HUGE

Gene/Protein Characteristic Table for KIAA0379

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK00521
Accession No. :	AB002377
Description :	Ankyrin repeat domain-containing protein 28.
HUGO Gene Name :	ankyrin repeat domain 28 (ANKRD28)
Clone Name :	hh00505s1 [Vector Info]
Flexi ORF Clone :	pF1KSDA0379
Source :	Human adult brain
Note :	We replaced hh00505, former representative clones for KIAA0379 with hh00505s1. (2002/5/10)

Features of the cloned DNA sequence	Description

Length: 4408 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 1227 bp

Genome contig ID gi89161205r_15583750
PolyA signal sequence
(AATAAA,-21)
+----*----+----*----+----*----+----
GACCTTTTAAAAGAAATAAAGTTTTTTAATGCAAT
Flanking genome sequence
(100000 - 99951)
----+----*----+----*----+----*----+----*----+----*
AAATCAAGTGTCTGTCTCTTTTACATGCAAACTTCTTTTCCCTTAAACTG

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 3 r 15683750 15875933 29 99.8 Perfect prediction

Features of the protein sequence	Description

Length: 1059 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
EAW64259	100.0	ankyrin repeat ...	Homo sapiens
XP_534254	99.0	similar to anky...	Canis lupus fam...
XP_516310	99.8	ankyrin repeat ...	Pan troglodytes
O15084	100.0	Serine/threonin...	Homo sapiens
EDL24818	98.2	ankyrin repeat ...	Mus musculus

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB033049	3.7e-32	32.8	KIAA1223
AB033076	4e-26	28.6	KIAA1250
AB014597	8.1e-25	26.7	KIAA0697
D86982	1.5e-18	37.4	KIAA0229
AB037755	6.2e-18	31.3	KIAA1334

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

[ zoom out (x2) ]

Result of InterProScan

Search method interpro_ID From To Entry Definition

FPrintScan IPR002110 345 357 PR01415 Ankyrin

IPR002110 704 716 PR01415 Ankyrin

HMMPfam IPR002110 21 45 PF00023 Ankyrin

IPR002110 46 78 PF00023 Ankyrin

IPR002110 79 111 PF00023 Ankyrin

IPR002110 112 144 PF00023 Ankyrin

IPR002110 145 177 PF00023 Ankyrin

IPR002110 178 210 PF00023 Ankyrin

IPR002110 211 243 PF00023 Ankyrin

IPR002110 244 276 PF00023 Ankyrin

IPR002110 277 310 PF00023 Ankyrin

IPR002110 311 343 PF00023 Ankyrin

IPR002110 344 376 PF00023 Ankyrin

IPR002110 377 409 PF00023 Ankyrin

IPR002110 410 442 PF00023 Ankyrin

IPR002110 443 475 PF00023 Ankyrin

IPR002110 476 509 PF00023 Ankyrin

IPR002110 510 543 PF00023 Ankyrin

IPR002110 558 587 PF00023 Ankyrin

IPR002110 588 620 PF00023 Ankyrin

IPR002110 622 654 PF00023 Ankyrin

IPR002110 658 690 PF00023 Ankyrin

IPR002110 691 723 PF00023 Ankyrin

IPR002110 724 753 PF00023 Ankyrin

IPR002110 761 784 PF00023 Ankyrin

IPR002110 793 826 PF00023 Ankyrin

IPR002110 828 860 PF00023 Ankyrin

IPR002110 861 894 PF00023 Ankyrin

IPR002110 895 927 PF00023 Ankyrin

IPR002110 931 963 PF00023 Ankyrin

HMMSmart IPR002110 13 42 SM00248 Ankyrin

IPR002110 46 75 SM00248 Ankyrin

IPR002110 79 108 SM00248 Ankyrin

IPR002110 112 141 SM00248 Ankyrin

IPR002110 145 174 SM00248 Ankyrin

IPR002110 178 207 SM00248 Ankyrin

IPR002110 211 240 SM00248 Ankyrin

IPR002110 244 273 SM00248 Ankyrin

IPR002110 277 307 SM00248 Ankyrin

IPR002110 311 340 SM00248 Ankyrin

IPR002110 344 373 SM00248 Ankyrin

IPR002110 377 406 SM00248 Ankyrin

IPR002110 410 439 SM00248 Ankyrin

IPR002110 443 472 SM00248 Ankyrin

IPR002110 476 506 SM00248 Ankyrin

IPR002110 510 540 SM00248 Ankyrin

IPR002110 555 584 SM00248 Ankyrin

IPR002110 588 617 SM00248 Ankyrin

IPR002110 622 651 SM00248 Ankyrin

IPR002110 658 687 SM00248 Ankyrin

IPR002110 691 720 SM00248 Ankyrin

IPR002110 724 753 SM00248 Ankyrin

IPR002110 761 791 SM00248 Ankyrin

IPR002110 793 824 SM00248 Ankyrin

IPR002110 828 857 SM00248 Ankyrin

IPR002110 861 891 SM00248 Ankyrin

IPR002110 895 924 SM00248 Ankyrin

IPR002110 931 960 SM00248 Ankyrin

ProfileScan IPR002110 13 997 PS50297 Ankyrin

IPR002110 46 78 PS50088 Ankyrin

IPR002110 79 111 PS50088 Ankyrin

IPR002110 112 144 PS50088 Ankyrin

IPR002110 145 177 PS50088 Ankyrin

IPR002110 178 210 PS50088 Ankyrin

IPR002110 211 243 PS50088 Ankyrin

IPR002110 244 276 PS50088 Ankyrin

IPR002110 277 310 PS50088 Ankyrin

IPR002110 311 343 PS50088 Ankyrin

IPR002110 344 376 PS50088 Ankyrin

IPR002110 377 409 PS50088 Ankyrin

IPR002110 410 442 PS50088 Ankyrin

IPR002110 443 475 PS50088 Ankyrin

IPR002110 476 509 PS50088 Ankyrin

IPR002110 555 587 PS50088 Ankyrin

IPR002110 588 620 PS50088 Ankyrin

IPR002110 622 654 PS50088 Ankyrin

IPR002110 658 690 PS50088 Ankyrin

IPR002110 691 723 PS50088 Ankyrin

IPR002110 724 756 PS50088 Ankyrin

IPR002110 761 783 PS50088 Ankyrin

IPR002110 828 860 PS50088 Ankyrin

IPR002110 861 894 PS50088 Ankyrin

IPR002110 931 963 PS50088 Ankyrin

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR002110	345	357	PR01415	Ankyrin
IPR002110	704	716	PR01415	Ankyrin
HMMPfam	IPR002110	21	45	PF00023	Ankyrin
IPR002110	46	78	PF00023	Ankyrin
IPR002110	79	111	PF00023	Ankyrin
IPR002110	112	144	PF00023	Ankyrin
IPR002110	145	177	PF00023	Ankyrin
IPR002110	178	210	PF00023	Ankyrin
IPR002110	211	243	PF00023	Ankyrin
IPR002110	244	276	PF00023	Ankyrin
IPR002110	277	310	PF00023	Ankyrin
IPR002110	311	343	PF00023	Ankyrin
IPR002110	344	376	PF00023	Ankyrin
IPR002110	377	409	PF00023	Ankyrin
IPR002110	410	442	PF00023	Ankyrin
IPR002110	443	475	PF00023	Ankyrin
IPR002110	476	509	PF00023	Ankyrin
IPR002110	510	543	PF00023	Ankyrin
IPR002110	558	587	PF00023	Ankyrin
IPR002110	588	620	PF00023	Ankyrin
IPR002110	622	654	PF00023	Ankyrin
IPR002110	658	690	PF00023	Ankyrin
IPR002110	691	723	PF00023	Ankyrin
IPR002110	724	753	PF00023	Ankyrin
IPR002110	761	784	PF00023	Ankyrin
IPR002110	793	826	PF00023	Ankyrin
IPR002110	828	860	PF00023	Ankyrin
IPR002110	861	894	PF00023	Ankyrin
IPR002110	895	927	PF00023	Ankyrin
IPR002110	931	963	PF00023	Ankyrin
HMMSmart	IPR002110	13	42	SM00248	Ankyrin
IPR002110	46	75	SM00248	Ankyrin
IPR002110	79	108	SM00248	Ankyrin
IPR002110	112	141	SM00248	Ankyrin
IPR002110	145	174	SM00248	Ankyrin
IPR002110	178	207	SM00248	Ankyrin
IPR002110	211	240	SM00248	Ankyrin
IPR002110	244	273	SM00248	Ankyrin
IPR002110	277	307	SM00248	Ankyrin
IPR002110	311	340	SM00248	Ankyrin
IPR002110	344	373	SM00248	Ankyrin
IPR002110	377	406	SM00248	Ankyrin
IPR002110	410	439	SM00248	Ankyrin
IPR002110	443	472	SM00248	Ankyrin
IPR002110	476	506	SM00248	Ankyrin
IPR002110	510	540	SM00248	Ankyrin
IPR002110	555	584	SM00248	Ankyrin
IPR002110	588	617	SM00248	Ankyrin
IPR002110	622	651	SM00248	Ankyrin
IPR002110	658	687	SM00248	Ankyrin
IPR002110	691	720	SM00248	Ankyrin
IPR002110	724	753	SM00248	Ankyrin
IPR002110	761	791	SM00248	Ankyrin
IPR002110	793	824	SM00248	Ankyrin
IPR002110	828	857	SM00248	Ankyrin
IPR002110	861	891	SM00248	Ankyrin
IPR002110	895	924	SM00248	Ankyrin
IPR002110	931	960	SM00248	Ankyrin
ProfileScan	IPR002110	13	997	PS50297	Ankyrin
IPR002110	46	78	PS50088	Ankyrin
IPR002110	79	111	PS50088	Ankyrin
IPR002110	112	144	PS50088	Ankyrin
IPR002110	145	177	PS50088	Ankyrin
IPR002110	178	210	PS50088	Ankyrin
IPR002110	211	243	PS50088	Ankyrin
IPR002110	244	276	PS50088	Ankyrin
IPR002110	277	310	PS50088	Ankyrin
IPR002110	311	343	PS50088	Ankyrin
IPR002110	344	376	PS50088	Ankyrin
IPR002110	377	409	PS50088	Ankyrin
IPR002110	410	442	PS50088	Ankyrin
IPR002110	443	475	PS50088	Ankyrin
IPR002110	476	509	PS50088	Ankyrin
IPR002110	555	587	PS50088	Ankyrin
IPR002110	588	620	PS50088	Ankyrin
IPR002110	622	654	PS50088	Ankyrin
IPR002110	658	690	PS50088	Ankyrin
IPR002110	691	723	PS50088	Ankyrin
IPR002110	724	756	PS50088	Ankyrin
IPR002110	761	783	PS50088	Ankyrin
IPR002110	828	860	PS50088	Ankyrin
IPR002110	861	894	PS50088	Ankyrin
IPR002110	931	963	PS50088	Ankyrin

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

- - - - - - -

Method	No.	N terminal	transmembrane region	C terminal	type	length
-	-	-	-	-	-	-

Expression profile	Description

: RT-PCR Description

Experimental conditions

Primer_f
: CCCCAAAATTTACAGCTACAC

Primer_r
: GCTCTAGAACTACTTTGGGTG

PCR conditions
: 95 °C30 sec61 °C30 sec72 °C60 sec30 cycles

RT-PCR	Description

RH mapping information	Description

Chromosome No.

: 3

Experimental conditions

Panel name	: GeneBridge 4
Primer_f	: CCCCAAAATTTACAGCTACAC
Primer_r	: GCTCTAGAACTACTTTGGGTG
PCR product length	: 121 bp
PCR conditions	: 95 °C15 sec62 °C60 sec30 cycles

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Length of 3'UTR	1227 bp
Genome contig ID	gi89161205r_15583750
PolyA signal sequence (AATAAA,-21)	+--------+--------+----*----+---- GACCTTTTAAAAGAAATAAAGTTTTTTAATGCAAT
Flanking genome sequence (100000 - 99951)	----+--------+--------+--------+--------+----* AAATCAAGTGTCTGTCTCTTTTACATGCAAACTTCTTTTCCCTTAAACTG

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	3	r	15683750	15875933	29	99.8	Perfect prediction

Gene/Protein Characteristic Table for KIAA0379

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information