HUGE

Gene/Protein Characteristic Table for KIAA0405

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Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK00067
Accession No. :	AB007865
Description :	Leucine-rich repeat transmembrane protein FLRT2 precursor.
HUGO Gene Name :
Clone Name :	hg01274 [Vector Info]
Flexi ORF Clone :	pF1KA0405
Source :	Human adult brain

Features of the cloned DNA sequence	Description

Length: 7527 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
NO

Warning for coding interruption:
NO

Features of the protein sequence	Description

Length: 706 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
XP_547942	94.5	similar to Leuc...	Canis lupus fam...
O43155	100.0	Leucine-rich re...	Homo sapiens
AAI43937	99.8	FLRT2 protein [...	Homo sapiens
XP_001106330	99.5	fibronectin leu...	Macaca mulatta
BAG51774	99.5	unnamed protein...	Homo sapiens

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB040902	3.8e-57	47.1	KIAA1469
AB046800	1.5e-10	30.0	KIAA1580
AB040930	1.1e-08	24.0	KIAA1497
AB040898	1.4e-07	26.2	KIAA1465
AB020655	8.2e-07	28.2	KIAA0848

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

FPrintScan IPR001611 207 220 PR00019 Leucine-rich repeat

IPR001611 321 334 PR00019 Leucine-rich repeat

HMMPfam IPR000372 81 108 PF01462 Leucine-rich repeat

IPR001611 110 133 PF00560 Leucine-rich repeat

IPR001611 156 178 PF00560 Leucine-rich repeat

IPR001611 180 204 PF00560 Leucine-rich repeat

IPR001611 206 224 PF00560 Leucine-rich repeat

IPR001611 227 249 PF00560 Leucine-rich repeat

IPR001611 251 275 PF00560 Leucine-rich repeat

IPR001611 277 298 PF00560 Leucine-rich repeat

IPR001611 299 321 PF00560 Leucine-rich repeat

IPR001611 323 345 PF00560 Leucine-rich repeat

IPR000483 382 407 PF01463 Cysteine-rich flanking region

IPR003961 466 548 PF00041 Fibronectin

HMMSmart IPR000372 81 113 SM00013 Leucine-rich repeat

IPR003591 153 177 SM00369 Leucine-rich repeat

IPR003591 178 203 SM00369 Leucine-rich repeat

IPR003591 205 227 SM00369 Leucine-rich repeat

IPR003591 228 248 SM00369 Leucine-rich repeat

IPR003591 249 274 SM00369 Leucine-rich repeat

IPR003591 298 320 SM00369 Leucine-rich repeat

IPR003591 321 344 SM00369 Leucine-rich repeat

IPR000483 356 407 SM00082 Cysteine-rich flanking region

ProfileScan IPR003961 466 556 PS50853 Fibronectin

ScanRegExp IPR013090 85 95 PS00119 Phospholipase A2

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR001611	207	220	PR00019	Leucine-rich repeat
IPR001611	321	334	PR00019	Leucine-rich repeat
HMMPfam	IPR000372	81	108	PF01462	Leucine-rich repeat
IPR001611	110	133	PF00560	Leucine-rich repeat
IPR001611	156	178	PF00560	Leucine-rich repeat
IPR001611	180	204	PF00560	Leucine-rich repeat
IPR001611	206	224	PF00560	Leucine-rich repeat
IPR001611	227	249	PF00560	Leucine-rich repeat
IPR001611	251	275	PF00560	Leucine-rich repeat
IPR001611	277	298	PF00560	Leucine-rich repeat
IPR001611	299	321	PF00560	Leucine-rich repeat
IPR001611	323	345	PF00560	Leucine-rich repeat
IPR000483	382	407	PF01463	Cysteine-rich flanking region
IPR003961	466	548	PF00041	Fibronectin
HMMSmart	IPR000372	81	113	SM00013	Leucine-rich repeat
IPR003591	153	177	SM00369	Leucine-rich repeat
IPR003591	178	203	SM00369	Leucine-rich repeat
IPR003591	205	227	SM00369	Leucine-rich repeat
IPR003591	228	248	SM00369	Leucine-rich repeat
IPR003591	249	274	SM00369	Leucine-rich repeat
IPR003591	298	320	SM00369	Leucine-rich repeat
IPR003591	321	344	SM00369	Leucine-rich repeat
IPR000483	356	407	SM00082	Cysteine-rich flanking region
ProfileScan	IPR003961	466	556	PS50853	Fibronectin
ScanRegExp	IPR013090	85	95	PS00119	Phospholipase A2

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 20 SHFDFAVYFFFSFSFSHHIVFYF 42 SECONDARY 23

2 479 NDTSIQVSWLSLFTVMAYKLTWV 501 SECONDARY 23

3 586 PFLLAGLIGGAVIFVLVVLLSVF 608 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	20	SHFDFAVYFFFSFSFSHHIVFYF	42	SECONDARY	23
2	479	NDTSIQVSWLSLFTVMAYKLTWV	501	SECONDARY	23
3	586	PFLLAGLIGGAVIFVLVVLLSVF	608	PRIMARY	23

Expression profile	Description

: RT-PCR Description

Experimental conditions

Primer_f
: AATCTTTCAGCCCCTTATCAG

Primer_r
: AGGGGCATTTGTAAAGGTGTC

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR	Description

RH mapping information	Description

Chromosome No.

: 14

Experimental conditions

Panel name	: GeneBridge 4
Primer_f	: AATCTTTCAGCCCCTTATCAG
Primer_r	: AGGGGCATTTGTAAAGGTGTC
PCR product length	: 204 bp
PCR conditions	: 95 °C15 sec62 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	NO
Warning for coding interruption:	NO

Gene/Protein Characteristic Table for KIAA0405

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information