Gene/Protein Characteristic Table for KIAA0644
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Product ID ORK00587
Accession No AB014544
Description TLR4 interactor with leucine-rich repeats
Clone name hj03618
Vector information
The cDNA fragment was inserted at the SalI-NotI site of the ...
cDNA sequence DNA sequence (4933 bp)
Predicted protein sequence (887 aa)
Flexi ORF Clone FXC00587
Source Human adult brain
Rouge ID mKIAA0644 by Kazusa Mouse cDNA Project
Features of the cloned cDNA sequence
Description

Length: 4933 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis).

N-terminal truncation Coding interruption
cloned DNA seq No warning No warning
Features of the protein sequence
Description

Length: 887 aa
Result of homology search against nr database (FASTA output, Multiple alignment)
Entry Exp ID% Protein Source
NP_055632 0 99.9 hypothetical pr...
Homo sapiens
XP_001088293 0 96.2 similar to CG75...
Macaca mulatta
BAC34634 0 88.6 unnamed protein...
Mus musculus
XP_001381576 1.2e-212 76.8 hypothetical pr...
Monodelphis dom...
XP_539495 1.1e-181 88.1 similar to Carb...
Canis lupus fam...
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of homology search against HUGE database (FASTA output, Multiple alignment)
Entry Exp ID% HUGE_ID
AB007876 5.8e-11 28.6 KIAA0416
AB018349 1e-07 27.0 KIAA0806
AB011537 1.4e-06 26.1 KIAA0813
AB033072 3.1e-06 32.6 KIAA1246
AB011538 4e-06 27.3 KIAA0814
The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.
Result of motif / domain search (InterProScan and SOSUI)

Result of InterProScan

Search method interpro_ID From To Entry Definition
FPrintScan IPR001611 161 174 PR00019 Leucine-rich repeat
IPR001611 376 389 PR00019 Leucine-rich repeat
HMMPfam IPR001611 160 182 PF00560 Leucine-rich repeat
IPR001611 184 206 PF00560 Leucine-rich repeat
IPR001611 208 230 PF00560 Leucine-rich repeat
IPR001611 232 254 PF00560 Leucine-rich repeat
IPR001611 256 278 PF00560 Leucine-rich repeat
IPR001611 306 328 PF00560 Leucine-rich repeat
IPR001611 330 352 PF00560 Leucine-rich repeat
IPR001611 354 376 PF00560 Leucine-rich repeat
IPR001611 378 400 PF00560 Leucine-rich repeat
IPR001611 402 424 PF00560 Leucine-rich repeat
IPR000483 463 491 PF01463 Cysteine-rich flanking region
HMMSmart IPR003591 158 181 SM00369 Leucine-rich repeat
IPR003591 182 205 SM00369 Leucine-rich repeat
IPR003591 206 229 SM00369 Leucine-rich repeat
IPR003591 230 253 SM00369 Leucine-rich repeat
IPR003591 254 277 SM00369 Leucine-rich repeat
IPR003591 278 303 SM00369 Leucine-rich repeat
IPR003591 304 327 SM00369 Leucine-rich repeat
IPR003591 328 351 SM00369 Leucine-rich repeat
IPR003591 352 375 SM00369 Leucine-rich repeat
IPR003591 376 399 SM00369 Leucine-rich repeat
IPR003591 400 423 SM00369 Leucine-rich repeat
IPR000483 435 491 SM00082 Cysteine-rich flanking region

Prediction of transmembrane (TM) segments
Method No. N terminal transmembrane region C terminal type length
SOSUI2 1 772 QLLTLALLTVNALLVLLALAAWA 794 PRIMARY 23
Expression profile
Description

RT-PCR
RT-PCR-ELISA
Experimental conditions
Primer_f CCAGCAGGGTAATATTGAGTC
Primer_r AAGTAGAACACAGATCCAGGC
PCR conditions 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RH mapping information
Description

Chromosome No. 7
Experimental conditions
Panel name GeneBridge 4
Primer_f CCAGCAGGGTAATATTGAGTC
Primer_r AAGTAGAACACAGATCCAGGC
PCR product length 123 bp
PCR conditions 95 °C15 sec62 °C60 sec30 cycles
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