocadherin-2...	Homo sapiens
EAW80364	99.2	protocadherin 2...	Homo sapiens
XP_001154359	99.4	protocadherin 2...	Pan troglodytes
XP_001086534	95.2	similar to prot...	Macaca mulatta
Q8WN91	85.6	Protocadherin-2...	Bos taurus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB053446	4.5e-19	29.9	KIAA1773
D87469	1.4e-11	30.3	KIAA0279
AB160984	2e-09	27.2	KIAA0811
AB046841	1.2e-07	25.4	KIAA1621
AB037821	1.4e-07	24.5	KIAA1400

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

FPrintScan IPR002126 78 97 PR00205 Cadherin

IPR002126 134 163 PR00205 Cadherin

IPR002126 204 216 PR00205 Cadherin

IPR002126 224 243 PR00205 Cadherin

IPR002126 243 256 PR00205 Cadherin

IPR002126 418 444 PR00205 Cadherin

IPR002126 453 470 PR00205 Cadherin

HMMPfam IPR002126 39 112 PF00028 Cadherin

IPR002126 139 236 PF00028 Cadherin

IPR002126 250 343 PF00028 Cadherin

IPR002126 362 462 PF00028 Cadherin

IPR002126 476 566 PF00028 Cadherin

IPR002126 577 676 PF00028 Cadherin

HMMSmart IPR002126 56 132 SM00112 Cadherin

IPR002126 156 243 SM00112 Cadherin

IPR002126 267 350 SM00112 Cadherin

IPR002126 381 469 SM00112 Cadherin

IPR002126 493 573 SM00112 Cadherin

IPR002126 592 683 SM00112 Cadherin

ProfileScan IPR002126 41 134 PS50268 Cadherin

IPR002126 135 245 PS50268 Cadherin

IPR002126 246 352 PS50268 Cadherin

IPR002126 358 471 PS50268 Cadherin

IPR002126 472 575 PS50268 Cadherin

IPR002126 587 687 PS50268 Cadherin

ScanRegExp IPR002126 459 469 PS00232 Cadherin

IPR002126 563 573 PS00232 Cadherin

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR002126	78	97	PR00205	Cadherin
IPR002126	134	163	PR00205	Cadherin
IPR002126	204	216	PR00205	Cadherin
IPR002126	224	243	PR00205	Cadherin
IPR002126	243	256	PR00205	Cadherin
IPR002126	418	444	PR00205	Cadherin
IPR002126	453	470	PR00205	Cadherin
HMMPfam	IPR002126	39	112	PF00028	Cadherin
IPR002126	139	236	PF00028	Cadherin
IPR002126	250	343	PF00028	Cadherin
IPR002126	362	462	PF00028	Cadherin
IPR002126	476	566	PF00028	Cadherin
IPR002126	577	676	PF00028	Cadherin
HMMSmart	IPR002126	56	132	SM00112	Cadherin
IPR002126	156	243	SM00112	Cadherin
IPR002126	267	350	SM00112	Cadherin
IPR002126	381	469	SM00112	Cadherin
IPR002126	493	573	SM00112	Cadherin
IPR002126	592	683	SM00112	Cadherin
ProfileScan	IPR002126	41	134	PS50268	Cadherin
IPR002126	135	245	PS50268	Cadherin
IPR002126	246	352	PS50268	Cadherin
IPR002126	358	471	PS50268	Cadherin
IPR002126	472	575	PS50268	Cadherin
IPR002126	587	687	PS50268	Cadherin
ScanRegExp	IPR002126	459	469	PS00232	Cadherin
IPR002126	563	573	PS00232	Cadherin

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 4 RWAALALGLLRLCLAQANFAPHF 26 SECONDARY 23

2 700 AVGVLAGTMATVVAITVLISTAT 722 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	4	RWAALALGLLRLCLAQANFAPHF	26	SECONDARY	23
2	700	AVGVLAGTMATVVAITVLISTAT	722	PRIMARY	23

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: TACAGTCCCCAACGTGAACAG

Primer_r
: AAGCATGATCCAGCACAGTCC

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 10

Experimental conditions

Panel name	: GeneBridge 4
Primer_f	: TACAGTCCCCAACGTGAACAG
Primer_r	: AAGCATGATCCAGCACAGTCC
PCR product length	: 122 bp
PCR conditions	: 95 °C15 sec66 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Length of 3'UTR	1904 bp
Genome contig ID	gi89161187f_85844498
PolyA signal sequence (AATAAA,-23)	+--------+--------+----*----+---- TTGTAAATGGAAAATAAAGTCTGTTACCCAAAGGC
Flanking genome sequence (121765 - 121814)	----+--------+--------+--------+--------+----* CATGCTGATCCCCTGCTCCCTGCTTTCATTTATGTTTGCTGACCTGTGGA

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	10	f	85944498	85966261	17	99.4	Perfect prediction

Gene/Protein Characteristic Table for KIAA1775

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information