HUGE

Gene/Protein Characteristic Table for KIAA1137

Link to : Rouge \| GTOP \| SWISS-PROT/TrEMBL \| GeneCards\| RefDIC
Features : DNA sequence \| Protein sequence \| Expression \| Mapping

Product ID :	ORK04226
Accession No. :	AB032963
Description :	Probable phospholipid-transporting ATPase ID.
HUGO Gene Name :	ATPase, class I, type 8B, member 2 (ATP8B2)
Clone Name :	hj03907 [Vector Info]
Source :	Human adult brain

Features of the cloned DNA sequence	Description

Length: 4990 bp
Physical map
Restriction map
Prediction of protein coding region (GeneMark analysis) for :
cloned DNA seq.
Warning for N-terminal truncation:
YES

Warning for coding interruption:
NO

Integrity of 3' end

Length of 3'UTR 2186 bp

Genome contig ID gi89161185f_152473624
PolyA signal sequence
(TATAAA,-21)
+----*----+----*----+----*----+----
GAAAAATGCCTTTTTATAAAATTTCAATTTCTGAG
Flanking genome sequence
(116783 - 116832)
----+----*----+----*----+----*----+----*----+----*
AAGTGTGTAATTTGTCTCTTTTCTGATGTTTAACCAAGACTGGTGGTGAA

Ensembl ContigView (Add our DAS server as a DAS source)

Chr f/r start end exon identity class

ContigView(URL based/DAS) 1 f 152573624 152590405 18 99.4 Perfect prediction

Features of the protein sequence	Description

Length: 933 aa

Result of homology search against nr database (FASTA output, Multiple alignment)

Entry	ID%	Protein	Source
EAW53208	99.9	ATPase, Class I...	Homo sapiens
P98198	99.9	Probable phosph...	Homo sapiens
XP_524888	99.9	ATPase, Class I...	Pan troglodytes
AAQ19027	99.9	possible aminop...	Homo sapiens
XP_001114383	99.5	ATPase, Class I...	Macaca mulatta

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of homology search against other HUGE database (FASTA output, Multiple alignment)

Entry	Exp	ID%	HUGE_ID
AB075819	0	67.9	KIAA1939
AB028944	1.4e-81	36.3	KIAA1021
AB040920	1e-72	35.7	KIAA1487
AB011138	5.7e-70	32.6	KIAA0566
AB018258	1.8e-69	32.0	KIAA0715

The numbers on the left and right sides of a black line in the graphical overview indicate the lengths (in amino acid residues) of the non-homologous N-terminal and C-terminal portions flanking the homologous region (indicated by the black line), respectively.

Result of motif / domain search (InterProScan and SOSUI)

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Result of InterProScan

Search method interpro_ID From To Entry Definition

FPrintScan IPR001757 133 147 PR00119 ATPase

IPR001757 555 574 PR00119 ATPase

HMMTigr IPR006539 1 844 TIGR01652 Phospholipid-translocating P-type ATPase

IPR001757 63 154 TIGR01494 ATPase

IPR001757 385 434 TIGR01494 ATPase

IPR001757 520 635 TIGR01494 ATPase

ScanRegExp IPR001757 135 141 PS00154 ATPase

Search method	interpro_ID	From	To	Entry	Definition
FPrintScan	IPR001757	133	147	PR00119	ATPase
IPR001757	555	574	PR00119	ATPase
HMMTigr	IPR006539	1	844	TIGR01652	Phospholipid-translocating P-type ATPase
IPR001757	63	154	TIGR01494	ATPase
IPR001757	385	434	TIGR01494	ATPase
IPR001757	520	635	TIGR01494	ATPase
ScanRegExp	IPR001757	135	141	PS00154	ATPase

Prediction of transmembrane (TM) segments

Method No. N terminal transmembrane region C terminal type length

SOSUI2 1 16 MNTLVLWIFGFLVCMGVILAIGN 38 PRIMARY 23

2 65 SGFLSFWSYIIILNTVVPISLYV 87 PRIMARY 23

3 617 YFFYKNFAFTMVHFWFGFFCGFS 639 SECONDARY 23

4 649 ITLYNIVYTSLPVLAMGVFDQDV 671 SECONDARY 23

5 698 FICIAQGIYTSVLMFFIPYGVFA 720 SECONDARY 23

6 733 YQSFAVTVATSLVIVVSVQIGLD 755 PRIMARY 23

7 761 AINHFFIWGSLAVYFAILFAMHS 783 SECONDARY 23

8 808 TVWLTIVLTTVVCIMPVVAFRFL 830 PRIMARY 23

Method	No.	N terminal	transmembrane region	C terminal	type	length
SOSUI2	1	16	MNTLVLWIFGFLVCMGVILAIGN	38	PRIMARY	23
2	65	SGFLSFWSYIIILNTVVPISLYV	87	PRIMARY	23
3	617	YFFYKNFAFTMVHFWFGFFCGFS	639	SECONDARY	23
4	649	ITLYNIVYTSLPVLAMGVFDQDV	671	SECONDARY	23
5	698	FICIAQGIYTSVLMFFIPYGVFA	720	SECONDARY	23
6	733	YQSFAVTVATSLVIVVSVQIGLD	755	PRIMARY	23
7	761	AINHFFIWGSLAVYFAILFAMHS	783	SECONDARY	23
8	808	TVWLTIVLTTVVCIMPVVAFRFL	830	PRIMARY	23

Expression profile	Description

: RT-PCR-ELISA Description
: Experimental conditions

Primer_f
: AGCATCTATGAGGAGGTTGAG

Primer_r
: AAACCTCAGTCATGTCATCCG

PCR conditions
: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

RT-PCR-ELISA	Description

RH mapping information	Description

Chromosome No.

: 1

Experimental conditions

Panel name	: unigene
Primer_f	: -
Primer_r	: -
PCR product length	: -
PCR conditions	: -

How to obtain KIAA clone(s) Back to the HUGE Protein Database homepage

	cloned DNA seq.
Warning for N-terminal truncation:	YES
Warning for coding interruption:	NO

Length of 3'UTR	2186 bp
Genome contig ID	gi89161185f_152473624
PolyA signal sequence (TATAAA,-21)	+--------+--------+----*----+---- GAAAAATGCCTTTTTATAAAATTTCAATTTCTGAG
Flanking genome sequence (116783 - 116832)	----+--------+--------+--------+--------+----* AAGTGTGTAATTTGTCTCTTTTCTGATGTTTAACCAAGACTGGTGGTGAA

	Chr	f/r	start	end	exon	identity	class
ContigView(URL based/DAS)	1	f	152573624	152590405	18	99.4	Perfect prediction

Primer_f	: AGCATCTATGAGGAGGTTGAG
Primer_r	: AAACCTCAGTCATGTCATCCG
PCR conditions	: 95 °C30 sec55 °C30 sec72 °C60 sec30 cycles

Gene/Protein Characteristic Table for KIAA1137

Features of the cloned DNA sequence

Features of the protein sequence

Expression profile

RH mapping information