HUGE

Gene/Protein Characteristic Table for KIAA1021

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK04210
Accession No. :	AB028944
Description :	Probable phospholipid-transporting ATPase IH.
HUGO Gene Name :	ATPase, class VI, type 11A (ATP11A)
Clone Name :	af10412 [Vector Info]
Source :	Human brain (amygdala)
Note :	We replaced fg00592, former representative clones for KIAA1021 with af10412. (2005/08/06)

Features of the cloned DNA sequence	Description

Length: 7611 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
YES

Integrity of 3' end

Length of 3'UTR 4301 bp

Genome contig ID gi51511729f_112387506
PolyA signal sequence
(None)
+----*----+----*----+----*----+----
GCCAGCCTTCCGCCACGAGCCAGCTGGGAAGGGCC
Flanking genome sequence
(200916 - 200965)
----+----*----+----*----+----*----+----*----+----*
GCGGCCGCCTAAAGCCCCAGTCAACCCAGCCTGTGTCTGAGCAGACAGGG

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 13 f 112487506 112588420 29 99.4 Perfect prediction

Features of the protein sequence	Description

Length: 1102 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
P98196	99.9	Probable phosph...	Homo sapiens
ABY40831	99.3	ATPase, Class V...	Papio anubis
NP_115565	99.9	ATPase, class V...	Homo sapiens
XP_509744	99.7	ATPase, Class V...	Pan troglodytes
XP_001101635	99.3	similar to ATPa...	Macaca mulatta

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB023173	1.7e-93	57.9	KIAA0956
AB075819	8.6e-79	34.8	KIAA1939
AB032963	5.4e-74	36.2	KIAA1137
AB040920	1.1e-60	38.0	KIAA1487
AB018258	1.6e-58	32.1	KIAA0715

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

FPrintScan IPR001757 380 394 PR00119 ATPase

IPR001757 791 810 PR00119 ATPase

HMMPfam IPR005834 376 814 PF00702 Haloacid dehalogenase-like hydrolase

HMMTigr IPR006539 13 1078 TIGR01652 Phospholipid-translocating P-type ATPase

IPR001757 62 161 TIGR01494 ATPase

IPR001757 622 672 TIGR01494 ATPase

IPR001757 763 871 TIGR01494 ATPase

ScanRegExp IPR001757 382 388 PS00154 ATPase

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR001757	380	394	PR00119	ATPase
IPR001757	791	810	PR00119	ATPase
HMMPfam	IPR005834	376	814	PF00702	Haloacid dehalogenase-like hydrolase
HMMTigr	IPR006539	13	1078	TIGR01652	Phospholipid-translocating P-type ATPase
IPR001757	62	161	TIGR01494	ATPase
IPR001757	622	672	TIGR01494	ATPase
IPR001757	763	871	TIGR01494	ATPase
ScanRegExp	IPR001757	382	388	PS00154	ATPase

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 49 FLVQLIIDTPTSPVTSGLPLFFV 71 PRIMARY 23

2 261 MNAFLIVYLCILISKALINTVLK 283 PRIMARY 23

3 315 TDFLAFMVLFNYIIPVSMYVTVE 337 PRIMARY 23

4 852 QYFFYKNVCFIFPQFLYQFFCGF 874 SECONDARY 23

5 884 YLTLYNISFTSLPILLYSLMEQH 906 SECONDARY 23

6 934 IYWTLLGLFDALVFFFGAYFVFE 956 SECONDARY 23

7 971 TFGTLVFTVMVFTVTLKLALDT 992 PRIMARY 22

8 1000 HFVIWGSLLFYVVFSLLWGGVIW 1022 PRIMARY 23

9 1034 FIQMLSSGPAWLAIVLLVTISLL 1056 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	49	FLVQLIIDTPTSPVTSGLPLFFV	71	PRIMARY	23
2	261	MNAFLIVYLCILISKALINTVLK	283	PRIMARY	23
3	315	TDFLAFMVLFNYIIPVSMYVTVE	337	PRIMARY	23
4	852	QYFFYKNVCFIFPQFLYQFFCGF	874	SECONDARY	23
5	884	YLTLYNISFTSLPILLYSLMEQH	906	SECONDARY	23
6	934	IYWTLLGLFDALVFFFGAYFVFE	956	SECONDARY	23
7	971	TFGTLVFTVMVFTVTLKLALDT	992	PRIMARY	22
8	1000	HFVIWGSLLFYVVFSLLWGGVIW	1022	PRIMARY	23
9	1034	FIQMLSSGPAWLAIVLLVTISLL	1056	PRIMARY	23

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: GCATTGGACACACACTACTGG

Primer_r
: AACACGTAGTACATCCTCTGG

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 13

Experimental conditions

Panel name	: UniGene
Primer_f	: -
Primer_r	: -
PCR product length	: -
PCR conditions	: -

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	YES

Length of 3'UTR	4301 bp
Genome contig ID	gi51511729f_112387506
PolyA signal sequence (None)	+--------+--------+----*----+---- GCCAGCCTTCCGCCACGAGCCAGCTGGGAAGGGCC
Flanking genome sequence (200916 - 200965)	----+--------+--------+--------+--------+----* GCGGCCGCCTAAAGCCCCAGTCAACCCAGCCTGTGTCTGAGCAGACAGGG

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	13	f	112487506	112588420	29	99.4	Perfect prediction

Primer_f	: GCATTGGACACACACTACTGG
Primer_r	: AACACGTAGTACATCCTCTGG
PCR conditions	: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

Gene/Protein Characteristic Table for KIAA1021

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information